Sylvia Kirchengast

Body composition characteristics are associated with the bone density of the proximal femur end in middle- and old-aged women and men

OBJECTIVES In the present study the associations between bone density of the proximal femur end and weight status, fat distribution patterns (FDI) and body composition parameters i.e. amount of body fat and lean body mass were tested in a sample of old aged women and men. METHODS In 77 healthy women ranging in age from 60 to 92 years (x=71.8 years) and 62 healthy men ranging in age from 60 to 86 years (x=71.5 years) the bone mineral density (BMD of the proximal femur end and the body composition parameters absolute fat mass, relative fat mass, lean body mass and bone mineral content were estimated by dual energy X-ray absorptiometry. Additionally, the weight status (body mass index, BMI) and the FDI were calculated. The bone density of the proximal femur end was correlated with the absolute fat mass and the lean body mass as well as with the BMI and the FDI. RESULTS BMD correlated in females significantly positively with parameters of body composition, in males no significant correlations between fat mass (absolute and relative) and BMD as well as BMD/stature was found. Furthermore, it was shown that the weight status (BMI; r(2)=0.13, P<0.0003 in males and r(2)=0.27, P<0.000 in females), and the lean body mass (r(2)=0.21, P<0.001 in males, r(2)=0.36, P<0.004 in females) were associated significantly positively with the BMD of the proximal femur end in both sexes. The absolute fat mass had a significant impact on BMD in the female subsample only (r(2)=0.24, P<0.000). CONCLUSIONS A lower weight status and a low amount of lean body mass, indicating not only lack of biomechanical forces of the proximal femur end, but also a lack of physical activity can be assumed to be associated increased bone loss and the development of osteoporosis in both sexes. An association between low amount of fat tissue and decreased BMD was especially found in women and may be due to the reduced conversion rates from androgens to estrogens in a low amount of fat tissue.

Gender differences in health-related quality of life among healthy aged and old-aged austrians: Cross-sectional analysis

BACKGROUND Although they experience lower mortality rates and lower rates of several chronic diseases than do their male counterparts, aging women are more likely to experience functional impairment in mobility and a general diminished health-related quality of life (HRQoL). The determinants of these gender differences have been the subject of controversy. OBJECTIVE This study analyzed gender differences in HRQoL in relation to social and biomedical factors such as age, marital status, educational level, and living arrangements. METHODS Participants were recruited via snowball sampling. All were healthy and lived independently in private homes. Data were obtained from personal interviews, based on a 30-item questionnaire, in the private homes of the participants. Additionally, HRQoL was assessed by means of the abbreviated version of the World Health Organization Quality of Life (WHOQOL-BREF) 26-item questionnaire, which contains 1 general health item, 1 general QoL item, and 24 specific items covering 4 broad domains: physical (DOM I), psychological (DOM II), social (DOM III), and environmental (DOM IV). RESULTS The participants (98 women, 62 men) enrolled in the study ranged in age from 57 to 95 years (mean [SD] age: 71.8 [8.6] years). The younger age group (aged 57-70 years) comprised 54 women and 25 men, and the older age group (aged >70 years) comprised 44 women and 37 men. Women aged < or =70 years rated their health and QoL significantly higher than did men in the same age group (P = 0.02). These women rated physical capacity (DOM I), social relationships (DOM III), and environment (DOM IV) higher, but not statistically significantly different, than did same-aged men. Women and men exhibited nearly identical psychological health (DOM II) values. Physical capacity (DOM I) differed significantly between women and men aged >70 years (P = 0.03). Women aged >70 years rated their QoL lower than their male counterparts did, although not significantly so. These women depended more on medical treatment, felt significantly less safe in everyday life (P = 0.03), and were less satisfied with themselves. The results of the multiple regression analyses suggest that gender may have a significant impact on general QoL for both age groups (P < 0.01 for the younger age group; P > 0.04 for the older age group). In these analyses, gender also had a significant impact on 2 domains, physical capacity and social relationships (P < 0.02 for both domains), among the participants of the younger age group. CONCLUSION Depending on the age group (< or =70 vs >70 years) in this small sample of Austrian women and men, gender influenced HRQoL.

Maternal prepregnancy weight status and pregnancy weight gain as major determinants for newborn weight and size.

