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Publication
Featured researches published by Takashi Yusa.
Prostaglandins | 1980
Takeshi Yamaguchi; Kiyoshi Sakai; Takashi Yusa; Mitsuo Yamazaki
The bronchodilator activity of 20-isopropylidene prostaglandin E2 (CS-412) was studied in vivo. In the conscious guinea pig, aerosols of CS-412, prostaglandin E2 (PGE2), or salbutamol afforded similar protection against histamine-induced convulsions. In the anesthetized guinea pig, where increase in intratracheal pressure was taken as an index of bronchoconstriction, CS-412, PGE2, and salbutamol were equipotent in inhibiting the broncho-constriction induced by histamine. CS-412, PGE2 and salbutamol were equally effective in reducing the serotonin-induced increase in pulmonary resistance in the anesthetized cat. CS-412 was different from PGE2 in bronchoconstrictor activity in anesthetized cats with normal bronchotonus. PGE2 caused bronchoconstriction in the cats. CS-412 showed 30 times less constrictor activity than PGE2. It was concluded that CS-412 is an effective bronchodilator without unfavorable side effects.
Archive | 1975
Osamu Oda; Kiyoshi Sakai; Takashi Yusa; Hamako Katano
Archive | 1974
Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa
Archive | 1975
Kiyoshi Sakai; Takashi Yusa; Junya Ide; Mitsuo Yamazaki; Shinsaku Kobayashi
Archive | 1972
Kiyoshi Sakai; Hamako Katano; Koichi Kojima; Takashi Yusa
Poultry Science | 1971
Mitsuo Yamazaki; Masaaki Sasaki; Toshiaki Matsuzawa; Katsuro Kawada; Takashi Yusa
Archive | 1974
Mitsuo Yamazaki; Masaaki Sasaki; Takashi Yusa; Kiyoshi Sakai; Osamu Oda; Kazuhiko Sasagawa
Archive | 1974
Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa
Archive | 1974
Kiyoshi Sakai; Osamu Oda; Takashi Yusa; Mitsuo Yamazaki; Masaaki Sasaki; Kazuhiko Sasagawa
Archive | 1973
Osamu Oda; Kiyoshi Sakai; Takashi Yusa; Hamako Katano