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Dive into the research topics where Takashi Yusa is active.

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Featured researches published by Takashi Yusa.


Prostaglandins | 1980

The bronchodilator activity of 20-isopropylidene prostaglandin E2 (CS-412).

Takeshi Yamaguchi; Kiyoshi Sakai; Takashi Yusa; Mitsuo Yamazaki

The bronchodilator activity of 20-isopropylidene prostaglandin E2 (CS-412) was studied in vivo. In the conscious guinea pig, aerosols of CS-412, prostaglandin E2 (PGE2), or salbutamol afforded similar protection against histamine-induced convulsions. In the anesthetized guinea pig, where increase in intratracheal pressure was taken as an index of bronchoconstriction, CS-412, PGE2, and salbutamol were equipotent in inhibiting the broncho-constriction induced by histamine. CS-412, PGE2 and salbutamol were equally effective in reducing the serotonin-induced increase in pulmonary resistance in the anesthetized cat. CS-412 was different from PGE2 in bronchoconstrictor activity in anesthetized cats with normal bronchotonus. PGE2 caused bronchoconstriction in the cats. CS-412 showed 30 times less constrictor activity than PGE2. It was concluded that CS-412 is an effective bronchodilator without unfavorable side effects.


Archive | 1975

9ξ,15ξ-Dihydroxy-11α-hydroxymethylprost-13(trans)-enoic acid derivatives

Osamu Oda; Kiyoshi Sakai; Takashi Yusa; Hamako Katano


Archive | 1974

16,16-Dimethyl 9-oxo-11α-hydroxymethyl-15ε-hydroxyprosta-5(cis), 13(trans)-dienoic acid derivatives and process for the preparation thereof

Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa


Archive | 1975

9-Oxo-11α-methyl-15Ε-hyroxyprost-13(trans)-enoic acid derivatives and process for the preparaion thereof

Kiyoshi Sakai; Takashi Yusa; Junya Ide; Mitsuo Yamazaki; Shinsaku Kobayashi


Archive | 1972

CYCLOPENTANOL DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

Kiyoshi Sakai; Hamako Katano; Koichi Kojima; Takashi Yusa


Poultry Science | 1971

Residues of Beclotiamine, a New Coccidiostat, in Chicken Tissues and Egg Yolks, and its Toxicity to Chickens

Mitsuo Yamazaki; Masaaki Sasaki; Toshiaki Matsuzawa; Katsuro Kawada; Takashi Yusa


Archive | 1974

Prostanoic acid derivatives

Mitsuo Yamazaki; Masaaki Sasaki; Takashi Yusa; Kiyoshi Sakai; Osamu Oda; Kazuhiko Sasagawa


Archive | 1974

9-oxo-11alpha-hydroxymethyl-15xihydroxyprosta-5cis,13trans-diensaeure-derivate und verfahren zu ihrer herstellung 9-oxo-11alpha-hydroxymethyl-15xihydroxyprosta-5cis, 13trans-diensaeure derivatives and process for their production

Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa


Archive | 1974

9-oxo-11alpha-hydroxymethyl-15xihydroxyprosta-5cis, 13trans-diensaeure acid derivatives and process for their preparation

Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa


Archive | 1973

9-oxo-11 alpha-hydroxymethyl-15 xihydroxyprost-13(trans)-en-saeure-derivate und verfahren zu ihrer herstellung 9-oxo-11 alpha-hydroxymethyl-15 xihydroxyprost-13 (trans) -en-acid derivatives and process for their preparation

Osamu Oda; Kiyoshi Sakai; Takashi Yusa; Hamako Katano

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