The impact of maternal anthropometric characteristics, above all prepregnancy weight status and pregnancy weight gain, on newborn size was tested using 10,240 single births in the University Hospital of Vienna, Austria. Highly significant relations between maternal prepregnancy weight status and newborn size were observed. With higher maternal prepregnancy body mass index, higher birthweight, length, head circumference, acromial circumference and fronto occipitalis diameter occurred. Furthermore the incidence of low weight newborns (< 2500 g) was significantly higher in underweight women than in normal weight, overweight and obese women. Although the pregnancy weight gain was significantly higher in underweight women than in normal weight, this higher pregnancy weight gain was not able to compensate for the negative impact of poor weight status before pregnancy. These results indicate that even in a highly developed country such as Austria, where starvation is a nearly unknown problem and the medical and social system are well developed, a poor maternal weight status is a risk factor for growth retarded and low weight births.

Physiological Arousal for Companion Dogs Working With Their Owners in Animal-Assisted Activities and Animal-Assisted Therapy

This study investigated the physiological reactions of companion dogs (Canis familiaris) used in animal-assisted activities and animal-assisted therapy by measuring salivary cortisol concentrations. The dog caregivers (owners) collected saliva samples (a) at 3 control days without therapeutic work, (b) directly before and after each therapeutic session during 3 consecutive months, and (c) again at 3 control days without therapeutic work. The study used an enzyme immunoassay to analyze the samples. Cortisol concentrations were significantly higher during therapy days than on control days. Dogs working during the first half of the day produced higher cortisol concentrations after therapeutic sessions than before, whereas dogs working in the afternoon produced lower cortisol concentrations. Cortisol concentrations were higher in short sessions than in long ones and increased relative to the number of therapeutic sessions done during the sampling period. The results indicate that therapeutic work was physiologically arousing for the dogs in this study. Whether these physiological responses are indicative of potentially negative stress or of positive excitement remains an open question.

To be an immigrant: a risk factor for developing overweight and obesity during childhood and adolescence?

Childhood overweight and obesity, especially among migrant children, are current health problems in several European countries. In the present study the prevalence of overweight and obesity among migrant children from Turkey and the former Yugoslavia was documented and compared with that of Austrian children in Vienna. Anthropometric data from 1,786 children were collected at the ages of 6, 10 and 15 years. Body mass was estimated by means of the body mass index and percentile curves were used to determine weight status. The prevalence of overweight and obesity was found to be significantly higher among migrant children. Children and adolescents from the former Yugoslavia and Turkish girls exhibited especially high rates of overweight and obesity. Biosocial and cultural factors are discussed as causes of these observations.

Effect of percutaneous androgen replacement therapy on body composition and body weight in postmenopausal women

OBJECTIVES This study was carried out to assess the effect of topical androgen replacement therapy on body weight, body composition and fat distribution in postmenopausal women. METHODS 39 healthy postmenopausal women (51.4 +/- 2.24 years), with increasing body weight, were prospectively studied for 6 months. Body composition (fat mass, kg, %) was measured by means of dual-energy X-ray absorptiometry (DXA). Hormonal and lipid parameters were also measured. Subjects were divided into two groups. An androgen gel (group A) or placebo gel (group P) was topically administered to the abdominal and gluteo-femoral regions. DXA was performed before commencement of topical treatment and after 6 months. RESULTS A highly significant total body weight reduction was found in group A (68.0 +/- 13.1 to 65.4 +/- 11.8 kg). Abdominal fat (37.3 +/- 11.2 to 35.1 +/- 9.7%), gluteo-femoral fat (46.3 +/- 6.6 to 45.4 +/- 7.7%), total body fat (38.2 +/- 7.9 to 36.1 +/- 8.6%) and BMI (24.8 +/- 4.3 to 23.7 +/- 3.8) were also found to have decreased significantly in this group. No significant reduction in body weight (kg) and body fat (%) could be measured in the placebo group. No influence on lipid parameters was found although total testosterone increased significantly in group A (0.29 +/- 0.24 to 0.72 +/- 0.17 ng/ml). CONCLUSIONS Topically applied androgen is capable of reducing abdominal fat accumulations as well as total body weight in postmenopausal women with unexplained weight gain. In contrast to systemic androgen application, topical administration has no effect on the lipid profile. Gluteal fat, however, is less effectively influenced by androgens.

