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Circulation | 2012

Heart Disease and Stroke Statistics—2012 Update A Report From the American Heart Association

Véronique L. Roger; Alan S. Go; Donald M. Lloyd-Jones; Emelia J. Benjamin; Jarett D. Berry; William B. Borden; Dawn M. Bravata; Shifan Dai; Earl S. Ford; Caroline S. Fox; Heather J. Fullerton; Cathleen Gillespie; Susan M. Hailpern; John A. Heit; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; Diane M. Makuc; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Claudia S. Moy; Dariush Mozaffarian; Michael E. Mussolino; Graham Nichol; Nina P. Paynter; Elsayed Z. Soliman

Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e3 1. About These Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e7 2. American Heart Associations 2020 Impact Goals. . . . . . . . . . . . . . . . .e10 3. Cardiovascular Diseases . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . .e21 4. Subclinical Atherosclerosis . . . . . . . . . . . . . . . . . . . . .e45 5. Coronary Heart Disease, Acute Coronary Syndrome, and Angina Pectoris . . . . . . . . .e54 6. Stroke (Cerebrovascular Disease) . . . . . . . . . . . . . . . . . . . . . . . . . . . .e68 7. High Blood Pressure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .e88 8. Congenital Cardiovascular Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . .e97 9. Cardiomyopathy and Heart Failure . . . . . . . . . . . . . . . . . . . . . . . . . . . .e102 10. Disorders …


Circulation | 2013

Heart Disease and Stroke Statistics—2013 Update A Report From the American Heart Association

Alan S. Go; Dariush Mozaffarian; Véronique L. Roger; Emelia J. Benjamin; Jarett D. Berry; William B. Borden; Dawn M. Bravata; Shifan Dai; Earl S. Ford; Caroline S. Fox; Sheila Franco; Heather J. Fullerton; Cathleen Gillespie; Susan M. Hailpern; John A. Heit; Virginia J. Howard; Mark D. Huffman; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; David J. Magid; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy; Michael E. Mussolino

Author(s): Go, Alan S; Mozaffarian, Dariush; Roger, Veronique L; Benjamin, Emelia J; Berry, Jarett D; Borden, William B; Bravata, Dawn M; Dai, Shifan; Ford, Earl S; Fox, Caroline S; Franco, Sheila; Fullerton, Heather J; Gillespie, Cathleen; Hailpern, Susan M; Heit, John A; Howard, Virginia J; Huffman, Mark D; Kissela, Brett M; Kittner, Steven J; Lackland, Daniel T; Lichtman, Judith H; Lisabeth, Lynda D; Magid, David; Marcus, Gregory M; Marelli, Ariane; Matchar, David B; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Mussolino, Michael E; Nichol, Graham; Paynter, Nina P; Schreiner, Pamela J; Sorlie, Paul D; Stein, Joel; Turan, Tanya N; Virani, Salim S; Wong, Nathan D; Woo, Daniel; Turner, Melanie B; American Heart Association Statistics Committee and Stroke Statistics Subcommittee


Circulation | 2011

Heart Disease and Stroke Statistics—2011 Update A Report From the American Heart Association

Véronique L. Roger; Alan S. Go; Donald M. Lloyd-Jones; Robert J. Adams; Jarett D. Berry; Todd M. Brown; Mercedes R. Carnethon; Shifan Dai; Giovanni de Simone; Earl S. Ford; Caroline S. Fox; Heather J. Fullerton; Cathleen Gillespie; Kurt J. Greenlund; Susan M. Hailpern; John A. Heit; P. Michael Ho; Virginia J. Howard; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; Diane M. Makuc; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Mary M. McDermott; James B. Meigs; Claudia S. Moy

Rosamond, Paul D. Sorlie, Randall S. Stafford, Tanya N. Turan, Melanie B. Turner, Nathan D. Dariush Mozaffarian, Michael E. Mussolino, Graham Nichol, Nina P. Paynter, Wayne D. Ariane Marelli, David B. Matchar, Mary M. McDermott, James B. Meigs, Claudia S. Moy, Lackland, Judith H. Lichtman, Lynda D. Lisabeth, Diane M. Makuc, Gregory M. Marcus, John A. Heit, P. Michael Ho, Virginia J. Howard, Brett M. Kissela, Steven J. Kittner, Daniel T. Caroline S. Fox, Heather J. Fullerton, Cathleen Gillespie, Kurt J. Greenlund, Susan M. Hailpern, Todd M. Brown, Mercedes R. Carnethon, Shifan Dai, Giovanni de Simone, Earl S. Ford, Véronique L. Roger, Alan S. Go, Donald M. Lloyd-Jones, Robert J. Adams, Jarett D. Berry, Association 2011 Update : A Report From the American Heart −− Heart Disease and Stroke Statistics


