Sumeet Gairola

A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use.

ETHNOPHARMACOLOGICAL RELEVANCE Jammu & Kashmir (J&K) is a predominantly Himalayan state in the north-western part of India. It has three geographically distinct divisions viz., Jammu, Kashmir and Ladakh, which are immensely rich in their biological and cultural diversity. Medicinal plants are an important element of indigenous medical system of the region. The main goal of the present article is to examine the use of ethnomedicinal plants in three divisions of J&K and to discuss cross-cultural consensus on the use of medicinal plants in these divisions. The article also discusses the gaps in the current state of knowledge on ethnomedicinal plants of the region and gives recommendations for the future studies. MATERIALS AND METHODS Scientific literature on ethnomedicinal field studies conducted in J&K state of India available in the journals, edited books and other scientific databases viz., CAB international, DOAJ, Google Scholar, PubMed, Science direct, SciFinder, Scopus and Web of Science were searched. Only field based ethnomedicinal surveys from last four decades up to December 2013 reporting first hand information on the medicinal plants used to treat human health related ailments by indigenous communities of J&K were included in this study. Venn diagram was used to analyze the cross-cultural consensus on the use of ethnomedicinal plants in the three divisions of J&K. RESULTS A total of 948 plant taxa (923 angiosperms, 12 gymnosperms and 13 pteridophytes) belonging to 129 families, 509 genera, 937 species and 11 varieties have so far been reported to have a traditional medicinal use by indigenous communities of J&K. Asteraceae (60 genera, 132 spp.) was the most frequently used family followed by Fabaceae (32 genera, 50 spp.) and Lamiaceae (27 genera, 55 spp.). 514, 415 and 397 medicinal plants were used in Jammu, Kashmir and Ladakh divisions, respectively. Sixty eight plant taxa were used in all the three divisions, whereas 95 plants were common between Ladakh and Jammu, 127 plants between Ladakh and Kashmir, and 216 plants between Jammu and Kashmir. Maximum numbers of plant taxa were used for treating dermatological problems (321), followed by cold, cough and throat related ailments (250), fever (224), joint and muscle related ailments (215), gastrointestinal disorders (210), urogenital ailments (199), respiratory ailments (151), body pain (135) and gynecological disorders (127). CONCLUSIONS This is the first study from the J&K state, which has examined the medicinal plant use in three divisions of J&K and discussed the promising medicinal plant species with cross-cultural consensus. The analysis of the data suggested that while large numbers of plants are used medicinally in each division, there is a low interregional consensus and high variation between medicinal plants used in these divisions, which is due to both cultural divergence as well as biological distinctness. The issues related to current status of knowledge on medicinal plants used by indigenous communities of J&K have been discussed and some recommendations have been made for future studies on medicinal plants in J&K region.

