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Archives of Biochemistry and Biophysics | 1954

Fatty acid and cholesterol synthesis rates in the intact rat.

T. T. Hutchens; J. T. Van Bruggen; Edward S. West

Abstract An approach to the determination of lipide synthesis rates in the individual intact rat using single tracer injection, short-term experiments is described. Use is made of respiratory C 14 O 2 data to evaluate the carbon flux through the precursor stages. Fatty acid and cholesterol synthesis rates determined in this manner are reported as mg. lipide synthesized/ hr./100 g. animal weight for total animal, liver, and carcass of normal, chow-fed Sprague-Dawley rats in the postprandial, postabsorptive, and 18-hr. fasted states.


Journal of Biological Chemistry | 1952

The effect of fasting upon lipogenesis in the intact rat.

J. T. Van Bruggen; T. T. Hutchens; C. K. Claycomb; W. J. Cathey; Edward S. West


Journal of Biological Chemistry | 1954

The effect of fasting upon tissue lipogenesis in the intact rat.

T. T. Hutchens; J. T. Van Bruggen; R. M. Cockburn; Edward S. West


Journal of Biological Chemistry | 1953

Time course of lipide labeling in the intact mouse and rat.

J. T. Van Bruggen; T. T. Hutchens; C. K. Claycomb; Edward S. West


Federation Proceedings. Federation of American Societies for Experimental Biology | 1951

METABOLISM OF CHOLESTEROL ABSORPTION, TISSUE DISTRIBUTION, AND FATTY ACID SYNTHESIS

J.T. Van Bruggen; T. T. Hutchens; Edward S. West


Archive | 1955

MEASUREMENT OF RESPIRATORY C¹⁴O ACTIVITIES

John van Bruggen; T. T. Hutchens


Archive | 1951

PREPARATION OF BIOSYNTHESIZED C¹⁴ LABELED CHOLESTEROL

John van Bruggen; T. T. Hutchens; Hartford Square West


Archive | 1951

PREPARATION OF BIOSYNTHESIZED C

J.T. Van Bruggen; T. T. Hutchens; H.S. West


Archive | 1951

sup 14

John van Bruggen; T. T. Hutchens; Edward S. West


Federation Proceedings. Federation of American Societies for Experimental Biology | 1951

LABELED CHOLESTEROL

T. T. Hutchens; J. T. Van Bruggen; C. K. Claycomb; W. J. Cathey

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Edward S. West

Washington University in St. Louis

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