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Susan Hahn

Ipsen

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Publication

Featured researches published by Susan Hahn.

Cancer Research | 2008

AR47A6.4.2, a naked monoclonal antibody targeting Trop-2, exhibits anti-tumor efficacy in multiple human cancer models as a monotherapeutic agent and demonstrates efficacy in combination therapy

Amandine Truong; Ningping Feng; Daad Sayegh; Baldwin Mak; Susan Hahn; Daniel S. Pereira; David S. F. Young

Molecular Cancer Therapeutics | 2007

AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models

Baldwin Mak; Fortunata McConkey; Ningping Feng; Kevin O'Reilly; Philip G. Kasprzyk; Daniel Rubinstein; Susan Hahn; Daniel Pereira; Helen P. Findlay; David S. Young

Journal of Clinical Oncology | 2008

Human chimeric anti-CD44 antibody ARH460–16–2 binds leukemic cells and malignant plasma cells

T. Guillaume; N. Robillard; H. Avet-Loiseau; J. Delaunay; J. L. Harousseau; Susan Hahn; L. A. da Cruz; Daniel S. Pereira; D. B. Rubinstein; D.S. Young

Journal of Clinical Oncology | 2008

Clinical development of huARH460-16-2: A therapeutic antibody targeting the CD44 cancer stem cell antigen on high-incidence adenocarcinomas

Susan Hahn; L. A. da Cruz; Ashwani K. Gupta; B.C. Mak; L. Popp; Daniel S. Pereira; D. B. Rubinstein; D.S. Young

Molecular Cancer Therapeutics | 2007

AR47A6.4.2, a functional naked monoclonal antibody targeting Trop-2, demonstrates in vivo efficacy in human pancreatic, colon, breast and prostate cancer models

Amandine Truong; Ningping Feng; Daad Sayegh; Baldwin Mak; Kevin O'Reilly; Sui-Wah Fung; Nives Ceric; Susan Hahn; Daniel S. Pereira; Helen P. Findlay; David S. Young

Ejc Supplements | 2008

371 POSTER Toxicology and pharmacokinetics of humanized AR47A6.4.2, the first unconjugated therapeutic monoclonal antibody targeting TROP-2

N. Chouinard; Susan Hahn; A.H.L. Truong; L. Popp; X. Wang; D. Sayegh; V. Harris; B.C. Mak; D.B. Rubinstein; D.S. Young

Ejc Supplements | 2008

538 POSTER ARH460-16-2, targeting the CD44 cancer stem cell marker, uses multiple mechanisms to achieve its therapeutic anti-cancer effects

L.A.G. da Cruz; K. O'Reilly; Fortunata McConkey; X.W. Wang; T. Antoshchenko; N. Aziz; Ashwani K. Gupta; Susan Hahn; Daniel S. Pereira; D.S. Young

Ejc Supplements | 2008

543 POSTER Location… location… location: hitting the functional epitope within the target is essential for anti-cancer antibody therapeutics

B.C. Mak; A.H.L. Truong; Ningping Feng; L.A.G. da Cruz; B.S. Mistry; Sui-Wah Fung; T. Perez; Susan Hahn; Daniel S. Pereira; D.S. Young

Molecular Cancer Therapeutics | 2007

A monoclonal antibody targeting melanoma-associated chondroitin sulfate proteoglycan demonstrates antitumor activity in human melanoma, ovarian and breast cancer models.

Ashwani K. Gupta; Alison L. Ferry; Daad Sayegh; Luis da Cruz; Ningping Feng; Susan Hahn; Daniel S. Pereira; Helen P. Findlay; David S. F. Young

Molecular Cancer Therapeutics | 2007

Toxicology and pharmacokinetics of chimeric ARH460-16-2, a therapeutic monoclonal antibody targeting CD44

Susan Hahn; Luis A. G. Dacruz; Nadine Chouinard; Daniel S. Pereira; Daniel B. Rubinstein; David S. F. Young

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Collaboration

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Daniel S. Pereira

Astellas Pharma

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Ningping Feng

Ipsen

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D.S. Young

University of Hong Kong

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Helen P. Findlay

Ipsen

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Daad Sayegh

University of Hong Kong

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Ashwani K. Gupta

University Health Network

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David S. F. Young

OSI Pharmaceuticals

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Baldwin Mak

Ipsen

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Alison L. Ferry

Hoffmann-La Roche

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David S. Young

Ipsen

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