Syed F. Ali

Stereoselective synthesis of hydroxylated bifenthrin isomers

Abstract Two isomeric, hydroxylated derivatives of the potent insecticide/acaricide bifenthrin were prepared from a common precursor. A high degree of control over the relative stereochemistry at all three stereogenic centers was achieved by closure of the C1-C3 bond of the cyclopropane ring using a judicious choice of ring closure substrates.