The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India

ETHNOPHARMACOLOGICAL RELEVANCE Inspite of tremendous advances made in allopathic medical practices, herbs still play an important role in the management of various liver diseases. A large number of plants and formulations have been claimed to have hepatoprotective activity. Jaundice is a symptom, indicative of the malfunctioning of the liver. This paper provides ethnomedicinal information on the plants used to treat jaundice by three important indigenous communities, i.e., nomadic Gujjars, Tharu and Bhoxa of Sub-Himalayan region, Uttarakhand, India. AIMS OF THE STUDY To record herbal preparations used by the studied indigenous communities in treatment of jaundice and discuss hepatoprotective properties of the recorded plants. RESEARCH STRATEGY AND METHODS The traditional knowledge of the studied indigenous communities on herbal preparations used for treating jaundice was collected through structured questionnaire and personal interviews. The interviews were conducted with 91 traditional healers (29 Bhoxa, 35 Tharu and 27 nomadic Gujjars) in Sub-Himalayan region of Uttarakhand, India. More than 250 research papers reporting ethnomedicinal information on the hepatoprotective plants used by various communities from different parts of India were extensively reviewed. RESULTS A total of 40 medicinal plants belonging to 31 families and 38 genera were recorded to be used by the studied communities in 45 formulations as a remedy of jaundice. Bhoxa, nomadic Gujjars and Tharu communities used 15, 23 and 9 plants, respectively. To our knowledge eight plants reported in the present survey viz., Amaranthus spinosus L., Cissampelos pareira L., Ehretia laevis Roxb., Holarrhena pubescens Wall., Ocimum americanum L., Physalis divaricata D. Don, Solanum incanum L. and Trichosanthes cucumerina L. have not been reported earlier as remedy of jaundice in India. Literature review revealed that a total of 214 (belonging to 181 genus and 78 families), 19 (belonging to 18 genus and 12 families) and 14 (belonging to 14 genus and 11 families) plant species are used as internal, external and magico-religious remedies for jaundice, respectively by various communities in different parts of India. Most widely used hepatoprotective plant species for treatment of jaundice in India is Boerhavia diffusa L. followed by Tinospora cordifolia (Willd.) Miers, Saccharum officinarum L., Phyllanthus amarus Schumach. & Thonn., Ricinus communis L., Andrographis paniculata (Burm. f.) Nees., Oroxylum indicum (L.) Kurz, Lawsonia inermis L. and Eclipta prostrata (L.) L. CONCLUSIONS The plants recorded in the present survey have also been discussed in relation to pharmacological studies and hepatoprotective phytoconstituents present in them. Most of the recorded plants have shown hepatoprotective effects on experimental animals in earlier studies but more studies are needed to assess hepatoprotective properties of some recorded medicinal plants viz., Averrhoa carambola L., Ehretia laevis Roxb., Holarrhena pubescens Wall., Mangifera indica L., Ocimum americanum L., Oroxylum indicum (L.) Kurz, Physalis divaricata D. Don, Solanum incanum L., Sphaeranthus senegalensis DC. and Tribulus terrestris L.. The plants enumerated in this study with high number of citations and wider distributions have given some useful leads for further biomedical research. Nevertheless more phytochemical, pharmaceutical and clinical studies are needed to evaluate hepatoprotective properties, efficacy and safety of all the claimed medicinal plants.

Effects of slope aspects on forest compositions, community structures and soil properties in natural temperate forests of Garhwal Himalaya

The present study was undertaken in seven natural forest types of temperate zone (1500 to 3100 m, a.s.l.) of Garhwal Himalaya to understand the effects of slope aspects viz., north-east (NE), north-west (NW), south-east (SE) and south-west (SW), on the forest structure, composition and soil characteristics of each selected forest type. The sample plots in each forest type were laid out by using stratified random approach. The indices i.e., the Importance Value Index, Shannon-Wiener diversity index, Simpson’s concentration of Dominance, Simpson diversity index, Pielou equitability and Margalef species richness index were calculated statistically using standard softwares to elucidate the differences in forest structure and composition of forest types on different slope aspects of the sites. The composite soil samples were taken from each forest stand and the physico-chemical properties of the soil i.e., moisture content (MC), water holding capacity (WHC), pH, organic carbon (OC), phosphorus (P), potassium (K) and available nitrogen (N) were analyzed. The results show that the higher values of total basal cover (74.4 m2·ha−1 in Quercus semecarpifolia forest), Concentration of dominance (0.85 in Pinus roxburghii forest) and Tree diversity (1.81 in Quercus floribunda forest) in the forests were recorded in the northern aspects. MC (40.8% in Quercus leucotrichophora forest), WHC (48.9% in Cupressus torulosa forest), OC (3.8% in Cedrus deodara forest), P (31.9 kg·ha−1 in Quercus leucotrichophora forest) and N (1.0% in Pinus roxburghii forest) had also higher values in the soils of northern aspects. Consequently the higher productivity of the forests was also noticed on the northern aspects.

