Takuya Emoto

CT findings of leukemic pulmonary infiltration with pathologic correlation

The aim of this study was to demonstrate the characteristic CT findings of leukemic pulmonary infiltration based on the pathologic findings. The CT findings of 11 leukemic patients with leukemic pulmonary infiltration were compared with those of 22 leukemic patients with other diseases as a control group. Evaluated pulmonary parenchymal CT findings included thickening of bronchovascular bundles and interlobular septa, prominence of peripheral pulmonary arteries, ground-glass opacities, air-space consolidation, and nodules. The CT-pathologic correlations for leukemic infiltration were evaluated in 7 patients. Frequent parenchymal CT findings were thickening of bronchovascular bundles (81.8%), prominence of peripheral pulmonary arteries (81.8%), and non-lobular and non-segmental ground-glass opacities (90.9%). The first two findings were significantly more frequently observed in leukemic infiltration than in the control group, had good interobserver agreement, and corresponded pathologically to leukemic cell infiltration around the pulmonary arteries, bronchi, or bronchioles. Non-lobular and non-segmental ground-glass opacity corresponded to leukemic cell infiltration within alveolar spaces and septa adjacent to the pulmonary arteries or bronchi and also corresponded to hemorrhage, edema, or diffuse alveolar damage. Thickening of bronchovascular bundles and prominence of peripheral pulmonary arteries are CT findings suggestive for leukemic infiltration and correspond to peribronchovascular tumor extension.

HRCT findings of chest complications in patients with leukemia

Abstract. High-resolution CT (HRCT) findings of several chest complications occurring in leukemic patients were reviewed. Although most entities show non-specific HRCT findings including ground-glass opacity and air-space consolidation, characteristic findings are observed in several pulmonary complications including Pneumocystis carinii pneumonia, fungal infections, miliary tuberculosis, leukemic infiltration, pulmonary edema, bronchiolitis obliterans, and bronchiolitis obliterans organizing pneumonia. A combination of these characteristic HRCT findings and the information obtained from the clinical setting may help in achieving a correct diagnosis of chest complications occurring in leukemic patients.

Inhalational lung injury due to nitrogen dioxide : High-resolution computed tomography findings in 3 patients

Chest radiographic and high-resolution computed tomography findings of 3 patients with inhalational lung injury due to nitrogen dioxide were reported. Chest radiographs showed ill-defined round opacities which tended to coalesce in both lung with inner lung predominance. High-resolution computed tomography showed ground-glass attenuation and ill-defined centrilobular nodules distributed predominantly in the inner and middle lung zones. One patient showed progression of opacities, which corresponded to the findings of acute respiratory distress syndrome.

Imaging findings of an intercostal hemangioma.

SUMMARY The authors present the imaging findings in a 44-year-old woman with a rare intercostal hemangioma that originated from the connective tissue between the intercostal muscle and parietal pleura and protruded into the thoracic cavity. The contrast-enhanced computed tomography (CT) showed a markedly enhancing mass, whereas dynamic magnetic resonance (MR) images showed heterogeneous and strong enhancement with incomplete early eccentric enhancement peripherally followed by complete filling-in on delayed scans. The imaging features of CT and MR imaging of a hemangioma may be useful for proper preoperative diagnosis.

Community-acquired pneumonia: a correlative study between chest radiographic and HRCT findings.

PurposeTo elucidate what kinds of lesions tend to be overlooked or misinterpreted and why they were overlooked or misinterpreted on chest radiographs in the diagnosis of community-acquired pneumonia (CAP) by comparing radiographic findings with HRCT findings.Materials and methodsIn 129 patients with CAP (107 bacterial and 22 atypical) and 105 healthy subjects, the chest radiographic findings were correlated with the HRCT findings. The diagnostic accuracy of each chest radiographic finding was evaluated by comparing it with the HRCT finding.ResultsThe false negative rate of radiographic interpretation tended to be higher for nodules and thickening of the bronchial wall, especially in patients with atypical pneumonia. The most frequent reason for false negative interpretations of nodules and bronchial wall thickening was the overlapping of these findings with airspace consolidation or ground-glass opacity (GGO). Thin lesions were the most frequent reasons for the false negative interpretation of airspace consolidation and GGO.ConclusionThe chest radiographic interpretations of GGO and airspace consolidation were influenced by the thickness of lesions, and those of nodules and thickening of bronchial walls were influenced by coexisting GGO and airspace consolidation and may contribute to a misinterpretation of these lesions and an incorrect diagnosis of CAP.