Takafumi Mukaihira | Researchain

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Featured researches published by Takafumi Mukaihira.

Archive | 1998

Aromatic compounds having cyclic amino or salts thereof

Hidemitsu Nishida; Yoshitaka Hosaka; Yutaka Miyazaki; Tomokazu Matsusue; Takafumi Mukaihira

Chemical & Pharmaceutical Bulletin | 2002

Synthesis and Evaluation of 1-Arylsulfonyl-3-piperazinone Derivatives as a Factor Xa Inhibitor II. Substituent Effect on Biological Activities

Hidemitsu Nishida; Yutaka Miyazaki; Takafumi Mukaihira; Fumihiko Saitoh; Miyuki Fukui; Kousuke Harada; Manabu Itoh; Aki Muraoka; Tomokazu Matsusue; Atsushi Okamoto; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi; Hidenori Mochizuki

Archive | 1997

Nerve cell protective agents

Ichiro Yamamoto; Manabu Itoh; Masato Shimojo; Yasunobu Yumiya; Takafumi Mukaihira; Yasushige Akada

Chemical & Pharmaceutical Bulletin | 2004

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors IV. A series of new derivatives containing a spiro[5H-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidin]-5-one skeleton.

Fumihiko Saitoh; Takafumi Mukaihira; Hidemitsu Nishida; Tsutomu Satoh; Akihiro Okano; Yasunobu Yumiya; Munetaka Ohkouchi; Rumi Johka; Tomokazu Matsusue; Ikuya Shiromizu; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi

Chemical & Pharmaceutical Bulletin | 2004

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.

Hidemitsu Nishida; Yutaka Miyazaki; Takafumi Mukaihira; Hiroyasu Shimada; Kazuhiro Suzuki; Fumihiko Saitoh; Masashi Mizuno; Tomokazu Matsusue; Atsushi Okamoto; Yoshitaka Hosaka; Miwa Matsumoto; Shuhei Ohnishi; Hidenori Mochizuki

Archive | 2000

Tricyclic compounds having spiro union

Hidemitsu Nishida; Fumihiko Saitoh; Kousuke Harada; Ikuya Shiromizu; Takafumi Mukaihira

Chemical & Pharmaceutical Bulletin | 2007

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors(1-6) VI. A series of new derivatives containing N,S- and N,SO2-spiro acetal scaffolds.

Fumihiko Saitoh; Hidemitsu Nishida; Takafumi Mukaihira; Naoto Kosuga; Munetaka Ohkouchi; Tomokazu Matsusue; Ikuya Shiromizu; Yoshitaka Hosaka; Miwa Matsumoto; Ichiro Yamamoto

Archive | 2001