Takaharu Tsutsumi
Teijin
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Publication
Featured researches published by Takaharu Tsutsumi.
Bioorganic & Medicinal Chemistry Letters | 2008
Wilna J. Moree; Kenichiro Kataoka; Michele M. Ramirez-Weinhouse; Tatsuki Shiota; Minoru Imai; Takaharu Tsutsumi; Masaki Sudo; Noriaki Endo; Yumiko Muroga; Takahiko Hada; Dewey Fanning; John Saunders; Yoshinori Kato; Peter L. Myers; Christine M. Tarby
SAR studies were conducted around lead compound 1 using high-throughput parallel solution and solid phase synthesis. Our lead optimization efforts led to the identification of several CCR2b antagonists with potent activity in both binding and functional assays [Compound 71 CCR2b Binding IC(50) 3.2 nM; MCP-1-Induced Chemotaxis IC(50) 0.83 nM; Ca(2+) Flux IC(50) 7.5 nM].
Archive | 1998
Tatsuki Shiota; Kenichiro Kataoka; Minoru Imai; Takaharu Tsutsumi; Masaki Sudoh; Ryo Sogawa; Takuya Morita; Takahiko Hada; Yumiko Muroga; Osami Takenouchi; Monoru Furuya; Noriaki Endo; Christine M. Tarby; Wilna Moree; Steven L. Teig
Bioorganic & Medicinal Chemistry Letters | 2004
Wilna J. Moree; Kenichiro Kataoka; Michele M. Ramirez-Weinhouse; Tatsuki Shiota; Minoru Imai; Masaki Sudo; Takaharu Tsutsumi; Noriaki Endo; Yumiko Muroga; Takahiko Hada; Hiroko Tanaka; Takuya Morita; Jonathan Greene; Doug Barnum; John Saunders; Yoshinori Kato; Peter L. Myers; Christine M. Tarby
Bioorganic & Medicinal Chemistry Letters | 2004
Minoru Imai; Tatsuki Shiota; Kenichiro Kataoka; Christine M. Tarby; Wilna J. Moree; Takaharu Tsutsumi; Masaki Sudo; Michele M. Ramirez-Weinhouse; Daniel D. Comer; Chung-Ming Sun; Shinsuke Yamagami; Hiroko Tanaka; Takuya Morita; Takahiko Hada; Jonathan Greene; Doug Barnum; John Saunders; Peter L. Myers; Yoshinori Kato; Noriaki Endo
Archive | 1996
Kenichiro Kataoka; Toru Minoshima; Tatsuki Shiota; Takaharu Tsutsumi; Takahiko Hada; Hiroko Tanaka; Takuya Morita; Noriaki Endo
Archive | 2004
Takaharu Tsutsumi; Satoshi Sugiura; Masahiro Koga; Yoshiyuki Matsumoto; Toshihiro Ishii; Akira Nakano; Gen Unoki; Yuri Sakai; Reiko Takarada; Hiroko Ogawa
Archive | 2003
Kenichiro Kataoka; Tomomi Kosugi; Toshihiro Ishii; Takahiro Takeuchi; Takaharu Tsutsumi; Akira Nakano; Gen Unoki; Masanori Yamamoto; Yuri Sakai
Archive | 1996
Kenichiro Kataoka; Toru Minoshima; Tatsuki Shiota; Takaharu Tsutsumi; Takahiko Hada; Hiroko Tanaka; Takuya Morita; Noriaki Endo
Archive | 2004
Takaharu Tsutsumi; Satoshi Sugiura; Masahiro Koga; Yoshiyuki Matsumoto; Toshihiro Ishii; Akira Nakano; Gen Unoki; Yuri Sakai; Reiko Takarada; Hiroko Ogawa
Archive | 2000
Satoshi Sugiura; Takaharu Tsutsumi; Yorimasa Suwa; Takami Arai; Katsutoshi Sakurai; Noboru Yoshioka; Akira Tanokura; Jun Suzuki
