T. A. Armstrong

Effect of pharmacological concentrations of dietary copper on lipid and cholesterol metabolism in pigs

Abstract An experiment was conducted to determine if pharmacological concentrations of copper (Cu) affect lipid and cholesterol metabolism in Cu-adequate pigs. Treatments consisted of: control (10 ppm Cu as cupric sulfate, CuSO 4 ); control + 66 or 225 ppm Cu as CuSO 4; control + 33, 66, or 100 ppm Cu as cupric citrate (CuCit). Pigs were fed their respective diets throughout the nursery (35 d) and growing-finishing (GF; 103 d) phases. Copper increased (P 4 relative to the control on d 42 of the GF phase. Percent lipid and cholesterol concentrations of the semitendinosus muscle were not affected by Cu. Lipid percentage of the longissimus muscle was decreased (P 4 compared to the control, but Cu did not affect cholesterol concentration or fatty acid profile. These results indicate that pharmacological concentrations of Cu have little effect on cholesterol and lipid metabolism in the Cu-adequate pig.

EFFECT OF DIETARY COPPER LEVEL AND HIGH SULFATE WATER ON COPPER METABOLISM AND GROWTH IN CATTLE

High levels of supplemental inorganic Cu depress intake and increase hepatic Cu stores in the presence of high SO4 water. High SO4 water decreases liver and rumen soluble Cu concentrations.