Circulation | 2014

Heart Disease and Stroke Statistics—2014 Update A Report From the American Heart Association

Alan S. Go; Dariush Mozaffarian; Véronique L. Roger; Emelia J. Benjamin; Jarett D. Berry; Michael J. Blaha; Shifan Dai; Earl S. Ford; Caroline S. Fox; Sheila Franco; Heather J. Fullerton; Cathleen Gillespie; Susan M. Hailpern; John A. Heit; Virginia J. Howard; Mark D. Huffman; Suzanne E. Judd; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; Rachel H. Mackey; David J. Magid; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy

Author(s): Go, Alan S; Mozaffarian, Dariush; Roger, Veronique L; Benjamin, Emelia J; Berry, Jarett D; Blaha, Michael J; Dai, Shifan; Ford, Earl S; Fox, Caroline S; Franco, Sheila; Fullerton, Heather J; Gillespie, Cathleen; Hailpern, Susan M; Heit, John A; Howard, Virginia J; Huffman, Mark D; Judd, Suzanne E; Kissela, Brett M; Kittner, Steven J; Lackland, Daniel T; Lichtman, Judith H; Lisabeth, Lynda D; Mackey, Rachel H; Magid, David J; Marcus, Gregory M; Marelli, Ariane; Matchar, David B; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Mussolino, Michael E; Neumar, Robert W; Nichol, Graham; Pandey, Dilip K; Paynter, Nina P; Reeves, Matthew J; Sorlie, Paul D; Stein, Joel; Towfighi, Amytis; Turan, Tanya N; Virani, Salim S; Wong, Nathan D; Woo, Daniel; Turner, Melanie B; American Heart Association Statistics Committee and Stroke Statistics Subcommittee


Circulation | 2010

Executive summary: Heart disease and stroke statistics-2016 update: A Report from the American Heart Association

Dariush Mozaffarian; Emelia J. Benjamin; Alan S. Go; Donna K. Arnett; Michael J. Blaha; Mary Cushman; Sandeep R. Das; Sarah D. de Ferranti; Jean-Pierre Després; Heather J. Fullerton; Virginia J. Howard; Mark D. Huffman; Carmen R. Isasi; Monik C. Jiménez; Suzanne E. Judd; Brett Kissela; Judith H. Lichtman; Lynda D. Lisabeth; Simin Liu; Rh Mackey; David J. Magid; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy; Paul Muntner; Michael E. Mussolino; Khurram Nasir; Robert W. Neumar; Graham Nichol; Latha Palaniappan

Author(s): Writing Group Members; Mozaffarian, Dariush; Benjamin, Emelia J; Go, Alan S; Arnett, Donna K; Blaha, Michael J; Cushman, Mary; Das, Sandeep R; de Ferranti, Sarah; Despres, Jean-Pierre; Fullerton, Heather J; Howard, Virginia J; Huffman, Mark D; Isasi, Carmen R; Jimenez, Monik C; Judd, Suzanne E; Kissela, Brett M; Lichtman, Judith H; Lisabeth, Lynda D; Liu, Simin; Mackey, Rachel H; Magid, David J; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Muntner, Paul; Mussolino, Michael E; Nasir, Khurram; Neumar, Robert W; Nichol, Graham; Palaniappan, Latha; Pandey, Dilip K; Reeves, Mathew J; Rodriguez, Carlos J; Rosamond, Wayne; Sorlie, Paul D; Stein, Joel; Towfighi, Amytis; Turan, Tanya N; Virani, Salim S; Woo, Daniel; Yeh, Robert W; Turner, Melanie B; American Heart Association Statistics Committee; Stroke Statistics Subcommittee


Circulation | 2016

Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association

Dariush Mozaffarian; Emelia J. Benjamin; Alan S. Go; Donna K. Arnett; Michael J. Blaha; Mary Cushman; Sandeep R. Das; Sarah D. de Ferranti; Jean-Pierre Després; Heather J. Fullerton; Virginia J. Howard; Mark D. Huffman; Carmen R. Isasi; Monik Jimenez; Suzanne E. Judd; Brett Kissela; Judith H. Lichtman; Lynda D. Lisabeth; Simin Liu; Rachel H. Mackey; David J. Magid; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy; Paul Muntner; Michael E. Mussolino; Khurram Nasir; Robert W. Neumar; Graham Nichol; Latha Palaniappan