Ethnomedicinal plants used to treat skin diseases by Tharu community of district Udham Singh Nagar, Uttarakhand, India

ETHNOPHARMACOLOGICAL RELEVANCE Tharu community is the largest primitive indigenous community of the Uttarakhand, India. In this article we have scientifically enumerated medicinal plants and herbal preparations used by the Tharu community to treat various skin diseases, and discussed dermatological properties of these plants in the light of previous ethnomedicinal, microbiological, pharmacological, toxicological, phytochemical and clinical studies. MATERIALS AND METHODS Ethnomedicinal survey was conducted in different villages of Tharu community located in district Udham Singh Nagar, Uttarakhand, India. Ethnomedicinal information on plants used to treat various skin diseases was collected from 122 individuals (93 males and 29 females), including 35 experienced herbal practitioners and 87 local villagers. For each of the recorded plant species the use value (UV) and fidelity level (FL) was calculated. The informant consensus factor (Fic) was also calculated to find out the homogeneity in the information given by the informants. RESULTS A total of 90 plant species belonging to 86 genera and 48 families were used by the Tharu community to treat various skin diseases viz., wounds (38 spp.), boils (32 spp.), cuts (18 spp.), leprosy (11 spp.), eczema (10 spp.), itching (7 spp.), ringworm (5 spp.), burns (4 spp.), leucoderma (4 spp.), cracked heels (2 spp.), dandruff (3 spp.), body infection (2 spp.), chilblains (2 spp.), hair fall (2 spp.) and toes infection (2 spp.). Information on botanical name, family, vernacular name, ailments treated, mode and dose of herbal preparations, UV and FL values are provided for each of the recorded species. According to UV value most preferred plant species used to treat skin diseases by Tharu community was Ricinus communis L. followed by Tridax procumbens (L.) L., Azadirachta indica A. Juss., Ageratum conyzoides and Allium cepa L. CONCLUSIONS The present study has revealed significant information on various medicinal plants used to treat skin diseases by Tharu community. Literature review has confirmed most of the claims made by the Tharu community regarding treatment of various skin diseases by the reported plants. The literature review has also revealed that products from very few of the reported plants are available in market, while most of the reported plants are still under preclinical or clinical trials. There are various known phytochemicals, and antibiotic, antibacterial, antiviral and antifungal agents present in these plants which may be synthesized or transformed to make pharmaceuticals. Some of the reported plants have shown promising results in preclinical trails and there is a need of clinical trials to see their safety and efficacy in treating various skin diseases. These plants may be targeted for development of new medicines, ointments or drugs for the treatment of skin diseases. However further toxicological, preclinical and clinical studies are needed to validate claims about little worked out plant species reported in the present study viz., Sida cordata (Burm. F.) Borss. Waalk., Millettia extensa (Benth.) Baker, Caesulia axillaris Roxb., Ehretia laevis Roxb., Vanda tessellate (Roxb.) Hook. Ex G.Don. and Eualaliopsis binata (Retz.) C.E. Hubb. Further studies on these plants are recommended to assess their potential in development of new skin care products.

Ethnomedicinal plants used for treating epilepsy by indigenous communities of sub-Himalayan region of Uttarakhand, India

ETHNOPHARMACOLOGICAL RELEVANCE Although many plants are claimed to possess anticonvulsant/antiepileptic (AC/AE) properties, but there is very little information available about plants used by various ethnic communities in different parts of India to treat epilepsy, one of the most common disorders of central nervous system (CNS); this communication provides significant ethnomedicinal information on the plants used by indigenous communities: Bhoxa, Tharu and nomadic Gujjars of sub-Himalayan region, Uttarakhand, India to treat epilepsy, so that it could be used as a baseline data for studying chemical constituents and biological activities of these promising plants. AIMS OF THE STUDY To record herbal preparations used by the presently studied communities for treating epilepsy and discuss AC/AE properties of the recorded plants. RESEARCH STRATEGY AND METHODS Ninety one traditional healers (29 Bhoxa, 35 Tharu and 27 nomadic Gujjars) in sub-Himalayan region of Uttarakhand, India were interviewed to collect information on herbal preparations used by them for treating epilepsy. For each recorded species the use value (UV) and fidelity level (FL) was calculated. RESULTS A total of 24 plants belonging to 24 genera and 22 families were used by the presently studied communities in 26 formulations to treat epilepsy. According to FL and UV values, most preferred species for the treatment of epilepsy by Bhoxa community are Ricinus communis L. and Datura stramonium L.; by nomadic Gujjar community are Martynia annua L., Bacopa monnieri (L.) Wettst. and Ricinus communis L.; and by Tharu community are Allium sativum L., Asparagus racemosus Willd. and Achyranthes aspera L. Eight plants viz., Allium sativum L., Boerhavia diffusa L., Cassia fistula L., Clerodendrum viscosum Vent., Datura stramonium L., Inula cappa DC., Oroxylum indicum (L.) Kurz and Pavetta indica L. recorded in the present survey have been reported for the first time in treatment of epilepsy by these indigenous communities in India. Five out of these eight newly reported plants viz., Cassia fistula L., Clerodendrum viscosum Vent., Inula cappa DC., Oroxylum indicum (L.) Kurz and Pavetta indica L. have not been pharmacologically evaluated yet for their possible AC/AE properties. CONCLUSIONS Detailed research on the listed plants and their derivatives may be undertaken to provide new alternative treatments and therapeutic uses for epilepsy or other diseases of CNS. We hope that this article will stimulate further investigations into natural products for new AC/AE agents from the recorded ethnomedicinal plants.

