T. D. Venu
University of Mysore
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Featured researches published by T. D. Venu.
Bioorganic & Medicinal Chemistry Letters | 2008
T. D. Venu; Shaukath Ara Khanum; Aiysha Firdouse; B.K. Manuprasad; S. Shashikanth; Riyaz Mohamed; Bannikuppe Sannanaik Vishwanth
Reaction of 6a-f individually with 2-methylsulfonyl-4,6-dimethoxypyrimidine yielded 7a-f in excellent yield. The newly synthesized heterocycles were characterized by IR, (1)H NMR, and mass spectral data. Compounds 7a-f was screened for their anti-inflammatory activity and were compared with standard drugs. Of the compounds studied, the compound 7e showed more potent activity than the standard drugs at all doses tested.
Chemical Biology & Drug Design | 2010
Neithnadka Premsai Rai; T. D. Venu; B.K. Manuprasad; S. Shashikanth; Pirama Nayagam Arunachalam; Aiysha Firdouse
A series of 2‐[2‐(aroyl‐aroxy)‐methyl]‐4‐phenyl‐1,3‐thiazoles 4a–j were obtained via multiple step synthesis sequence beginning with the hydroxybenzophenones (1a–g). Hydroxybenzophenones on reaction with chloroacetonitrile affords [(2‐benzoyl) phenoxy] acetonitrile (2a–g), which reacts with H2S/NH4OH and yields [(2‐benzoyl) phenoxy] acetothiamide (3a–g), which on treatment with phenacylbromides affords 2‐[2‐(aroyl‐aroxy)‐methyl]‐4‐phenyl‐1,3‐thiazoles (4a–j). All the newly synthesized compounds were evaluated for their anti‐inflammatory activity and were compared with standard drugs. Of the compounds studied, (4g), compounds with chloro substituents showed more potent activity than the standard drug phenyl butazone at all doses tested.
Molecular Crystals and Liquid Crystals | 2009
B. N. Lakshminarayana; J. Shashidhara Prasad; T. D. Venu; B.K. Manuprasad; M. A. Sridhar; S. Shashikanth
The title compound, (2-((6-chloropyridin-3-yl)methoxy)-5-methylphenyl)(p-tolyl) methanone, was synthesized and characterized spectroscopically and finally confirmed by (XRD) study. The title compound crystallizes in the monoclinic space group P21/c with cell parameters a = 9.4420(1) Å, b = 7.9810(6) Å, c = 23.777(4) Å, α = 90°, β = 90.883(3)°, γ = 90°, V = 1791.5(4) Å−3, and Z = 4. The structure exhibits intermolecular hydrogen bond of the type C‒H···O.
Acta Crystallographica Section E-structure Reports Online | 2006
S. Naveen; T. D. Venu; S. Shashikanth; M. A. Sridhar; J. Shashidhara Prasad
In the title compound, C22H17FO3, there are weak intermolecular C-H center dot center dot center dot O hydrogen bonds resulting in the formation of a polymeric chain.
Molecular Crystals and Liquid Crystals | 2009
S. Neetha; T. D. Venu; M. A. Sridhar; J. Shashidhara Prasad; S. Shashikanth
The title compound, C20H13Cl2NO4, crystallizes in the monoclinic crystal system and space group P21/n with cell parameters a = 9.434(2) Å, b = 13.167(3) Å, c = 15.087(4) Å, β = 105.289(8)°, V = 1807.7(7) Å3 for Z = 4. The structure exhibits inter-molecular hydrogen bonds of the type C-HċO.
Acta Crystallographica Section E-structure Reports Online | 2005
S. Naveen; T. D. Venu; S. Shashikanth; M. A. Sridhar; J. Shashidhara Prasad
In the title compound, C15H14ClO2, the dihedral angle between the two benzene rings is 57.37 (12)°.
Bioorganic & Medicinal Chemistry | 2007
T. D. Venu; S. Shashikanth; Shaukath Ara Khanum; S. Naveen; Aiysha Firdouse; M. A. Sridhar; J. Shashidhara Prasad
Journal of Chemical Crystallography | 2005
M. Mahendra; Beeranahally H. Doreswamy; M. A. Sridhar; J. Shashidhara Prasad; Shaukath Ara Khanum; S. Shashikanth; T. D. Venu
Acta Crystallographica Section E: Crystallographic Communications | 2004
L. Sieron; S. Shashikanth; H. S. Yathirajan; T. D. Venu; Basavegowda Nagaraj; Padmarajaiah Nagaraja; Shaukath Ara Khanum
Journal of Chemical Crystallography | 2007
S. Naveen; T. D. Venu; S. Shashikanth; M. A. Sridhar; J. Shashidhara Prasad