Taijiro Mukai

Tiapride for pathological jealousy (Othello syndrome) in elderly patients

Pathological jealousy can be seen in all generations. It is known to be difficult to treat, especially in older patients. In middle‐aged patients, it is commonly treated with neuroleptics like pimozide but in elder patients treatment options are limited because of the adverse side‐effects of neuroleptics, such as extrapyramidal syndrome. The present study documents the successful treatment of a 98‐year‐old Japanese man who showed pathological jealousy using tiapride without any adverse side‐effects. Concluding that tiapride might be considered the medicine of choice in all kinds of monodelusional disorders among the elderly.

Tiapride for monosymptomatic hypochondriacal psychosis (dysmorphic delusion subtype) in presenile patients

Monosymptomatic hypochondriacal psychosis (dysmorphic delusion subtype) can be seen in people of all ages. It is well known as being difficult to treat, especially in presenile and older patients. In younger patients, it is commonly treated with neuroleptics like pimozide but in presenile and older patients this form of treatment is limited because of the aversive side‐effects of neuroleptics, such as extrapyramidal syndrome. The present study describes a successful course of treatment with tiapride in a presenile patient with monosymptomatic hypochondoriacal psychosis (dysmorphic delusion subtype) without any adverse side‐effects when compared to other treatments and monodelusional disorders in elderly people. It is concluded that tiapride should be considered the treatment of choice for monodelusional disorders in presenile people.