Tamara Babic

Primary inflammatory myofibroblastic tumor of the stomach in an adult woman: a case report and review of the literature

Inflammatory myofibroblastic tumor has been defined as a histologically distinctive lesion with uncertain behaviour. The term inflammatory myofibroblastic tumor more commonly referred to as “pseudostumor ”, denotes a pseudosarcomatous inflammatory lesion that contains spindle cells, myofibroblasts, plasma cells, lymphocytes and histiocytes. It exhibits a variable biological behavior that ranges from frequently benign lesions to more aggressive variants. Inflammatory myofibroblastic tumor mostly occurs in the soft tissue of children and young adults, and the lungs are the most commonly affected site, but it has been recognized that any anatomic localization can be involved. Inflammatory myofibroblastic tumors in adults are very rare, especially in the stomach. We present a case of a 43-year old woman with primary inflammatory myofibiroblastic tumor in the stomach and a review of the literature.

Quality of life of the patients with gastroesophageal reflux disease in Serbia

Gastroesophageal reflux disease (ERD) was often considered as a minor public health problem and its potential severity was not fully recognized by the general public, patients, the health care system, and in some cases health care providers. Data about GERD related HRQoL in eastern European population are scare. The aim of the study was to evaluate the burden of GERD on patients treated in Serbian primary health care. The study included 1091 patients with diagnosed GERD, treated in Serbian primary health care. All patients completed Serbian version of generic self-administered Center for Disease Control and Prevention questionnaire, CDC-HRQoL-4.In our study, 463 (42%) GERD patients self-rated their current health status as fair or poor, 584 (53%) had poor physical health one or more days during the past 30 days, 460 (42%) had poor mental health one or more days for the same time period. Due to disease symptoms 492 (46%) GERD patients felt depressed one or more days during the past 30 days, 581 (54%) felt tired or sleepy during the same time period. In addition, GERD patients had lower scores regarding number of healthy and unhealthy days. The obtained results had demonstrated that in large proportion, GERD impaired patient everyday lives. A better understanding of the relationships between GERD and impaired HRQoL may allow the physicians in primary health care to manage these patients more effectively in the future.