Tamila Shalumova

Zirconium-Mediated Synthesis of Arsaalkene Compounds from Arsines and Isocyanides

An atom-economical synthesis of arsaalkenes via a net coupling of aryl arsines with aryl or alkyl isocyanides at zirconium is presented. Reaction of zirconium arsenido complexes (N3N)ZrAsHAr [N3N = N(CH2CH2NSiMe3)3(3-); Ar = Ph, (2) Mes (3)] with aryl and alkyl isocyanides yields arsaalkene products of the general form (N3N)Zr[NRC(H)═As(Ar)]. Two examples (5: R = Mes, Ar = Ph; 6: R = CH2Ph, Ar = Mes) were structurally characterized. Observation of intermediates in the reaction and structural characterization of the previously reported 1,1-insertion product benzylisocyanide with (N3N)ZrAsPh2 (8), (N3N)Zr[η(2)-C(PPh2)=NCH2Ph] (9), support the mechanistic hypothesis that these reactions occur via 1,1-insertion followed by rearrangement.

Development of a 2-Aza-Cope-[3+2] Dipolar Cycloaddition Strategy for the Synthesis of Quaternary Proline Scaffolds

A one-pot multicomponent procedure for the synthesis of highly functionalized pyrrolidine rings through a domino 2-aza-Cope-[3 + 2] dipolar cycloaddition sequence has been demonstrated. This protocol was found to be both high-yielding and stereoselective for the endo cycloadduct.

5-(Hy­droxy­meth­yl)furan-2-carbaldehyde

The title compound (HMF), C6H6O3, is one of the products of acid-catalyzed dehydration of high-fructose corn syrup, and has been shown to be toxic to honey bees. The compound was crystallized at 276 K, and it was found that the two independent molecules in the asymmetric unit form an infinite O—H⋯O hydrogen-bonding chain that is linked into a three-dimensional network structure by weak intermolecular C—H⋯O contacts.

Dimeth­yl(2,2′:6′,2′′-terpyridine-κ3N,N′,N′′)zinc(II)

The title compound, [Zn(CH3)2(C15H11N3)], was synthesized by the addition of dimethylzinc to 2,2′:6′,2′′-terpyridine and was crystallized by the slow evaporation of THF. The pentacoordinate ZnII atom, lying on a twofold rotation axis, displays a distorted trigonal-bipyramidal geometry, with two terminal N atoms at the axial positions and the central N atom and two methyl C atoms at the equatorial positions.