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Archive | 2016

Mindfulness Meditation for Chronic Pain: A Systematic Review

Margaret A Maglione; Susanne Hempel; Alicia Ruelaz Maher; Eric Apaydin; Brett Ewing; Lara Hilton; Lea Xenakis; Roberta Shanman; Sydne J Newberry; Benjamin Colaiaco; Melony E. Sorbero

This document and trademark(s) contained herein are protected by law. This representation of RAND intellectual property is provided for noncommercial use only. Unauthorized posting of this publication online is prohibited. Permission is given to duplicate this document for personal use only, as long as it is unaltered and complete. Permission is required from RAND to reproduce, or reuse in another form, any of its research documents for commercial use. For information on reprint and linking permissions, please visit The RAND Corporation is a research organization that develops solutions to public policy challenges to help make communities throughout the world safer and more secure, healthier and more prosperous. RAND is nonprofit, nonpartisan, and committed to the public interest. RANDs publications do not necessarily reflect the opinions of its research clients and sponsors. R® is a registered trademark. iii Preface The Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury is interested in determining the efficacy and comparative effectiveness of integrative medicine approaches for several health conditions. This systematic review assesses the safety and efficacy of mindfulness meditation as an intervention to alleviate chronic pain. The review will be of interest to military health policymakers and practitioners, civilian health care providers, and policymakers, payers, and patients. None of the authors has any conflicts of interest to declare. Abstract This systematic review synthesized evidence on mindfulness meditation interventions for the treatment of chronic pain (PROSPERO 2015:CRD42015025052). In June 2015, we searched four electronic databases, as well as bibliographies of existing systematic reviews, to identify randomized controlled trials (RCTs) testing the efficacy and safety of mindfulness to treat adults with chronic pain. Two independent reviewers screened identified literature using predetermined eligibility criteria, abstracted study-level information, and assessed the quality of included studies. Outcomes of interest included changes in pain symptoms, use of analgesics, health-related quality of life, and adverse events. Efficacy meta-analyses used the Hartung-Knapp-Sidik-Jonkman method for random-effects models. The quality of evidence was assessed using the GRADE approach. In total, 28 RCTs met inclusion criteria; three of these RCTs reported on safety. Interventions ranged in length from three to 12 weeks, and the median duration was eight weeks. We found low quality evidence (due to substantial unexplained heterogeneity among studies) that mindfulness meditation is associated with a small decrease in pain compared with control in 24


Evidence report/technology assessment | 2011

Safety of Probiotics to Reduce Risk and Prevent or Treat Disease

Susanne Hempel; Sydne J Newberry; Alicia Ruelaz; Zhen Wang; Jeremy N. V. Miles; Marika J Suttorp; Breanne Johnsen; Roberta Shanman; Wendelin Slusser; Ning Fu; Alex Smith; Beth Roth; Joanna Polak; Aneesa Motala; Tanja Perry; Paul G Shekelle


Evidence report/technology assessment (Summary) | 2004

Effects of omega-3 fatty acids on lipids and glycemic control in type II diabetes and the metabolic syndrome and on inflammatory bowel disease, rheumatoid arthritis, renal disease, systemic lupus erythematosus, and osteoporosis.

Catherine H. MacLean; Walter Mojica; Sally C Morton; James Pencharz; R Hasenfeld Garland; Wenli Tu; Sydne J Newberry; Lara Jungvig; Jennifer M. Grossman; Puja P. Khanna; Shannon Rhodes; Paul G Shekelle


Evidence Report/Technology Assessment | 2008

Bariatric surgery in women of reproductive age: special concerns for pregnancy.

Paul G Shekelle; Sydne J Newberry; Margaret Maglione; Zhaoping Li; Irina Yermilov; Lara Hilton; Marika J Suttorp; Melinda Maggard; Jason Carter; Carlo Tringale; Susan Chen


Health Affairs | 2005

Identifying Potential Health Care Innovations for the Future Elderly

Paul G. Shekelle; Eduardo Ortiz; Sydne J Newberry; Michael W. Rich; Shannon Rhodes; Robert H. Brook; Dana P. Goldman


Archive | 2012

Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report

Carolyn J. Crandall; Sydne J Newberry; Allison Diamant; Yee-Wei Lim; Marika J Suttorp; Aneesa Motala; Brett Ewing; Beth Roth; Roberta Shanman; Martha Timmer; Paul G Shekelle


Archive | 2009

Results and Conclusion

Paul G Shekelle; Sydne J Newberry; Margaret Maglione; Roberta Shanman; Breanne Johnsen; Jason Carter; Aneesa Motala; Ben Hulley; Zhen Wang; Dena M. Bravata; Michael Chen; Jennifer Grossman


Archive | 2014

Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update)

Sydne J Newberry; Mei Chung; Paul G Shekelle; Marika Suttorp Booth; Jodi L Liu; Alicia Ruelaz Maher; Aneesa Motala; Mike Cui; Tanja Perry; Roberta Shanman; Ethan M Balk


Evidence report/technology assessment | 2012

Allocation of scarce resources during mass casualty events.

Justin W. Timbie; Jeanne S. Ringel; D. Steven Fox; Daniel A. Waxman; Francesca Pillemer; Christine Carey; Melinda Moore; Veena Karir; Tiffani J Johnson; Neema Iyer; Jianhui Hu; Roberta Shanman; Jody Larkin; Martha Timmer; Aneesa Motala; Tanja Perry; Sydne J Newberry; Arthur L. Kellermann


Archive | 2011

Subject Matter Experts

Paul G Shekelle; Sydne J Newberry; Helen Wu; Marika J Suttorp; Aneesa Motala; Yee-Wei Lim; Ethan M Balk; Mei Chung; Winifred W Yu; Jounghee Lee; James M Gaylor; David Moher; Mohammed T Ansari; Rebecca Skidmore; Chantelle Garritty

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Paul G Shekelle

VA Palo Alto Healthcare System

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Martha Timmer

University of California

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Yee-Wei Lim

National University of Singapore

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