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Publication
Featured researches published by Takafumi Kohama.
Microbiology and Immunology | 1994
Takafumi Kohama; Toshiaki Katayama; Masatoshi Inukai; Hiroaki Maeda; Akio Shiraishi
We tested the in vivo activity of leustroducsin B (LSN B), a new colony‐stimulating factor (CSF) inducer isolated from the culture broth of Streptomyces platensis, with mice infected with Escherichia coli. Treatment with LSN B augmented the host resistance to lethal infection of E. coli at doses between 0.1 mg/kg and 1 mg/kg. Serum interleukin‐6 (IL‐6) levels were found to increase after this treatment, and superoxide anion generation of neutrophils was enhanced in vivo, suggesting that LSN B augmented the host resistance at least in part by inducing IL‐6, which subsequently enhanced the bactericidal activity of the neutrophils.
The Journal of Antibiotics | 1993
Takafumi Kohama; Takemichi Nakamura; Takeshi Kinoshita; Isao Kaneko; Akio Shiraishi
The Journal of Antibiotics | 1993
Takafumi Kohama; Ryuzo Enokita; Takao Okazaki; Hiroko Miyaoka; Akio Torikata; Masatoshi Inukai; Isao Kaneko; Takeshi Kagasaki; Yoshiharu Sakaida; Akira Satoh; Akio Shiraishi
The Journal of Antibiotics | 1996
Takafumi Kohama; Hiroaki Maeda; Junko Imada Sakai; Akio Shiraishi; Kazuo Yamashita
The Journal of Antibiotics | 1995
Tomoyuki Shibata; Shinwa Kurihara; Tetsuo Oikawa; Nobuyuki Ohkawa; Naomi Shimazaki; Kazuhiko Sasagawa; Tomowo Kobayashi; Takafumi Kohama; Fumitoshi Asai; Akio Shiraishi; Yukio Sugimura
Archive | 1992
Takafumi Kohama; Isao Kaneko; Takemichi Nakamura; Takeshi Kagasaki; Ryuzo Enokita; Keiichi Matsuda
The Journal of Antibiotics | 1993
Takafumi Kohama; Hiroko Miyaoka; Akio Torikata; Masatoshi Inukai; Isao Kaneko; Akio Shiraishi
Archive | 2000
Takafumi Kohama; Isao Kaneko; Takemichi Nakamura
Archive | 1994
Yukio Sugimura; Tomoyuki Shibata; Kazuhiko Tamaki; Shinwa Kurihara; Takafumi Kohama; Akio Shiraishi; Tomowo Kobayashi; Kazuhiko Sasagawa; Naomi Shimazaki
Archive | 1994
Takafumi Kohama; Isao Kaneko; Takemichi Nakamura; Takeshi Kagasaki; Ryuzo Enokita; Keiichi Matsuda
Collaboration
Dive into the Takafumi Kohama's collaboration.
