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Suetying Chow

University of California, San Diego

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Publication

Featured researches published by Suetying Chow.

Nucleosides, Nucleotides & Nucleic Acids | 2003

MDPSCL2: a new protecting group for chemoselective synthesis of 2'-O-alkylated guanosines.

Suetying Chow; Ke Wen; Yogesh S. Sanghvi; Emmanuel A. Theodorakis

Abstract An improved strategy for the synthesis of 2′-O-methyl-guanosine (6) and 2′-MOE-guanosine (8) is reported. The regioselectivity of the alkylation was attained using a novel silicon-based protecting group, methylene-bis (diisopropyl-silylchloride) (MDPSCl2, 2). The alkylation proceeded in a chemoselective manner using NaHMDS as the base and MeCl or MOE-Br as the appropriate electrophiles.

Bioorganic & Medicinal Chemistry Letters | 2007

Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Frank Rong; Suetying Chow; Shunqi Yan; Gary Larson; Zhi Hong; Jim Zhen Wu

Bioorganic & Medicinal Chemistry Letters | 2007

Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication

Esmir Gunic; Jean-Luc Girardet; Kanda S. Ramasamy; Vesna Stoisavljevic-Petkov; Suetying Chow; Li-Tain Yeh; Robert Hamatake; Anneke Raney; Zhi Hong

Archive | 2006

Phosphoramidate prodrugs for treatment of viral infection

Esmir Gunic; Suetying Chow; Frank Rong

Archive | 2007

Pyridone sulfonamides and pyridone sulfamides as mek inhibitors

Shunqi Yan; Jean-Michel Vernier; Zhi Hong; Suetying Chow; Yung-Hyo Koh

Bioorganic & Medicinal Chemistry Letters | 2007

6-Hydrazinopurine 2′-methyl ribonucleosides and their 5′-monophosphate prodrugs as potent hepatitis C virus inhibitors

Esmir Gunic; Suetying Chow; Frank Rong; Kanda S. Ramasamy; Anneke Raney; David Y. Li; Jingfan Huang; Robert Hamatake; Zhi Hong; Jean-Luc Girardet

Journal of Organic Chemistry | 2002

Synthesis of 2'-O-Methoxyethylguanosine Using a Novel Silicon-Based Protecting Group

Ke Wen; Suetying Chow; Yogesh S. Sanghvi; Emmanuel A. Theodorakis

Archive | 2004

Quinoxaline derivatives having antiviral activity

Haoyun An; Frank Rong; Jim Zhen Wu; Clayton Harris; Suetying Chow

Bioorganic & Medicinal Chemistry Letters | 2003

Novel synthesis of 2'-O-methylguanosine.

Suetying Chow; Ke Wen; Yogesh S. Sanghvi; Emmanuel A. Theodorakis

Archive | 2007

Pyridonsulfonamide und pyridonsulfamide als mek-hemmer Pyridonsulfonamide and pyridonsulfamide as mek-inhibitors

Yung-Hyo Koh; Zhi Hong; Jean-Michel Vernier; Suetying Chow; Shunqi Yan

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Zhi Hong

Schering-Plough

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Emmanuel A. Theodorakis

University of California

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Esmir Gunic

Valeant Pharmaceuticals

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Yogesh S. Sanghvi

Isis Pharmaceuticals

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Ke Wen

Chinese Academy of Sciences

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Jean-Michel Vernier

Valeant Pharmaceuticals

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Anneke Raney

Valeant Pharmaceuticals

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Jim Zhen Wu

Valeant Pharmaceuticals

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Kanda S. Ramasamy

Isis Pharmaceuticals

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Robert Hamatake

GlaxoSmithKline

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