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Featured researches published by Tamotsu Morita.


Photochemistry and Photobiology | 1988

INHIBITORY EFFECTS OF ETHANOL ON THE PHOTODYNAMIC CELL INACTIVATION AND PETITE INDUCTION BY EUFLAVINE IN YEAST, Saccharomyces cerevisiae

M. Tsuchiya; Yoshihisa Iwamoto; Toshiyuki Masuzawa; Tadayori Shimizu; Tamotsu Morita; Yasutake Yanagihara

Abstract— Effects of active oxygen scavengers on cell inactivation and petite induction of yeast by the photodynamic action of euflavine were examined. Histidine, sodium azide, 1,3‐diphenyl‐isobenzofuran and p‐carotene, which are singlet oxygen scavengers, inhibited photodynamic cell killing. Histidine and sodium azide inhibited petite induction, too. These results suggested that photobiological effects of euflavine are induced via singlet oxygen‐mediated Type II reaction process. In this work, however, we found that ethanol, which is reported to be a hydroxyl radical scavenger, notably inhibited photodynamic cell inactivation and petite induction by euflavine. Inhibition of petite induction was increased with increasing concentration of ethanol. Decrease of absorbance of euflavine by irradiation was also inhibited by the addition of ethanol.


Biological & Pharmaceutical Bulletin | 1993

Photodynamic DNA strand breaking activities of acridine compounds

Yoshihisa Iwamoto; Toshio Itoyama; Kyoko Yasuda; Tamotsu Morita; Tadayori Shimizu; Toshiyuki Masuzawa; Yasutake Yanagihara


Chemical & Pharmaceutical Bulletin | 1989

Mutagenicity Tests with a Permeable Mutant of Yeast on Carcinogens Showing False-Negative in Salmonella Assay

Tamotsu Morita; Yoshihisa Iwamoto; Tadayori Shimizu; Toshiyuki Masuzawa; Yasutake Yanagihara


Japanese Journal of Microbiology | 1963

INDUCTION OF RESPIRATION-DEFICIENT MUTANT OF SACCHAROMYCES CEREVISIAE BY CARCINOGENIC AGENT, 4-NITROQUINOLINE N-OXIDE AND THE EXISTENCE OF TOXOHORMONE-LIKE FACTOR IN THE MUTANT

Ichiji Mifuchi; Tamotsu Morita; Yasutake Yanagihara; Masaharu Hosoi; Mikio Nishida


Japanese Journal of Microbiology | 1965

EFFECT OF METHYLENE BLUE ON THE ACTION OF 4-NITROQUINOLINE N-OXIDE AND ACRIFLAVINE IN INDUCING RESPIRATION-DEFICIENT MUTANTS OF SACCHAROMYCES CEREVISIAE

Tamotsu Morita; Ichiji Mifuchi


Chemical & Pharmaceutical Bulletin | 1989

Monoclonal antibody against Leptospira interrogans serovar canicola.

Toshiyuki Masuzawa; Tomohiko Sekiguchi; Tadayori Shimizu; Yoshihisa Iwamoto; Tamotsu Morita; Ichiji Mifuchi; Yasutake Yanagihara


Journal of General and Applied Microbiology | 1978

LOSS AND RETENTION OF MITOCHONDRIAL DRUG RESISTANCE IN RHO- MUTANTS OF YEAST INDUCED BY 4-NITROQUINOLINE 1-OXIDE AND ETHIDIUM BROMIDE

Masahito Fukunaga; Tamotsu Morita; Ichiji Mifuchi


Journal of General and Applied Microbiology | 2001

Selection of more appropriate PCR primer pairs for improved efficiency in detecting Norwalk-like virus (NLV) RNA

Hirotaka Naitou; Tamotsu Morita


Biological & Pharmaceutical Bulletin | 1998

Qualitative and quantitative detection of cytomegalovirus DNA in sera by PCR as a clinical marker.

Hirotaka Naitou; Jun-ichi Mimaya; Yasuo Horikoshi; Yoshifumi Takashima; Koji Amano; Tamotsu Morita


Biological & Pharmaceutical Bulletin | 1997

Quantitative Detection of Human Immunodeficiency Virus Type 1 (HIV-1) RNA by PCR and Use as a Prognostic Marker and for Evaluating Antiretroviral Therapy

Hirotaka Naitou; Jun-ichi Mimaya; Yasuo Horikoshi; Tamotsu Morita

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Masahito Fukunaga

University of Alabama at Birmingham

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Etsuo Oishi

University of Shizuoka

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