Sudha Raj

How prevalent is vitamin B12 deficiency among vegetarians

Vegetarians are at risk for vitamin B(12) (B12) deficiency due to suboptimal intake. The goal of the present literature review was to assess the rate of B12 depletion and deficiency among vegetarians and vegans. Using a PubMed search to identify relevant publications, 18 articles were found that reported B12 deficiency rates from studies that identified deficiency by measuring methylmalonic acid, holo-transcobalamin II, or both. The deficiency rates reported for specific populations were as follows: 62% among pregnant women, between 25% and almost 86% among children, 21-41% among adolescents, and 11-90% among the elderly. Higher rates of deficiency were reported among vegans compared with vegetarians and among individuals who had adhered to a vegetarian diet since birth compared with those who had adopted such a diet later in life. The main finding of this review is that vegetarians develop B12 depletion or deficiency regardless of demographic characteristics, place of residency, age, or type of vegetarian diet. Vegetarians should thus take preventive measures to ensure adequate intake of this vitamin, including regular consumption of supplements containing B12.

Understanding Vitamin B12

Vitamin B12 (B12) is essential in activating folate needed in DNA synthesis. Inadequate intake results in the impairment of nerve transmission and inadequate synthesis of erythrocytes and other hematological cells. Two separate mechanisms of B12 absorption exist, a receptor-mediated endocytosis that occurs in the distal ileum and the mass-action pharmacologic mechanism. The recommended dietary allowance for B12 for adults issued by the Institute of Medicine is 2.4 µg/d. B12 is only found in meats and other foods of animal origin. B12 deficiency is widespread. Two main causes of deficiency include inadequate absorption and intake. Elderly and vegetarians are at highest risk for deficiency. Prevalence of deficiency ranges from 7% of the US population 3 years and older to 90% among vegans. The best way to assess deficiency is by using methylmalonic acid. Populations at risk could benefit from using B12 supplements and from fortification of flour.

A Vegetarian Diet for Weight Management

I S W ith obesity impacting more than 30% of adult Americans in most age groups and with overweight affecting even more of them (1), at present he majority of Americans remain at risk for obesityelated health complications. These include heart disase, diabetes mellitus, gallbladder disease, osteoarthriis, and some forms of cancer (2). To combat the obesity pidemic and its subsequent deleterious health impact, egistered dietitians can learn various evidence-based ntervention strategies to counsel individuals in weight anagement. One such approach can include following a egetarian dietary pattern.

Effectiveness of a Group-Based Culturally Tailored Lifestyle Intervention Program on Changes in Risk Factors for Type 2 Diabetes among Asian Indians in the United States

This study used an experimental, pretest-posttest control group repeated measures design to evaluate the effectiveness of a community-based culturally appropriate lifestyle intervention program to reduce the risk for type 2 diabetes (T2DM) among Gujarati Asian Indians (AIs) in an urban community in the US. Participants included 70 adult AIs in the greater Houston metropolitan area. The primary outcomes were reduction in weight and hemoglobin A1c (HbA1c) and improvement in physical activity. Participants were screened for risk factors and randomly assigned to a 12-week group-based lifestyle intervention program (n = 34) or a control group (n = 36) that received standard print material on diabetes prevention. Participants also completed clinical measures and self-reported questionnaires about physical activity, social, and lifestyle habits at 0, 3, and 6 months. No significant baseline differences were noted between groups. While a significant decline in weight and increase in physical activity was observed in all participants, the intervention group lowered their HbA1c (p < 0.0005) and waist circumference (p = 0.04) significantly as compared to the control group. Findings demonstrated that participation in a culturally tailored, lifestyle intervention program in a community setting can effectively reduce weight, waist circumference, and HbA1c among Gujarati AIs living in the US.

