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Takafumi Fujioka

Otsuka Pharmaceutical

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Publication

Featured researches published by Takafumi Fujioka.

Bioorganic & Medicinal Chemistry Letters | 2002

A practical synthesis of 3,4-diethoxybenzthioamide based on Friedel-Crafts reaction with potassium thiocyanate in methanesulfonic acid.

Shinji Aki; Takafumi Fujioka; Masashi Ishigami; Jun-ichi Minamikawa

The synthesis of 3,4-diethoxybenzthioamide, the key intermediate for OPC-6535, is achieved by employing Friedel-Crafts reaction of 1,2-diethoxybenzene with potassium thiocyanate in methanesulfonic acid at ambient temperature.

Journal of Medicinal Chemistry | 1992

Novel positive inotropic agents : synthesis and biological activities of 6-(3-amino-2-hydroxypropoxy)-2(1H)-quinolinone derivatives

Takafumi Fujioka; Shuji Teramoto; Toyoki Mori; Tetsumi Hosokawa; Takumi Sumida; Michiaki Tominaga; Youichi Yabuuchi

Archive | 1991

Carbostyril derivatives and pharmaceutical composition containing the same

Kazuo Banno; Takafumi Fujioka; Masaaki Osaki; Kazuyuki Nakagawa

Archive | 1985

CARBOSTYRIL COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME

Michiaki Tominaga; Takafumi Fujioka; Kazuyoshi Nagami; Kazuyuki Nakagawa

Archive | 1994

Peripheral vasodilating agent containing piperidine derivative as active ingredient

Takafumi Fujioka; Shuji Teramoto; Michinori Tanaka; Hiroshi Shimizu; Fujio Tabusa; Michiaki Tominaga

Chemical & Pharmaceutical Bulletin | 1988

Studies on 2(1H)-quinolinone derivatives as neuroleptic agents. I: Synthesis and biological activities of (4-phenyl-1-piperazinyl)-propoxy-2(1H)-quinolinone derivatives

Kazuo Banno; Takafumi Fujioka; Tetsuro Kikuchi; Yasuo Oshiro; Takashi Hiyama; Kazuyuki Nakagawa

Archive | 1986

Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same

Atsushi Abiko; Takafumi Fujioka; Kazuyuki Nakagawa; Kazumi Kondo

Archive | 1994

Agent for treating thrombosis and phosphodiesterase inhibitor

Takafumi Fujioka; Shuji Teramoto; Michiaki Tominaga; Yoichi Yabuuchi

Archive | 1994

Peripheral vasodilating agent containing n-acylated 4-amino piperidine derivatives as active ingredients

Takafumi Fujioka; Shuji Teramoto; Michinori Tanaka; Hiroshi Shimizu; Fujio Tabusa; Michiaki Tominaga

Archive | 1991

Carbostyril derivatives and salts thereof

Shigeharu Tamada; Takafumi Fujioka; Hidenori Ogawa; Shuji Teramoto; Kazumi Kondo

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Michiaki Tominaga

Otsuka Pharmaceutical

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Shuji Teramoto

Otsuka Pharmaceutical

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Kazuyuki Nakagawa

Otsuka Pharmaceutical

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Kazuo Banno

Otsuka Pharmaceutical

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Yoichi Yabuuchi

Otsuka Pharmaceutical

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Hidenori Ogawa

Otsuka Pharmaceutical

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Yasuo Oshiro

Otsuka Pharmaceutical

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Kazumi Kondo

Otsuka Pharmaceutical

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Michinori Tanaka

Otsuka Pharmaceutical

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Hiroshi Shimizu

Otsuka Pharmaceutical

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