Tanji Suzuki

Correlations of peritoneal interleukin-6, serum beta-2 microglobulin and urinary beta-2 microglobulin after elective abdominal surgery

Postoperative peritoneal interleukin‐6 (P‐IL‐6), serum beta‐2 microglobulin (SBMG) and urinary beta‐2 microglobulin (UBMG) concentrations were examined in 33 patients who underwent various types of abdominal surgery. Similar time‐dependent changes in SBMG and UBMG were observed in five other patients who underwent abdominal surgery. SBMG decreased the first day after the operation (1POD), then increased and reached the preoperative level by the third day after the operation (3POD). UBMG started to increase 1POD, reached the maximum 3POD, then decreased. The 1POD SBMG concentration was significantly correlated with P‐IL‐6, and 3POD UBMG was also significantly correlated with P‐IL‐6. These findings indicate that serum and urinary beta‐2 microglobulin concentrations are closely correlated with P‐IL‐6.

A Rare Case of Huge Gastric Carcinoma with Extramural Growth

A rare case of gastric carcinoma which grew extramurally and invaded into the transverse mesocolon and pancreas is reported. The patient was a 67-year-old female, complaining of anorexia, weightloss and abdominal distension. She was diagnosed as gastric carcinoma with extramural growth. Intraoperative findings included a fistsized, elastic hard tumor on the greater curvature that infiltrated into the transverse mesocolon and pancreas head(S3P0H0N1 stage4). Histopathologically, it was diagnosed as a poorly differentiated adenocarcinoma. The main tumor invaded deeply into the subserosal soft tissue(10× 8.5 × 6.5 cm). However upper part of the tumor appeared on the mucosal surface as a small erosion(1.2×0.9 cm in diameter).