Takashi Yao

Primary gastrointestinal lymphoma in Japan: a clinicopathologic analysis of 455 patients with special reference to its time trends.

An optimal treatment modality for patients with primary gastrointestinal lymphoma has not yet been established. This study aimed to elucidate the clinicopathologic features of this disease and the influence of therapeutic modalities on the prognosis in Japanese patients

Helicobacter pylori and primary gastric lymphoma

Few previous articles have analyzed the relation between infection with Helicobacter pylori (H. pylori) and primary gastric lymphoma in a large number of patients.

Primary gastric lymphoma. A clinicopathologic study of 233 cases with special reference to evaluation with the MIB-1 index

Background. Few articles have analyzed the prognostic data from a large series of primary gastric lymphoma classified according to the concept of mucosa‐associated lymphoid tissue (MALT).

Cancer in peutz‐jeghers syndrome

Background. Peutz‐Jeghers (P‐J) syndrome has been found to be associated with an increased risk of malignant neoplasia.

Long‐term clinical outcome of Helicobacter pylori eradication for gastric mucosa‐associated lymphoid tissue lymphoma with a reference to second‐line treatment

The goals of the current study were to elucidate the long‐term outcome of Helicobacter pylori eradication therapy for gastric mucosa‐associated lymphoid tissue (MALT) lymphoma and to clarify the therapeutic efficacy of stomach‐conserving treatments for patients not responding to eradication therapy.

A clinicopathologic study of primary small intestine lymphoma

It remains unclear whether the presence of mucosa‐associated lymphoid tissue (MALT) lymphoma has prognostic implications for patients with primary small intestine lymphoma.

Synchronous and metachronous primary gastric lymphoma and adenocarcinoma

The occurrence of both malignant gastric lymphoma and adenocarcinoma in the same patient is very rare.

A clinicopathologic study of small flat colorectal carcinoma.

Background. Recent studies have noted that small flat carcinomas do exist in the human colon, but their clinicopathologic features have not been fully delineated.

Long-term follow-up study of patients with gastric adenomas with malignant transformation. An immunohistochemical and histochemical analysis.

Background. Little is known about the changes in the immunohistochemical and histochemical characteristics that take place during the malignant transformation of gastric adenoma (GA).

Minute gastric carcinoma of differentiated type with special reference to the significance of intestinal metaplasia, proliferative zone, and p53 protein during tumor development

The differentiated type of minute gastric carcinoma (MGC), measuring less than 5 mm in greatest dimension, has been considered to represent the incipient phase of gastric carcinoma. To determine the clinicopathologic features of MGCs, the authors examined tissues from MGCs with a view to clarifying their histopathologic diversity. The immunohistochemistry of these tissues was determined using monoclonal antibody against p53 and Ki‐67, and their mucin‐histochemical types were determined with reference to the presence of intestinal metaplasia (IM) within their surrounding mucosa.