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Takuo Kosuge

University of Tokyo

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Agricultural and biological chemistry | 1971

Studies on Flavor Components of Foodstuffs:Part I Distribution of Tetramethylpyrazine in Fermented Foodstuffs

Takuo Kosuge; Hiroshi Zenda; Kunio Tsuji; Takeshi Yamamoto; Hiroko Narita

Distribution of tetramethylpyrazine (T.M.P.) in Japanese fermented foodstuffs was investigated by more accurate analytical method.Namely, the method was successful when trapping T.M.P. with picric acid after flash evaporation of the foodstuffs, followed by analysis with gas chromatography.T.M.P. was detected in many Japanese fermented foodstuffs, especially in Miso, Soy sause and Natto, which suggests that alkylpyrazines may play an important role as flavor of those foodstuffs.

Chemical & Pharmaceutical Bulletin | 1978

Isolation and Structure Studies of Mutagenic Principles in Amino Acid Pyrolysates

Takuo Kosuge; Kuniro Tsuji; Keiji Wakabayashi; Toshihiko Okamoto; Koichi Shudo; Yoichi Iitaka; Akiko Itai; Takashi Sugimura; Takashi Kawachi; Minako Nagao; Takie Yahagi; Yuko Seino

Nature | 1962

Discovery of a Pyrazine in a Natural Product : Tetramethylpyrazine from Cultures of a Strain of Bacillus subtilis

Takuo Kosuge; Hiroko Kamiya

Chemical & Pharmaceutical Bulletin | 1981

Identification of a reactive metabolite of the mutagen, 2-amino-3-methylimidazolo(4,5-f)quinoline.

Toshihiko Okamoto; Koichi Shudo; Yuichi Hashimoto; Takuo Kosuge; Takashi Sugimura; Susumu Nishimura

Chemical & Pharmaceutical Bulletin | 1976

Studies on cardiac principle of aconite root.

Takuo Kosuge; Masami Yokota

Chemical & Pharmaceutical Bulletin | 1977

Synthesis of a Mutagenic Principle isolated from Tryptophan Pyrolysate

Kei Takeda; Toshiharu Ohta; Koichi Shudo; Toshihiko Okamoto; Kuniro Tsuji; Takuo Kosuge

Chemico-Biological Interactions | 1978

Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.

Yuichi Hashimoto; Kei Takeda; Koichi Shudo; Toshihiko Okamoto; Takashi Sugimura; Takuo Kosuge

Chemical & Pharmaceutical Bulletin | 1981

A Potent Mutagen isolated from a Pyrolysate of L-Ornithine

Masami Yokota; Kusuo Narita; Takuo Kosuge; Keiji Wakabayashi; Minako Nagao; Takashi Sugimura; Kentaro Yamaguchi; Koichi Shudo; Yoichi Iitaka; Toshihiko Okamoto

Chemical & Pharmaceutical Bulletin | 1960

Entstehung von 3-Hydroxyderivaten bei der N-Oxydierung der Chinolinderivate mittels Wasserstoffperoxyds in Eisessig-Losung.

Eiji Ochiai; Chikara Kaneko; Iwao Shimada; Yumiko Murata; Takuo Kosuge; Shuichi Miyashita; Chikushi Kawasaki

Agricultural and biological chemistry | 1971

Studies on Flavor Components of Foodstuffs

Takuo Kosuge; Hiroshi Zenda; Kunio Tsuji; Takeshi Yamamoto; Hiroko Narita

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Koichi Shudo

University of Tokyo

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Masami Yokota

University of Shizuoka

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Toshihiko Okamoto

University of Tokyo

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Hiroshi Zenda

University of Tokyo

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Hiroyuki Sawanishi

Hokuriku University

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Takashi Sugimura

University of Tokyo

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Kei Takeda

University of Tokyo

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Keiji Wakabayashi

University of Tokyo

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Kuniro Tsuji

University of Tokyo

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Minako Nagao

University of Tokyo

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