Sven Englund

Studies of the Metabolism of Mn54 in Some Endocrine and Reproductive Organs in the Female Mouse

BS>In adult mice injected subcutaneously with Mn/sup 54/Cl/sub 2/ the reproductive and endocrine organs and the hemispheres of the cerebrum were examined regarding the Mn concentration, exchangeable Mn, biological half life, turnover rate, and metabolized amount (Mn/g/day). Manganese was found to reach a very high concentration and to have a short biological half life in the thyroid compared with the other endocrine and reproductive organs examined. The cerebral hemispheres showed a low concentration and a long biological half life. The concentration of Mn was about equal in all the reproductive organs studied, but was slightly higher in the corpus uteri and the tubes than in the cervix and vagina. The metabolism of Mn did not vary to any large extent among these organs, but they showed considerable differences from the cerebrum. (BBB)

Accidental Injury to the Ureters and the Bladder in Gynæcological Surgery

The accidental injuries of the ureters and the bladder are the most distressing complications of gynzcological surgery. The gynacologists in general are usually unfamiliar with these lesions and lack experience in handling these disturbing operative accidents. This seems to indicate the necessity for the gynacologists in general to know the principal measures to be undertaken.

Autoradiographic Measurements on the Unfertilized Rabbit Ovum and Periovular Granulosa Tissue

111 l)re\-ious 1)apers (Otlel , lat l , 1952. a, I ) ; Ot1el)latl and > I a g n u s s c ~ n , 1954) i t was indicated, that 1’:“ given as inorganic orthophoq~liate intravenously t o ralhits 2 hours Ijefore death entered the cytoplasm of the unfertilized raldlit ovum only to a small degree, compared to the adjacent granulosa cells. Here a11 attempt is made to estimate quantitatively the concentrations of in these structures.

An autoradiographic study of the incorporation of S35 in the urinary bladder of the female mouse following administration of radiosulphate.

An autoradiographic study of the urinary bladder of the mouse with ligated ureters following subcutaneous administration of radiosulphate showed a slight S35 uptake in bladder epithelium, a high uptake in the subepithelial tissue of the mucosa and a slight to moderate uptake in the bladder wall. The absorption through the bladder mucosa in animals with intact ureters was negligible. Oestrogen and progesterone did not influence the uptake of S35 in spayed mice.

Studies on the Uptake of Radioactive Phosphate in Ovarian Follicles of Different Size in the Rabbit

The tiptake of radioactive phosphate in ovarian follicles has I)wn tlemonstratetl antl measured in previous papers (0 d e b 1 ad , I g j I , 1052; B l o c k , M a g n u s s o n , and O t l e b l a d , 1953). I t was pointed out briefly that smaller follicles (except primordial follicles) usually took up more radiophosphate than larger follicles. This prolkrn will be treated in some detail i n the present paper.

An autoradiographic study with radioactive phosphorus of artificial corpora lutea in the rabbit.

As early as 1939 it was shown by B u l l i a r d , G r u n d l a n d & M o u s s a, using autoradiography, that the corpus Iuteum accumulates large amounts of P32, which was ascribed to its high content of phospholipids. The accumulation was most pronounced in the zones of rapid growth. In a report by O d e b l a d (1951, I) it was indicated, that the various stages of development of the corpus luteum were accompanied by characteristic autoradiographic pictures. These preliminary results have been investigated more thoroughly in this article.