Barriers to and Facilitators of Dietetics Education among Students of Diverse Backgrounds: Results of a Survey

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Nutrition screening tools and the prediction of clinical outcomes among Chinese hospitalized gastrointestinal disease patients

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Attitudes of Processors and Distributors towards Processing in the Natural Foods Industry

Nutrition risk Screening 2002 (NRS-2002) and Subjective Global Assessment (SGA) are widely used screening tools but have not been compared in a Chinese population. We conducted secondary data analysis of a cross-sectional study which included 332 hospitalized gastrointestinal disease patients, collected by the Gastrointestinal department of Peking Union Medical College Hospital (PUMCH) in 2008. Results of NRS-2002 and SGA screening tools, complications, length of stay (LOS), cost, and death were measured. The agreement between the tools was assessed via Kappa (κ) statistics. The performance of NRS-2002 and SGA in predicting LOS and cost was assessed via linear regression. The complications and death prediction of tools was assessed using receiver operating characteristic (ROC) curves. NRS-2002 and SGA identified nutrition risk at 59.0% and 45.2% respectively. Moderate agreement (κ >0.50) between the two tools was found among all age groups except individuals aged ≤ 20, which only slight agreement was found (κ = 0.087). NRS-2002 (R square 0.130) and SGA (R square 0.140) did not perform differently in LOS prediction. The cost prediction of NRS-2002 (R square 0.198) and SGA (R square 0.190) were not significantly different. There was no difference between NRS-2002 (infectious complications: area under ROC (AUROC) = 0.615, death: AUROC = 0.810) and SGA (infectious complications: AUROC = 0.600, death: AUROC = 0.846) in predicting infectious complication and death, but NRS-2002 (0.738) seemed to perform better than SGA (0.552) in predicting non-infectious complications. The risk of malnutrition among patients was high. NRS-2002 and SGA have similar capacity to predict LOS, cost, infectious complications and death, but NRS-2002 performed better in predicting non-infectious complications.

Vegetarian Diet and Cardiometabolic Risk among Asian Indians in the United States

ABSTRACT In the last twenty years products bearing the term ‘natural’ have proliferated in the marketplace. Major food companies have made ‘natural’ claims often with a disclaimer that ‘no artificial preservatives or other such additives have been added’. In the 1970s, the Federal Trade Commission staff developed a two pronged standard encompassing the use of additives and ‘minimal processing’; it was not adopted and there is still no federal standard for the term. However, terms such as ‘natural’ and ‘minimal processing’ continue to be used to describe foods that, contrary to consumers’ expectations and the earlier proposal, are produced with complex processing technologies. As part of the federal legislative mandate to develop standards for production of organic foods, processing standards are also being proposed. It appears that groups developing these standards are not considering the inclusion of a ‘minimal processing’ prong, although there may be a need for this later. In this paper we have studied ...

Red Meat Consumption (Heme Iron Intake) and Risk for Diabetes and Comorbidities

Research studies have shown that plant-based diets confer cardiovascular and metabolic health benefits. Asian Indians (AIs) in the US (who have often followed plant-based diets) have elevated risk for chronic diseases such as diabetes, metabolic syndrome, and obesity suggesting ethnic vulnerability that imply genetic and/or lifestyle causative links. This study explored the association between this ethnic group and diabetes, obesity, and metabolic syndrome after controlling for demographics, acculturation, family history of diabetes, and lifestyle and clinical risk factors. The sample comprised of 1038 randomly selected adult AIs in seven US sites. Prevalence and metabolic syndrome was estimated, and obesity was calculated using the WHO Asian criteria. Multivariate analysis included multinomial logistic regression. The mean age and length of residency in the US were 47 and 18.5 years, respectively. The majority of respondents were vegetarians (62%) and educated. A vegetarian lifestyle was associated with females, food label users, respondents with poor/fair current health status, less acculturated, and those who reported their diet had not changed after coming to the US. Vegetarian status was a protective factor and lowered the risk for diabetes but not for metabolic syndrome and obesity in the regression model. Results provide a firm basis for educational programs.

Integrating the Science and Art of Using Food as Medicine

Purpose of ReviewTo examine the role of red meat consumption, especially heme iron intake, and risk for diabetes and its comorbidities.Recent FindingsStudies consistently show that consumption of red meat has been contributory to a multitude of chronic conditions such as diabetes, CVD, and malignancies. There are various emerging reasons that strengthen this link—from the basic constituents of red meat like the heme iron component, the metabolic reactions that take place after consumption, and finally to the methods used to cook it. The causative links show that even occasional use raises the risk of T2DM.SummaryPrior studies show how nitrites and nitrates in red meat can lead to increased insulin resistance, dysregulated blood glucose levels, and elevated oxidative stress all leading to chronic diseases. With the rise in these preventable chronic diseases, we examine how disease-causing links can be eliminated with appropriate lifestyle choices.