Taro Masuda

STUDIES ON THE CHEMOTHERAPY OF LEPROSY: (XXI) ONSET SUPPRESSING ACTION OF ANTITUMOR AGENTS AND ANTIBACTERIALS IN MURINE LEPROSY@@@第21報 抗腫瘍性物質竝に二,三抗菌性物質 の鼠癩発症抑制作用

Antitumor agents, as Actinomycin, Carzinophilin, Sarkomycin, Azan, Nitromin and Mitomycin were administering in a dose of 1/3o mouse LD50 for 4 months but there was no suppression of onset of murine leprosy. Oxythiamin, sulfathiazole, Terramycin also had no onset suppressing action. A derivative of INAH, salcylaldehyde isonicotinyl hydrazone, completely suppressed onset of murine leprosy when administered in a large dose (150 mg/kg).