Plants used for treatment of dysentery and diarrhoea by the Bhoxa community of district Dehradun, Uttarakhand, India

ETHNOPHARMACOLOGICAL RELEVANCE Dysentery and diarrhoea are major causes of morbidity and mortality in rural communities of developing world. The Bhoxa community is an important primitive indigenous community of Uttarakhand, India. In this paper we have tried to scientifically enumerate ethnomedicinal plants and herbal preparations used by Bhoxa community to treat dysentery and diarrhoea, and discuss their antidiarrhoeal properties in the light of previous ethnomedicinal, pharmacological, microbiological and phytochemical studies. AIMS OF THE STUDY Torecord plants and herbal preparations used by Bhoxa community of district Dehradun, Uttarakhand, India in treatment of dysentery and diarrhoea, and to discuss antidiarrhoeal and antimicrobial properties of the recorded plants. RESEARCH STRATEGY AND METHODS Ethnomedicinal survey was conducted in different villages of Bhoxa community located in district Dehradun, Uttarakhand, India. Thirty Bhoxa traditional healers were interviewed to collect information on plants used by them for treating dysentery and diarrhoea. For each of the recorded plant species the use value (UV) and fidelity level (FL) was calculated. Detailed literature survey was conducted to summarize ethnomedicinal, pharmacological, microbiological and phytochemical information on the medicinal plants listed in the present study. RESULTS Fifty medicinal plants (45 genera and 30 families) were used by Bhoxa community to treat dysentery and diarrhoea, among which 27 species were used for dysentery, 41 for diarrhoea and 18 for both dysentery and diarrhoea. Three plants viz., Dioscorea bulbifera L., Euphorbia thymifolia L. and Prunus persica (L.) Stokes, recorded in the present survey have been reported for the first time in treatment of dysentery and diarrhoea by any indigenous communities in India. FL and UV values revealed that most preferred species for the treatment of dysentery and diarrhoea by Bhoxa community are Euphorbia hirta L. followed by Holarrhena pubescens Wall., Helicteres isora L. and Cassia fistula L. Eariler pharmacological studies confirmed that 27 of the recorded plants have some proven antidiarrhoeal properties and remaining 23 plants have to be pharmacologically evaluated for their antidiarrhoeal properties. Except 6 plants all the other recorded plants have shown antimicrobial properties in previous microbiological studies. Previous studies have corroborated the ethnomedicinal claims made by the traditional healers of the Bhoxa community. CONCLUSIONS Present study has provided new information on many medicinal plants and their uses. All the three newly reported plants for treatment of dysentery and diarrhoea have not been pharmacologically evaluated yet for their possible antidiarrhoeal properties. Twenty three and 6 plants have not been evaluated pharmacologically and microbiologically, respectively. The present information may serve as a baseline data to initiate further research for discovery of new compounds and biological activities of these potential plants. Further research on these plants may provide some important clues for development of new drugs for dysentery and diarrhoea or other related diseases.

