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Tadasu Sakai

Vanderbilt University Medical Center

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Publication

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Journal of Japanese Society for Dialysis Therapy | 1992

Serial NCV changes with long-term CAPD.

Yutaka Takagi; Kazuo Kumano; Tadasu Sakai; Yuichiro Takahashi

CAPDは血液透析 (HD) に比べ中～大分子量物質除去特性に優れており, uremic neuropathyに対する優位性が推測される. 我々は長期CAPD治療におけるuremic neuropathyの動向を検討するため, 経時的にNCV (nerve conduction velocity) 測定を行った. また, 透析歴48-72か月におけるNCVを, CAPDとHD患者で比較した. CAPD患者のNCVは経時的にみるとわずかだが徐々に低下する傾向を認めた. 特に正中神経で変化が現れやすかった. しかし, HD患者ではCAPD患者よりSCVは低下しており, CAPDの方がHDより障害は軽微と考えられた. 小分子量物質の血中濃度, 除去能とNCVには相関はみられなかった. 以上よりCAPD療法においても, 長期的にはNCVは徐々に低下するものと考えられた.

Kidney International | 1991

Role for uremic toxin in the progressive loss of intact nephrons in chronic renal failure

Masaru Motojima; Fuyuhiko Nishijima; Masaaki Ikoma; Tetsuya Kawamura; Toshimasa Yoshioka; Agnes B. Fogo; Tadasu Sakai; Iekuni Ichikawa

Kitasato medicine | 1998

Changes of Peritoneal Net Fluid Absorption Rate (PNFAR) in Long Term Continuous Ambulatory Peritoneal Dialysis (CAPD) Patient

Hideshi Shiokawa; Kazuo Kumano; Tadasu Sakai

北里医学 | 1997

A Nephrotoxic Mechanism of FK506 is Partially Related to TGF-β Production in Cultured Renal Proximal Tubular Cells in vitro

Ping Ma; Kazuo Kumano; Toru Hyodo; Shinji Yokota; Tadasu Sakai

Journal of Japanese Society for Dialysis Therapy | 1993

Removal and replacement of peritoneal catheter in a single operation for resistant peritonitis in CAPD patients.

Kazuo Kumano; Satoshi Shimura; Shinji Yokota; Tadasu Sakai; Midori Hojyo; Kikuo Iitaka

Journal of Japanese Society for Dialysis Therapy | 1993

Pharmacokinetics of Isepamicin Sulfate in patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis.

Mikitoshi Go; Kazuo Kumano; Tadasu Sakai; Masakazu Kuroyama; Toshimi Kimura; Fumiya Tomonaga

Journal of Japanese Society for Dialysis Therapy | 1993

Protein binding of calcitriol in patients with chronic renal failure.

Masakazu Kuroyama; Fumiya Tomonaga; Kazuo Kumano; Tadasu Sakai; Sachiko Nakayama; Hideo Fukazawa

Journal of Japanese Society for Dialysis Therapy | 1993

Peritoneal permeability and lymphatic absorption in CAPD patients.

Kazuo Kumano; Satoshi Shimura; Yutaka Takagi; Shinji Yokota; Tadasu Sakai

Journal of Japanese Society for Dialysis Therapy | 1993

Changes in protein binding of various cephems during and after hemodialysis. Effects of anticoagulants.

Masakazu Kuroyama; Kazuo Kumano; Setsuko Murase; Fumiya Tomonaga; Tadasu Sakai

Journal of Japanese Society for Dialysis Therapy | 1991

Protein binding of cefpiramide in healthy subjects and patients with chronic renal failure.

Masakazu Kuroyama; Kazuo Kumano; Setsuko Murase; Fumiya Tomonaga; Tadasu Sakai

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Kazuo Kumano

Kitasato University

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Kikuo Iitaka

Kitasato University

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Fumiya Tomonaga

Kitasato University

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Masakazu Kuroyama

Kitasato University

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Noriaki Kasai

Kitasato University

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Toshimasa Yoshioka

Vanderbilt University Medical Center

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Shinji Yokota

Kitasato University

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Yutaka Takagi

Kitasato University

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Midori Hojo

Kitasato University

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Setsuko Murase

Kitasato University

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