Susan J. Hartmann
Pfizer
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Publication
Featured researches published by Susan J. Hartmann.
Bioorganic & Medicinal Chemistry Letters | 2010
Jane L. Wang; Jeffery S Carter; James R. Kiefer; Ravi G. Kurumbail; Jennifer L. Pawlitz; David Brown; Susan J. Hartmann; Matthew J. Graneto; Karen Seibert; John J. Talley
In this manuscript, we report the discovery of the substituted 2-trifluoromethyl-2H-benzopyran-3-carboxylic acids as a novel series of potent and selective cyclooxygenase-2 (COX-2) inhibitors. 5c-(S) (SD-8381) was advanced into clinical studies due to its superior in vivo potency. The high plasma protein binding (>99% bound) of 5c-(S) has resulted in a surprisingly long human half life t(1/2)=360 h.
Bioorganic & Medicinal Chemistry Letters | 2007
John I. Trujillo; Marvin Jay Meyers; David R. Anderson; Shridhar Hegde; Matthew W. Mahoney; William F. Vernier; Ingrid P. Buchler; Kun K. Wu; Syaluan Yang; Susan J. Hartmann; David B. Reitz
Archive | 2007
Balekudru Devadas; Susan J. Hartmann; Richard Frederick Heier; Kevin D. Jerome; Stephen A. Kolodziej; John Paul Mathias; Monica B. Norton; Michele A. Promo; Paul V. Rucker; Shaun R. Selness
Bioorganic & Medicinal Chemistry Letters | 2009
John I. Trujillo; Marvin Jay Meyers; David R. Anderson; Shridhar Hegde; Matthew W. Mahoney; William F. Vernier; Ingrid P. Buchler; Kun K. Wu; Syaulan Yang; Susan J. Hartmann; David B. Reitz
Archive | 2010
Brad A. Acker; Susan J. Hartmann; Horng-Chih Huang; Eric Jon Jacobsen; Michele A. Promo; Sergey Gregory Wolfson; Jin Xie
Archive | 2007
Balekudru Devadas; Susan J. Hartmann; Richard Frederick Heier; Kevin D. Jerome; Stephen A. Kolodziej; John Paul Mathias; Monica B. Norton; Michele A. Promo; Paul V. Rucker; Shaun R. Selness
Archive | 2000
David L. Brown; Jeffery S Carter; Mark G. Obukowicz; Balekudru Devadas; John J. Talley; Matthew J. Graneto; Stephen R Bertenshaw; Donald J Rogier; Srinivasan Nagarajan; Cathleen E. Hanau; Susan J. Hartmann; Cindy L. Ludwig; Suzanne Metz
Archive | 1999
Matthew J. Graneto; Susan J. Hartmann; Suzanne Metz; John J. Talley; Michael L. Vazquez; David L. Brown; Richard M. Weier; Michael A. Stealey; Xiangdong Xu
Archive | 1999
Michael L. Vazquez; John E. Baldus; Kevin D. Jerome; Yi Yu; John K. Walker; Syaulan Yang; Michael Clare; Suzanne Metz; Shaun R. Selness; Xiangdong Xu; Win Naing; Ashok Anantanarayan; Paul W. Collins; Joyce Z. Crich; Rajesh Devraj; Daniel L. Flynn; Lifeng Geng; Matthew J. Graneto; Cathleen E. Hanau; Gunnar J. Hanson; Susan J. Hartmann; Michael Hepperle; He Huang; Ish K. Khanna; Francis J. Koszyk; Shuyuan Liao; Richard A. Partis; Thao D. Perry; Shashidhar N. Rao; Michael S. South
Archive | 1999
Ashok Anantanarayan; John E. Baldus; Michael Clare; Paul W. Collins; Joyce Z. Crich; Rajesh Devraj; Daniel L. Flynn; Lifeng Geng; Matthew J. Graneto; Cathleen E. Hanau; Gunnar J. Hanson; Susan J. Hartmann; Michael Hepperle; He Huang; Kevin D. Jerome; Ish K. Khanna; Francis J. Koszyk; Shuyuan Liao; Suzanne Metz; Win Naing; Richard A. Partis; Thao D. Perry; Shashidhar N. Rao; Shaun R. Selness; Michael S. South; Michael A. Stealey; John J. Talley; Michael L. Vazquez; John K. Walker; Richard M. Weier
