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Takafumi Mukaihira

Mochida Pharmaceutical Co., Ltd

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Publication

Featured researches published by Takafumi Mukaihira.

Archive | 1998

Aromatic compounds having cyclic amino or salts thereof

Hidemitsu Nishida; Yoshitaka Hosaka; Yutaka Miyazaki; Tomokazu Matsusue; Takafumi Mukaihira

Chemical & Pharmaceutical Bulletin | 2002

Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as a Factor Xa Inhibitor II. Substituent Effect on Biological Activities

Hidemitsu Nishida; Yutaka Miyazaki; Takafumi Mukaihira; Fumihiko Saitoh; Miyuki Fukui; Kousuke Harada; Manabu Itoh; Aki Muraoka; Tomokazu Matsusue; Atsushi Okamoto; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi; Hidenori Mochizuki

Archive | 1997

Nerve cell protective agents

Ichiro Yamamoto; Manabu Itoh; Masato Shimojo; Yasunobu Yumiya; Takafumi Mukaihira; Yasushige Akada

Chemical & Pharmaceutical Bulletin | 2004

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors IV. A series of new derivatives containing a spiro[5H-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidin]-5-one skeleton.

Fumihiko Saitoh; Takafumi Mukaihira; Hidemitsu Nishida; Tsutomu Satoh; Akihiro Okano; Yasunobu Yumiya; Munetaka Ohkouchi; Rumi Johka; Tomokazu Matsusue; Ikuya Shiromizu; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi

Chemical & Pharmaceutical Bulletin | 2004

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.

Hidemitsu Nishida; Yutaka Miyazaki; Takafumi Mukaihira; Hiroyasu Shimada; Kazuhiro Suzuki; Fumihiko Saitoh; Masashi Mizuno; Tomokazu Matsusue; Atsushi Okamoto; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi; Hidenori Mochizuki

Archive | 2000

Tricyclic compounds having spiro union

Hidemitsu Nishida; Fumihiko Saitoh; Kousuke Harada; Ikuya Shiromizu; Takafumi Mukaihira

Chemical & Pharmaceutical Bulletin | 2007

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors(1-6) VI. A series of new derivatives containing N,S- and N,SO2-spiro acetal scaffolds.

Fumihiko Saitoh; Hidemitsu Nishida; Takafumi Mukaihira; Naoto Kosuga; Munetaka Ohkouchi; Tomokazu Matsusue; Ikuya Shiromizu; Yoshitaka Hosaka; Miwa Matsumoto; Ichiro Yamamoto

Archive | 2001

Cholesterol biosynthesis inhibitors containing as the active ingredient tricyclic spiro compounds

Hidemitsu Nishida; Takafumi Mukaihira

European Journal of Organic Chemistry | 2006

Asymmetric Synthesis of Antithrombotic Agent M55529: The First Enantioselective Cyclic N,O-Acetal Formation

Fumihiko Saitoh; Hidemitsu Nishida; Takafumi Mukaihira; Kohsuke Aikawa; Koichi Mikami

European Journal of Organic Chemistry | 2006

Asymmetric Synthesis of Antithrombotic Agents M58163 and M58169: Dynamic Kinetic Resolution in Amide Formation Catalyzed by La‐Linked BINOL Complex

Fumihiko Saitoh; Hidemitsu Nishida; Takafumi Mukaihira; Kohsuke Aikawa; Koichi Mikami

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Collaboration

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Hidemitsu Nishida

Mochida Pharmaceutical Co.

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Fumihiko Saitoh

Mochida Pharmaceutical Co.

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Tomokazu Matsusue

Mochida Pharmaceutical Co.

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Yoshitaka Hosaka

Mochida Pharmaceutical Co.

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Miwa Matsumoto

Mochida Pharmaceutical Co.

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Yutaka Miyazaki

Mochida Pharmaceutical Co.

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Ikuya Shiromizu

Mochida Pharmaceutical Co.

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Kohsuke Aikawa

Tokyo Institute of Technology

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Koichi Mikami

Tokyo Institute of Technology

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Manabu Itoh

Mochida Pharmaceutical Co.

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