Sunyoung Lee
Chungnam National University
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Publication
Featured researches published by Sunyoung Lee.
World Journal of Gastrointestinal Oncology | 2013
Min Su Kim; Young-Joo Jin; Jin-Woo Lee; Jung-Il Lee; Young Soo Kim; Sunyoung Lee; Myoung Hun Chae
Hepatocellular carcinoma (HCC) is the fifth most common malignant disease worldwide, and curative treatment remains difficult because the majority of cases are diagnosed in the advanced stage. Sorafenib is the only known effective systemic treatment, but patients rarely achieve complete remission (CR). A 66-year-old man with a history of alcoholic liver cirrhosis with a diagnosis of advanced HCC, was initially treated with transarterial chemoembolization on four occasions. However, the disease progressed with portal vein thrombosis. Therefore, sorafenib was started, and 4 mo later, the patient achieved CR. The treatment was continued for 12 mo, and CR was maintained up to 4 mo after sorafenib discontinuation.
Advances in Experimental Medicine and Biology | 2009
Dalwoong Choi; Sun Ju Kim; Do Young Kwon; Sunyoung Lee; Young Chul Kim
We examined the effect of taurine depletion on hepatic sulfur-containing amino acid metabolism and carbon tetrachloride-induced acute liver injury. Mice were supplemented with beta-alanine (3%) in drinking water for one week. beta-Alanine intake significantly reduced hepatic taurine levels, but did not influence S-adenosylmethionine, S-adenosylhomocysteine, glutathione levels or methionine adenosyltransferase activity in liver. However, hepatic cysteine levels were significantly elevated by beta-alanine administration. Hepatotoxicity caused by carbon tetrachloride (50 microl/kg, ip) in mice fed beta-alanine was decreased, as determined by changes in serum aspartate aminotransferase, alanine aminotransferase and sorbitol dehydrogenase activities. Hepatic glutathione and taurine levels after a carbon tetrachloride challenge were markedly increased by beta-alanine exposure. The results suggest that enhanced availability of cysteine for synthesis of glutathione and/or taurine may account for the hepatoprotective effects of beta-alanine against carbon tetrachloride-induced acute liver injury.
International Journal of Rheumatic Diseases | 2016
In Seol Yoo; Sunyoung Lee; Chan Keol Park; Jeong Chan Lee; Young Kim; Su Jin Yoo; Seung Cheol Shim; Yoon Seok Choi; Young Lee; Seong Wook Kang
There is growing evidence that cold‐inducible RNA‐binding protein (CIRP) promotes inflammatory responses. This study investigated the relationship between CIRP and rheumatoid arthritis (RA).
Journal of Microbiology and Biotechnology | 2001
Kim Soo Yeon; Young Min Lee; Sunyoung Lee; Yeon Sook Lee; Jeong Hwan Kim; Cheol Ahn; Byung Cheol Kang; Geun-Eog Ji
Archive | 2016
SeungJune Yi; Sunyoung Lee
Annals of Dermatology | 1996
Sunyoung Lee; Kyung Pyo Han; Kyu Chul Choi; Young Kyoon Kim
Archive | 2016
Sunyoung Lee; Seung-June Yi
Archive | 2016
Seung-June Yi; Sunyoung Lee; Jaewook Lee
Archive | 2016
Sunyoung Lee; Seung-June Yi
Archive | 2016
Sunyoung Lee; Seung-June Yi