Author(s): Writing Group Members; Mozaffarian, Dariush; Benjamin, Emelia J; Go, Alan S; Arnett, Donna K; Blaha, Michael J; Cushman, Mary; Das, Sandeep R; de Ferranti, Sarah; Despres, Jean-Pierre; Fullerton, Heather J; Howard, Virginia J; Huffman, Mark D; Isasi, Carmen R; Jimenez, Monik C; Judd, Suzanne E; Kissela, Brett M; Lichtman, Judith H; Lisabeth, Lynda D; Liu, Simin; Mackey, Rachel H; Magid, David J; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Muntner, Paul; Mussolino, Michael E; Nasir, Khurram; Neumar, Robert W; Nichol, Graham; Palaniappan, Latha; Pandey, Dilip K; Reeves, Mathew J; Rodriguez, Carlos J; Rosamond, Wayne; Sorlie, Paul D; Stein, Joel; Towfighi, Amytis; Turan, Tanya N; Virani, Salim S; Woo, Daniel; Yeh, Robert W; Turner, Melanie B; American Heart Association Statistics Committee; Stroke Statistics Subcommittee


Circulation | 2015

Heart Disease and Stroke Statistics—2015 Update A Report From the American Heart Association

Dariush Mozaffarian; Emelia J. Benjamin; Alan S. Go; Donna K. Arnett; Michael J. Blaha; Mary Cushman; Sarah D. de Ferranti; Jean-Pierre Després; Heather J. Fullerton; Virginia J. Howard; Mark D. Huffman; Suzanne E. Judd; Brett Kissela; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; Simin Liu; Rachel H. Mackey; David B. Matchar; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy; Paul Muntner; Michael E. Mussolino; Khurram Nasir; Robert W. Neumar; Graham Nichol; Latha Palaniappan; Dilip K. Pandey; Mathew J. Reeves

STRIDE (Stanford Translational Research Integrated Database Environment) is a research and development project at Stanford University to create a standards-based informatics platform supporting clinical and translational research. STRIDE consists of three integrated components: a clinical data warehouse, based on the HL7 Reference Information Model (RIM), containing clinical information on over 1.3 million pediatric and adult patients cared for at Stanford University Medical Center since 1995; an application development framework for building research data management applications on the STRIDE platform and a biospecimen data management system. STRIDEs semantic model uses standardized terminologies, such as SNOMED, RxNorm, ICD and CPT, to represent important biomedical concepts and their relationships. The system is in daily use at Stanford and is an important component of Stanford Universitys CTSA (Clinical and Translational Science Award) Informatics Program.on behalf of the American Heart Association Statistics Committee and Stroke Statistics Nathan D. Wong, Daniel Woo and Melanie B. Turner Elsayed Z. Soliman, Paul D. Sorlie, Nona Sotoodehnia, Tanya N. Turan, Salim S. Virani, Claudia S. Moy, Dariush Mozaffarian, Michael E. Mussolino, Graham Nichol, Nina P. Paynter, Lynda D. Lisabeth, Diane M. Makuc, Gregory M. Marcus, Ariane Marelli, David B. Matchar, Lichtman, Virginia J. Howard, Brett M. Kissela, Steven J. Kittner, Daniel T. Lackland, Judith H. Caroline S. Fox, Heather J. Fullerton, Cathleen Gillespie, Susan M. Hailpern, John A. Heit, Benjamin, Jarett D. Berry, William B. Borden, Dawn M. Bravata, Shifan Dai, Earl S. Ford, Writing Group Members, Véronique L. Roger, Alan S. Go, Donald M. Lloyd-Jones, Emelia J. Association 2012 Update : A Report From the American Heart −− Heart Disease and Stroke StatisticsHeart Disease, Stroke and other Cardiovascular Diseases • Cardiovascular disease is the leading global cause of death, accounting for 17.3 million deaths per year, a number that is expected to grow to more than 23.6 million by 2030. • In 2008, cardiovascular deaths represented 30 percent of all global deaths, with 80 percent of those deaths taking place in lowand middle-income countries. • Nearly 787,000 people in the U.S. died from heart disease, stroke and other cardiovascular diseases in 2011. That’s about one of every three deaths in America. • About 2,150 Americans die each day from these diseases, one every 40 seconds. • Cardiovascular diseases claim more lives than all forms of cancer combined. • About 85.6 million Americans are living with some form of cardiovascular disease or the after-effects of stroke. • Direct and indirect costs of cardiovascular diseases and stroke total more than


Stroke | 2011

Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Karen L. Furie; Scott E. Kasner; Robert J. Adams; Gregory W. Albers; Ruth L. Bush; Susan C. Fagan; Jonathan L. Halperin; S. Claiborne Johnston; Irene Katzan; Walter N. Kernan; Pamela H. Mitchell; Bruce Ovbiagele; Yuko Y. Palesch; Ralph L. Sacco; Lee H. Schwamm; Sylvia Wassertheil-Smoller; Tanya N. Turan; Deidre Wentworth