Regeneration dynamics of dominant tree species along an altitudinal gradient in moist temperate valley slopes of the Garhwal Himalaya

The present study was undertaken in moist temperate forest of Mandal-Chopta area in the Garhwal region of Uttarakhand, India. The aim of the present study was to understand the regeneration dynamics of the dominant tree species along an altitudinal gradient in naturally regenerating, restricted access forest. The overall regeneration status was fairly high in the study area. Most of the native canopy and undercanopy dominants had frequent reproduction and expanding populations, which suggests the stability of forest structure/composition and further expansion of dominant species. The overall regeneration of trees in the forest had a greater contribution of middle and understorey species. Because of infrequent reproduction and declining populations of some of the dominant native species viz., Abies pindrow, Alnus nepalensis and Betula alnoides, structural/compositional changes in the future are expected in respective forests dominated by them. Abies pindrow and Taxus baccata need immediate attention by forest managers for their survival in the area. Seedlings were found to be more prone to competition from herb and shrubs than saplings.

Tree species composition and diversity along an altitudinal gradient in moist tropical montane valley slopes of the Garhwal Himalaya, India

The study was conducted along an altitudinal gradient (1500 to 2850 m above sea level) in moist tropical montane valley slopes of the Mandal-Chopta area in the Garhwal region of India. Twelve forest types according to the altitude, slope aspect, and species compositions were selected for the study. The aims of the study were to describe and examine the structure and composition of the tree vegetation along an altitudinal gradient, and to compare the results of the present study with the other forests of Uttarakhand Himalaya growing at similar altitudinal range. High values of stem density and species diversity were recorded in mixed broad-leaved forest types growing between 1600 and 2400 m a.s.l., whereas forest types growing at higher altitudes (>2400 m a.s.l.) had low species richness and stem density. Tree density (tree ha−1) showed positive relationship with species richness and Shannon–Wiener diversity index. Forest types growing at higher altitude (>2400 m a.s.l.) showed geometric dominance-diversity curves. The values of stem density and total basal area in most of the forest types were higher than the earlier reported values from other parts of the Uttarakhand Himalaya.

Forest utilization pattern in relation to socio-economic status of people in Dudhatoli area of Garhwal Himalaya.

ABSTRACT Over the past few decades, the Himalaya has experienced unprecedented land use changes driven by rapid population growth and intensified human activities. Pressure on forests and their products has dramatically increased. Understanding forest products consumption is thus fundamental for assessing human-environment interactions and designing effective conservation policies in the Himalaya. This case-study focused on the relationship between the socio-economic status of the inhabitants, the forest utilization pattern and the anthropogenic pressures on the forest in the Dudhatoli area of Garhwal Himalaya, between 1750 m and 2200 m asl. Agricultural production and labour employment were the main occupation of the villagers in the study area. Approximately 82% (35,48 Quintals/annum/household) of total fuel wood and 78% (39,81 Quintals/annum/household) of the total consumed fodder was extracted from the forest, Dudhatoli forest is thus facing tremendous anthropogenic pressure. A total of 22 forest tree species were recorded to be used for a variety of purposes by the villagers. Anthropogenic pressure was highest in the forests close to the villages, and Quercus species were the most affected. Tree species richness and canopy cover was higher whereas stem density was lower in the undisturbed forests than in forests near the villages.

Moss Flora of Kedarnath Wildlife Sanctuary (KWLS), Garhwal Himalaya, India

Mosses are one of the dominant plant communities at higher elevations in the Himalaya and play an important role in the ecosystem dynamics. The authors assessed the diversity of mosses in the Kedarnath Wildlife Sanctuary (KWLS) of Garhwal Himalaya, India. A total of 113 species of mosses belonging to 65 genera are recorded along with their habitat preference, life strategies, growth forms and pattern of distribution at an altitudinal gradient in KWLS. Seven species of mosses viz., Dicranum orthophylloides Dix., Prionidium setschwanicum (Broth.) Hilp., Funaria microstoma Bruch ex Schimp., Plagiomnium drummondii (Bruch & Schimp.) T. Kop., Aerobryopsis wallichii (Brid.) Fleisch., Barbella turgida Nog. and Thuidium talongense Besch. are recorded for the first time from India. Twelve species of mosses are found new to western Himalaya, which were earlier reported to be endemic to eastern Himalayan region. Fifty two species are new records for Garhwal Himalayan region. Bryaceae (22 spp.) and Bryum (9 spp.) are found to be widely distributed taxa followed by Meteoriaceae (8 genera), Pottiaceae (8 genera) and Dicranaceae (6 genera).