Decreased sexual interest and its relationship to body build in postmenopausal women

OBJECTIVES The relationship between body build, androgen levels and changes in sexual interest after menopause was investigated in 171 postmenopausal women from Vienna, Austria. METHODS All women were interviewed using a structured questionnaire. Body build was determined by employing five absolute body dimensions and four anthropometric indices. RESULTS Body weight, as well as the amount of subcutaneous centripetal fat (such as in the chest, waist and hip region), were statistically significantly related to the degree of reduced sexual interest. Corpulent and heavy women suffered far more frequently from a severe decrease in sexual interest after menopause. Statistically significant associations between androgen levels and decrease in sexual interest could not be demonstrated. CONCLUSIONS Reduced sexual interest is associated with a kind of body type not corresponding to the culture-specific beauty ideals of our society, first of all evident in women whose menopause occurred relatively early.

Dog handlers' and dogs' emotional and cortisol secretion responses associated with animal-assisted therapy sessions

The study investigated 13 dog handlers and 18 companion dogs (Canis familiaris) working as teams in nonhuman animal-assisted service. The handlers described in questionnaires what emotions they chose to associate with their daily life and therapeutic work. They described their emotional condition before and after therapeutic sessions, giving analogous descriptions for their dogs. Handlers collected saliva samples from themselves and their dogs (6 non-therapeutic control days) during 3 months of therapeutic work) to measure cortisol concentrations using an enzyme-immunoassay. Handlers chose different emotions from the questionnaires for themselves and their dogs, differing from the cortisol sampling results. Handlers and dogs had increased cortisol concentrations on therapy days compared to control days. Handlers had significantly higher concentrations immediately before therapeutic sessions. In handlers, cortisol concentrations increased steadily with the duration of sessions; in dogs, with the number of sessions per week. Further study of the effects of recreation periods during therapy work days or of more days scheduled without therapy will help clarify what conditions for delivering animal-assisted service best safeguard the welfare of dog and dog handler teams.

Androgen Serum Levels in Women with Premature Ovarian Failure Compared to Fertile and Menopausal Controls

OBJECTIVE The purpose of our study was to examine androgen serum levels and bone density in women with premature ovarian failure (POF) compared to healthy normal controls. STUDY DESIGN Thirty-three women 19-35 years of age with idiopathic POF were compared to 33 well-matched women with normal ovarian function and 32 healthy postmenopausal (PMP) women concerning 17-hydroxyprogesterone (17-OHP), androstendione (A), testosterone (T), dehydroepiandrosterone-sulfate (DHEAS), insulin-like growth factor 1 (IGF-1), as well as bone density (BD). RESULTS Women with POF showed statistically significantly lower concentrations of 17-OHP, A, T (p < 0.001) and a reduced bone density (p < 0.001) compared to fertile controls. No differences were found between POF and PMP women concerning estradiol (E2), T, A and 17-OHP. Regarding DHEAS, no statistically significant differences were found between women with POF and fertile controls whereas PMP women proved to have significantly lower DHEAS concentrations than fertile controls. Women with POF had the highest IGF-1 serum concentrations and PMP women the lowest. CONCLUSION An important decrement of ovarian steroids and bone density was noticed in women with POF, while the time since menopause had no influence on androgen concentrations. The hormone concentrations in women with POF are similar to those observed in normal PMP women with the exception of DHEAS and IGF-1 levels.

Gender Differences in Body Composition from Childhood to Old Age: An Evolutionary Point of View

Abstract In this cross-sectional study gender differences in body composition (relative fat mass and lean body mass adjusted by height) were analyzed among 869 girls and 780 boys aging between 6 and 18 years and 513 adult women and 412 adult men aging between 19 and 92 years. Body composition was determined by BIA method among children and adolescents and dual energy x-ray absorptiometry (DEXA) among adults. It could be shown that males and females differed significantly in body composition throughout life. Even during prepuberty, girls exhibited a significantly higher amount of body fat and a significantly lower amount of lean body mass than their male counterparts. These gender differences are found throughout life. The observed results are interpreted in a proximate and an ultimate sense. Furthermore the impact of modern life style in industrialized countries is discussed.