320.1 billion. That includes health expenditures and lost productivity. • Nearly half of all African-American adults have some form of cardiovascular disease, 48 percent of women and 46 percent of men. • Heart disease is the No. 1 cause of death in the world and the leading cause of death in the United States, killing over 375,000 Americans a year. • Heart disease accounts for 1 in 7 deaths in the U.S. • Someone in the U.S. dies from heart disease about once every 90 seconds.Author(s): Mozaffarian, Dariush; Benjamin, Emelia J; Go, Alan S; Arnett, Donna K; Blaha, Michael J; Cushman, Mary; de Ferranti, Sarah; Despres, Jean-Pierre; Fullerton, Heather J; Howard, Virginia J; Huffman, Mark D; Judd, Suzanne E; Kissela, Brett M; Lackland, Daniel T; Lichtman, Judith H; Lisabeth, Lynda D; Liu, Simin; Mackey, Rachel H; Matchar, David B; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Muntner, Paul; Mussolino, Michael E; Nasir, Khurram; Neumar, Robert W; Nichol, Graham; Palaniappan, Latha; Pandey, Dilip K; Reeves, Mathew J; Rodriguez, Carlos J; Sorlie, Paul D; Stein, Joel; Towfighi, Amytis; Turan, Tanya N; Virani, Salim S; Willey, Joshua Z; Woo, Daniel; Yeh, Robert W; Turner, Melanie B; American Heart Association Statistics Committee and Stroke Statistics Subcommittee


Circulation | 2010

Executive Summary: Heart Disease and Stroke Statistics—2013 Update

Alan S. Go; Dariush Mozaffarian; Véronique L. Roger; Emelia J. Benjamin; Jarett D. Berry; William B. Borden; Dawn M. Bravata; Shifan Dai; Earl S. Ford; Caroline S. Fox; Sheila Franco; Heather J. Fullerton; Cathleen Gillespie; Susan M. Hailpern; John A. Heit; Virginia J. Howard; Mark D. Huffman; Brett Kissela; Steven J. Kittner; Daniel T. Lackland; Judith H. Lichtman; Lynda D. Lisabeth; David J. Magid; Gregory M. Marcus; Ariane J. Marelli; David B. Matchar; Darren K. McGuire; Emile R. Mohler; Claudia S. Moy; Michael E. Mussolino

The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of ischemic stroke or transient ischemic attack. Evidence-based recommendations are included for the control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke. Further recommendations are provided for the prevention of recurrent stroke in a variety of other specific circumstances, including arterial dissections; patent foramen ovale; hyperhomocysteinemia; hypercoagulable states; sickle cell disease; cerebral venous sinus thrombosis; stroke among women, particularly with regard to pregnancy and the use of postmenopausal hormones; the use of anticoagulation after cerebral hemorrhage; and special approaches to the implementation of guidelines and their use in high-risk populations.


The New England Journal of Medicine | 2011

Stenting versus aggressive medical therapy for intracranial arterial stenosis

Marc I. Chimowitz; Michael J. Lynn; Colin P. Derdeyn; Tanya N. Turan; David Fiorella; Bethany F Lane; L. Scott Janis; Helmi L. Lutsep; Stanley L. Barnwell; Michael F. Waters; Brian L. Hoh; J. Maurice Hourihane; Elad I. Levy; Andrei V. Alexandrov; Mark R. Harrigan; David Chiu; Richard Klucznik; Joni Clark; Cameron G. McDougall; Mark Johnson; G. Lee Pride; Michel T. Torbey; Osama O. Zaidat; Zoran Rumboldt; Harry J. Cloft

Author(s): Go, Alan S; Mozaffarian, Dariush; Roger, Veronique L; Benjamin, Emelia J; Berry, Jarett D; Borden, William B; Bravata, Dawn M; Dai, Shifan; Ford, Earl S; Fox, Caroline S; Franco, Sheila; Fullerton, Heather J; Gillespie, Cathleen; Hailpern, Susan M; Heit, John A; Howard, Virginia J; Huffman, Mark D; Kissela, Brett M; Kittner, Steven J; Lackland, Daniel T; Lichtman, Judith H; Lisabeth, Lynda D; Magid, David; Marcus, Gregory M; Marelli, Ariane; Matchar, David B; McGuire, Darren K; Mohler, Emile R; Moy, Claudia S; Mussolino, Michael E; Nichol, Graham; Paynter, Nina P; Schreiner, Pamela J; Sorlie, Paul D; Stein, Joel; Turan, Tanya N; Virani, Salim S; Wong, Nathan D; Woo, Daniel; Turner, Melanie B; American Heart Association Statistics Committee and Stroke Statistics Subcommittee

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Marc I. Chimowitz

Medical University of South Carolina

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L. Scott Janis

National Institutes of Health

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Claudia S. Moy

National Institutes of Health

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Daniel T. Lackland

Centers for Disease Control and Prevention

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Virginia J. Howard

Indiana University Bloomington

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