Tamer Yoldaş

Subclinical left ventricular systolic and diastolic dysfunction in type 1 diabetic children and adolescents with good metabolic control

Cardiac dysfunction is a well‐known consequence of diabetes mellitus. This study was designed to assess whether type 1 diabetic children and adolescents with good metabolic control have early echocardiographic signs of subclinical left ventricular dysfunction and whether diabetes duration has any influence, using conventional and nonconventional echocardiographic tools.

Sensitive Cardiac Troponins: Could They Be New Biomarkers in Pediatric Pulmonary Hypertension Due to Congenital Heart Disease?

To analyze the role of sensitive cardiac troponin I (scTnI) and high-sensitive troponin T (hscTnT) in the determination of myocardial injury caused by volume and pressure load due to pulmonary hypertension (PH) and to investigate if these markers may be useful in the management of PH in childhood. Twenty-eight patients with congenital heart disease (CHD) with left to right shunt and PH, 29 patients with CHD with left to right shunt but without PH, and 18 healthy children, in total 75 individuals, were included in the study. All cases were aged between 4 and 36 months. Echocardiographic evaluation was performed in all cases, and invasive hemodynamic investigation was performed in 33 cases. Blood samples were obtained from all cases, for the measurement of brain natriuretic peptide (BNP), pro-brain natriuretic peptide (pro-BNP), sensitive cardiac troponin I (scTnI), and high-sensitive troponin T (hscTnT) levels. The mean BNP, pro-BNP, scTnI, and hsTnT levels were statistically significantly higher in patients with PH than in the patients without PH (p < 0.001). A statistically significant positive correlation was determined between pulmonary artery systolic pressure and scTnI and hscTnT levels (r = 0.34 p = 0.01, r = 0.46 p < 0.001, respectively) levels. Pulmonary hypertension determined in congenital heart diseases triggers myocardial damage independently of increased volume or pressure load and resistance, occurring by disrupting the perfusion via increasing ventricular wall tension and the myocardial oxygen requirement. Serum scTnI and hscTnT levels may be helpful markers to determine the damage associated with PH in childhood.

Massive Pericardial Effusion and Tamponade Can Be a First Sign of Familial Mediterranean Fever

Abstract Cardiac involvement is a rare initial presentation of familial Mediterranean fever (FMF). We described 2 children with massive pericardial effusion and cardiac tamponade, who were later diagnosed as having FMF based on clinical and laboratory findings. Therefore, in children presenting with massive pericardial effusion, FMF should be considered as one of the differential diagnoses. In addition, massive pericardial effusion is a serious clinical condition that requires emergency therapeutic approach including pericardiocenthesis. For medical treatment, colchicine is the first line therapy, but in resistant cases, other anti-inflammatory drugs can be used for extra anti-inflammatory effect.

Persistent left superior vena cava accompanying congenital heart disease in children: Experience of a tertiary care center

This study focuses on determining concomitant persistent left superior vena cava (SVC) in patients with congenital heart disease (CHD).

PP-150 Effect of Pulmonary Hypertension Related Congenital Heart Disease with Left to Right Shunt on the Serum Levels of High Sensitive Cardiac Troponins in Children

The American Journal of Cardiology MARCH 26e29, 2015 11 IN AND C was attempted in 7 of the patients (2 teratoma, 1 papillerfibroelastoma, 1 fetal type rhabdomyoma, 1 TBS associated rhabdomyoma producing left ventricular outflow tract obstruction, 1 cystic tumor with granulomatous inflammation and 1 undiagnosed solid mass). Of the patients 3 died in perioperative period. Conclusion: Most of cardiac tumours during childhood are benign. Spontaneus regression is most probably possible in cases of TBS associated rhabdomyoma. Surgical intervention is only required for children who develop clinical symptoms due to hemodynamic instability.

PP-078 Pericardial Effusion in Childhood: Experience from Tertiary Care Center in Ankara

Pericardial Effusion in Childhood: Experience from Tertiary Care Center in Ankara. Tamer Yoldas, Ozkan Kaya, Şeyma Kayali, Ilker Ertu grul, Vehbi Do gan, Senem Ozgur, Utku Arman Orun, Selmin Karademir, Murat Koc. Department of Pediatric Cardiology, Dr. Sami Ulus Maternity and Children Research and Training Hospital; Department of Pediatric Cardiovascular Surgery, Dr. Sami Ulus Maternity and Children Research and Training