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Dive into the research topics where Tanekazu Nadai is active.

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Featured researches published by Tanekazu Nadai.


Journal of Pharmacy and Pharmacology | 1985

Characterization of enhanced intestinal permeability. Electrophysiological study on the effects of diclofenac and ethylenediaminetetraacetic acid

Shinji Yamashita; Hidetaka Saitoh; Kunio Nakanishi; Mikio Masada; Tanekazu Nadai; Toshikoro Kimura

The mechanism of the enhancing effects of diclofenac sodium and disodium ethylenediaminetetraacetate (EDTA) on intestinal permeability to sulphanilic acid were investigated in the rat isolated jejunum by an electrophysiological technique. The results suggested that diclofenac sodium increased the mucosal‐to‐serosal flux rate of sulphanilic acid by enhancing both transcellular and paracellular permeabilities while the effect of EDTA was located only in the paracellular pathway.


Chemical & Pharmaceutical Bulletin | 1981

The use of chitin and chitosan as drug carriers.

Shozo Miyazaki; Kuniaki Ishii; Tanekazu Nadai


Journal of Pharmaceutical Sciences | 1981

Precaution on Use of Hydrochloride Salts in Pharmaceutical Formulation

Shozo Miyazaki; Midori Oshiba; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1980

Drug-carrier property of albumin microspheres in chemotherapy. IV. Antitumor effect of single-shot or multiple-shot administration of microsphere-entrapped 5-fluorouracil on Ehrlich ascites or solid tumor in mice.

Yasunori Morimoto; Masayuki Akimoto; Kenji Sugibayashi; Tanekazu Nadai; Yoshio Kato


Chemical & Pharmaceutical Bulletin | 1980

Interaction of drugs with bile components. II. Effect of bile on the absorption of indomethacin and phenylbutazone in rats.

Shozo Miyazaki; Tomohiro Yamahira; Hitomi Inoue; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1984

Effect of nonsteroidal anti-inflammatory drugs on the permeability of the rectal mucosa.

Kunio Nakanishi; Akio Ogata; Mikio Masada; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1984

Mechanism of the Enhancement of Rectal Permeability of Drugs by Nonsteroidal Anti-inflammatory Drugs

Kunio Nakanishi; Hidetaka Saitoh; Mikio Masada; Akira Tatematsu; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1983

Effect of Pharmaceutical Adjuvants on the Rectal Permeability of Drugs. II. Effect of Tween-Type Surfactants on the Permeability of Drugs in the Rat Rectum

Kunio Nakanishi; Mikio Masada; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1981

Controlled release of prednisolone from ethylene-vinyl acetate copolymer matrix.

Shozo Miyazaki; Kuniaki Ishii; Tanekazu Nadai


Chemical & Pharmaceutical Bulletin | 1980

Use of Fibrin Film as a Carrier for Drug Delivery : In Vitro Drug Permeabilities of Fibrin Film

Shozo Miyazaki; Tanekazu Nadai

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