T. Kizaki

Muscle type-specific response of PGC-1α and oxidative enzymes during voluntary wheel running in mouse skeletal muscle

Aim:  It is generally accepted that endurance exercise increases the expression of peroxisome proliferator‐activated receptor γ coactivator‐1α (PGC‐1α), which governs the expression of oxidative metabolic enzymes. A previous report demonstrated that the regulation of mitochondrial protein expression in skeletal muscles in response to cold exposure depends on muscle fibre type. Cold exposure and endurance exercise are both metabolic challenges that require adjustments in mitochondrial energy metabolism, we hypothesized that the exercise‐induced increase in oxidative enzymes and PGC‐1α expression is higher in fast‐type than in slow‐type muscle.

Effects of exercise training on adipogenesis of stromal-vascular fraction cells in rat epididymal white adipose tissue: Effects of exercise training on adipogenesis

Aim:  Previous studies have shown that exercise training reduced white adipose tissue (WAT) mass compared to that in sedentary controls, and that the smaller mass contained fewer adipocytes. However, the effect of exercise training on adipogenesis is not completely clear. Therefore, we re‐examined the effect of exercise training on adipocyte numbers in WAT and, if such an effect was found tested the adipogenic responses of stromal‐vascular fraction (SVF) cells containing adipose tissue‐derived stem cells (ADSC) in epididymal WAT from exercise‐trained (TR) rats.

Intermittent hypobaric hypoxia increases the ability of neutrophils to generate superoxide anion in humans

1. We investigated the effect of intermittent exposure to hypobaric hypoxia on the ability of neutrophils to generate ·O2–.