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Prostaglandins | 1985

Central noradrenergic neurons and the hypertensive effects of intracerebroventricularly administered prostaglandin E2 in anaesthetized rabbits

Takeshi Otorii; Kazuhiro Ohkubo; Kenichi Suzuki

The participation of central noradrenergic neurons in the pressor responses to intracerebroventricular (i.c.v.) administration of prostaglandin (PG) E2 was studied in anaesthetized rabbits. The hypertensive effect induced by i.c.v. injection of PGE2 was inhibited by i.c.v. pretreatment with 6-hydroxydopamine and phentolamine, but not propranolol. These findings suggest that the cerebral noradrenergic neurons may be involved in the development of hypertensive effect of PGE2 through the adrenergic alpha-receptors.


Japanese Journal of Pharmacology | 1978

On the histamine receptor of the canine myocardium and coronary vasculature.

Keisuke Takeda; Yumi Katano; Yoshito Nakagawa; Tokumasa Tsukada; Toyozo Hashimoto; Mikio Nakazawa; Keitaro Hashimoto; Takeshi Otorii; Shoichi Imai


Japanese Journal of Pharmacology | 1977

EFFECTS OF CATECHOLAMINES ON THE MYOCARDIAL REDOX POTENTIAL

Takeshi Otorii; Keisuke Takeda; Yumi Katano; Yoshito Nakagawa; Shoichi Imai


Japanese Journal of Pharmacology | 1977

EFFECTS OF AMINOPHYLLINE, PROXYPHYLLINE AND A PROXYPHYLLINE-MELILOTUS EXTRACT-RUTIN MIXTURE (THEOESBERIVEN) ON THE HEART AND THE CORONARY CIRCULATION

Keisuke Takeda; Yumi Katano; Yoshito Nakagawa; Tokumasa Tsukada; Mikio Nakazawa; Takeshi Otorii; Shoichi Imai


Japanese Heart Journal | 1980

Effects of piridoxilate, a glyoxylic acid derivative, on the energy metabolism of the heart.

Takeshi Otorii; Yumi Katano; Keisuke Takeda; Shoichi Imai


Japanese Heart Journal | 1985

Antagonism of Hypotensive and Bradycardic Effects of Centrally Administered Guanfacine by Metiamide in Anesthetized Rabbits

Takeshi Otorii; Kazuhiro Ohkubo; Kenichi Suzuki


Japanese Heart Journal | 1984

Effects of cardioplegia induced by a young's solution (YNG solution) on the blood-perfused canine papillary muscle preparation.

Hiroshi Satoh; Kazuhiro Ohkubo; Kenichi Suzuki; Yumi Katano; Takeshi Otorii; Tomie Kawada; Seiichiro Yoshida; Shoichi Imai


Abstracts#R##N#Proceedings of the Seventh International Congress of Pharmacology | 1978

24 – ALTERATIONS IN MYOCARDIAL ENERGY METABOLISM DURING STIMULATION OF THE CARDIAC NERVES

T. Tsukada; Takeshi Otorii; Y. Nakagawa


Japanese Journal of Pharmacology | 1974

Proceedings: Modifications by pacing of the effects of catecholamines on the cardiac function and coronary circulation.

Shoichi Imai; Takeshi Otorii; Keisuke Takeda; Yumi Katano; Yoshito Nakagawa


Japanese Journal of Pharmacology | 1974

Proceedings: Effects of catecholamines on the canine myocardial redox potential.

Takeshi Otorii; Keisuke Takeda; Yumi Katano; Yoshito Nakagawa; Issei Matsubara

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