Sung-Hak Jung
CJ Group
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Sung-Hak Jung.
Bioorganic & Medicinal Chemistry Letters | 2003
Euikyung Kim; Hyung-ok Chun; Sung-Hak Jung; Jong Hoon Kim; Jae-Mok Lee; Byung-Chul Suh; Myung Xik Xiang; Chung K Rhee
A new series of catechol hydrazines was synthesized and their structure-activity relationship (SAR) was analyzed for developing an effective phosphodiesterase 4 (PDE4) inhibitor as an anti-asthmatic drug candidate. Among the (E)-Analogues tested using in vitro assays, 5CC showed a strong PDE4 inhibitory activity and a significantly improved rolipram binding profile compared with rolipram, a prototype PDE4 inhibitor. Moreover, from in-vivo asthma model, we observed that (E)-Analogue 5CC had a good efficacy against guinea-pig respiratory tract inflammation and bronchoconstriction, along with a remarkably reduced emetic side effect, compared with rolipram. Conclusively, (E)-Analogue 5CC seems to be a promising candidate for the development of anti-asthmatic PDE4 inhibitors.
Archive | 2003
Il-hwan Cho; Dong-Hyun Ko; Myeong-Yun Chae; Tae-Rho Kim; Kyoung-Rae Kang; Jong-hoon Gongjak Lucky Apt Kim; Sung-Hak Jung; Sang-wook Woncheon Jugong danji Park; Hyung-ok Chun; Hyung-chul Ryu; Ji-young Noh; Hyun Jung Park; Jie-Eun Park; Young-Mee Chung
The Journal of Allergy and Clinical Immunology | 2005
Sung-Hak Jung; M. Moon; W. Park; Hern Ku Lee; Dowan Kim
Archive | 2003
Dong-Kwon Lim; Hyuk-Koo Lee; Hearan Suh; Seong-Hwan Cho; Kwang-Hyeg Lee; Yun-Cheul Kim; Sung-Hak Jung; Sung-Hak Lee; Hyun-Suk Kang; Kyung-Mi Park; Yun-Taek Jung; Jun-Hee Cheon; Choong-Sil Park; Yong-Sik Youn; Young Hoon Kim; Kyu-Jeong Yeon; Myeong-Yun Chae; Hae-Tak Jin
Archive | 2003
Myeong-Yun Chae; Il-Hwan Cho; Hyung-Ok Chun; Young-Mee Chung; Sung-Hak Jung; Kyoung-Rae Kang; Jong Hoon Kim; Tae-Rho Kim; Dong-Hyun Ko; Ji-Young Noh; Hyun Jung Park; Jie-Eun Park; Sang-Wook Park; Hyung-Chul Ryu
Archive | 2003
Seong-Hwan Cho; Yong-Sik Youn; Yun-Taek Jung; Choong-Sil Park; Hyuk-Koo Lee; Kwang-Hyeg Lee; Eun-Ju Jeong; Young Hoon Kim; Hae-Tak Jin; Jun-Hee Cheon; Sung-Hak Lee; Sung-Hak Jung; Dong-Kwon Lim; Kyo-Jeong Yeon; Yun-Cheul Kim; Kyung-Mi Park; Hyun-Suk Kang
Archive | 2003
Il-Hwan Cho; Jee-Woong Lim; Sang-Wook Park; Hyung-Chul Ryu; Ji-Young Noh; Jong Hoon Kim; Myeong-Yun Chae; Sung-Hak Jung; Hyun Jung Park; Kyu-Jeong Yeon; Kyoung-Rae Kang
Archive | 2003
Myeong-Yun Chae; Il-Hwan Cho; Hyung-Ok Chun; Young-Mee Chung; Sung-Hak Jung; Kyoung-Rae Kang; Jong-Hoon Gonjak Lucky Apt. Kim; Tae-Rho Kim; Dong-Hyun Ko; Ji-Young Noh; Hyun Jung Park; Jie-Eun Park; Sang-wook Woncheon Jugong danji Park; Hyung-Chul Ryu
Archive | 2003
Il-Hwan Cho; Dong-Hyun Ko; Myeong-Yun Chae; Tae-Rho Kim; Kyoung-Rae Kang; Jong Hoon Kim; Sung-Hak Jung; Sang-Wook Park; Hyung-Ok Chun; Hyung-Chul Ryu; Ji-Young Noh; Hyun Jung Park; Jie-Eun Park; Young-Mee Chung
Archive | 2003
Il-Hwan Cho; Dong-Hyun Ko; Myeong-Yun Chae; Tae-Rho Kim; Kyoung-Rae Kang; Jong Hoon Kim; Sung-Hak Jung; Sang-Wook Park; Hyung-Ok Chun; Hyung-Chul Ryu; Ji-Young Noh; Hyun Jung Park; Jie-Eun Park; Young-Mee Chung
