Sung-Shik Kim

Surgical Anatomy of the Natural Ostium of the Sphenoid Sinus

Objectives This study was undertaken to measure the distance and the angle between the anterior part of nasal cavity and the natural ostium of the sphenoid sinus. The anatomical location of the natural ostium according to the direction of surgeons operating view toward the anterior wall of the sphenoid sinus was also analyzed.

The effect of botulinum toxin type A injection for intrinsic rhinitis

Botulinum toxin type A (BTA) is known to inhibit the release of acetylcholine from cholinergic nerve endings. Owing to the characteristics of BTA, we thought that it could be used for the treatment of intrinsic rhinitis acting as an anticholinergic drug. In a double-blind placebo-controlled study four units of BTA were injected into the middle turbinate (two units) and inferior turbinate (two units) in each nasal cavity. Rhinorrhoea, nasal obstruction, and sneezing were recorded in a symptom diary on the basis of a scale of 5 and the number of paper tissues used per day was also recorded for 24 weeks. Rhinorrhoea was significantly diminished in severity (24.1-41.5 per cent reduction) and paper tissue use (54.3 per cent reduction) in the BTA group compared with the placebo group. This effect could be maintained for four weeks. Sneezing and nasal stuffiness were not affected by BTA. These results suggest that BTA can be used to treat rhinorrhoea in intrinsic rhinitis patients, however, the effective period is short.

Expression of MUC5AC mRNA in the Goblet Cells of Human Nasal Mucosa

Objectives/Hypothesis Mucus hypersecretion is a common feature in chronic sinusitis with polyps. Because mucus hypersecretion is commonly accompanied by goblet cell hyperplasia, it is important to identify which mucin gene mRNAs are expressed in the goblet cells of the surface epithelium in the human airway. This study aims to investigate the pattern of expression of MUC5AC messenger RNA (mRNA) in the goblet cells of human nasal mucosa.

Creation of Large Maxillary Sinus Ostium: A Modified Antrostomy Technique Removing Palatine Bone for Improved Patency

INTRODUCTION Chronic maxillary sinusitis is a common disease that used to be frequently treated with Caldwell-Luc’s operation by removing all the mucosa within the sinus and making a nasoantral window in the central third of the inferior meatus. However, since the concept of functional sinus surgery and optical aids such as endoscopes and surgical microscopes have been introduced, more precise excision of pathologic lesions under a clear view has become popular. It is important to make an opening on the medial wall of the maxillary sinus and to keep it open for its continuous ventilation and drainage under the concept of conservative surgery, removing only the pathologic mucosa of a chronic maxillary sinusitis. There have been two main types of surgical technique for maintaining or promoting ventilation of diseased maxillary sinuses. One is inferior meatal antrostomy (IMA), the making of an artificial opening on the medial wall of the maxillary sinus through the inferior meatus. The other is middle meatal antrostomy (MMA), the widening of the natural ostium of the maxillary sinus after removing the uncinate process and part of the bulla ethmoidalis through the middle meatus. Generally, MMA is accepted to be more effective than IMA. Mann et a1.l reported spontaneous closure in 29% of cases 2 years after performing IMA, and Lund2 reported spontaneous closure of 45% after 27 months’ follow-up. Reck3 reported that 25% of cases undergoing IMA revealed spontaneous closure of artificially created ostium. He also stated that there is no significant correlation