Sun-Kwon Kim

P19.15: Clinical report on the cases of the heterotopic pregnancies treated by selective fetal reduction procedure

the 1st trimester. Group B – the defect was diagnosed in the 2nd trimester. Methods: Monitored period from VII/2006 to VII/2009. Group A: defect diagnosed in the 1st trimester. Due to a positive combined test or finding a structural defect the CVS of the involved foetus was offered. In case of severe choromosomal aberration or defect the transabdominal selective termination (ST) was carried out on a family request. AMC was indicated in the healthy foetus in 16th week of pregnancy. Group B: defect diagnosed in the 2nd trimester. AMC and karyotype were indicated for both foetuses and in the case of severe defect the transabdominal ST was carried out ont the family request. All procedures were performed performed in an outpatient manner. Results: Group A: In 9 cases of double pregnancies an abnormality was diagnosed in 1 foetus. 11.1% was monochorionic twins. Results of the pregnancies – see Table. Group B: In 21 cases of double pregnancies an abnormality was diagnosed in 1 foetus. 23.8% was monochorionic twins. Results of the pregnancies – see Table. Conclusions: Even though the monitored group is limited by an error of small numbers, the risk of a loss of pregnancy after the reduction in the 2nd trimester (9.5%) is in concordance with the data stated in literature. Better results have been reached if the defect was diagnosed in the 1st trimester, then the risk of a pregnancy loss after the selective foeticide has been lower, but not significantly.

P33.05: Clinical study on prenatal diagnosed ovarian cyst

bladder. Severe dilatation of the left renal pelvis was noted with significant caliectasis, thinning of the renal cortex, and hydroureter. Case 2 was an 18 year old G4 P1021 who presented for assessment of fetal growth in the third trimester and was found to have a mass containing echogenic debris in the midline of the lower fetal abdomen. Follow up ultrasounds demonstrated persistence of the mass with progressive bilateral renal and ureteral dilatation. In both cases, postnatal evaluation confirmed the prenatal findings and revealed a diagnosis of imperforate hymen. Both fetuses underwent hymenostomy with subsequent resolution of the mass and improvement in hydronephrosis. Conclusion: Imperforate hymen should be considered as the etiology of renal obstructive disease in female fetuses presenting with a pelvic mass. Postnatal management and hymenostomy resulted in resolution of hydronephrosis.

OP03.11: Normal fetal lung volume using three-dimensional eXtended Imaging Virtual Organ Computer aided AnaLysis (XIVOCAL) method in Korean population

the left lung, and R2 = 0,937 to the total lung volume). The lung volume also proved to be highly related to fetal weight (R2 = 0,905 to the right lung, R2= 0,84to the left lung, and R2 = 0,908 to the total lung volume). The intra-observer variability study was of 0,990 for the right lung, 0,986 for the left lung, and 0,995 for the total lung volume. The value of Cronbach Alfa Coefficient to evaluate the inter-observer variability was 0,975 for the right lung, and 0,962 for the left lung. Conclusion: the fetal lung volume measurement by VOCAL method of 3-dimensional unltrasonography shows good reproducibility and can be utilized to evaluate fetal lung growth.

P05.12: Developmental outcome of prenatally diagnosed agenesis of the corpus callosum

septum pellucidum (SP), hypoplasia of the optic chiasma and nerves, and various types of pituitary dysfunction. The etiology of SOD is unknown. Most cases are sporadic, but a familial occurrence has been noted which raises the possibility of autosomal recessive inheritance. Sonographic demonstration in utero of isolated absence of the SP with central fusion of the frontal horns is a clue to the diagnosis of DSO, which is confirmed after birth with findings of the magnetic resonance imaging (MRI), direct ophthalmoscopy and pituitary hormonal deficiency. Case report: A healthy 28 year-old woman, gravida 2 para 1, was referred at 33 weeks’ gestation to the UNIFESP Fetal Medicine Service on suspicion of fetal ventriculomegaly. Sonographic examination revealed absence of the SP and mild ventriculomegaly. A Fetal MRI confirmed the sonographic findings and showed a probable hypoplasia of the optic nerves. The possibility of DSO was raised. A full-term 3240g male infant was delivered by Cesarean. Postnatal investigation confirmed the diagnosis of SOD with the following findings: RMI showed absence of the SP and mild ventriculomegaly, hypoplasia of the optic nerves by direct ophthamoscopy, and pituitary dysfunction. Currently the child has been followed at the UNIFESP endocrinology and neurology service. Discussion: Absence of the SP is a rare congenital brain malformation and occurs in 2-3 : 100.000 individuals in the general population. It may occur without other brain anomalies, or may be associated with holoprosencephaly, schizencephaly, agenesis of the corpus callosum and DSO. Sonographic demonstration in utero of isolated absence of the SP with central fusion of the frontal horns is a clue to the diagnosis of DSO. However, the diagnosis of SOD is only confirmed with postnatal investigation, with findings of the MRI, direct ophthamoscopy and pituitary hormonal deficiency.