Tavo Romann
University of Tartu
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Publication
Featured researches published by Tavo Romann.
Molecular Pharmaceutics | 2017
Liis Preem; Mohammad Mahmoudzadeh; Marta Putrinš; Andres Meos; Ivo Laidmäe; Tavo Romann; Jaan Aruväli; Riinu Härmas; Artturi Koivuniemi; Alex Bunker; Tanel Tenson; Karin Kogermann
Antibacterial drug-loaded electrospun nano- and microfibrous dressings are of major interest as novel topical drug delivery systems in wound care. In this study, chloramphenicol (CAM)-loaded polycaprolactone (PCL) and PCL/poly(ethylene oxide) (PEO) fiber mats were electrospun and characterized in terms of morphology, drug distribution, physicochemical properties, drug release, swelling, cytotoxicity, and antibacterial activity. Computational modeling together with physicochemical analysis helped to elucidate possible interactions between the drug and carrier polymers. Strong interactions between PCL and CAM together with hydrophobicity of the system resulted in much slower drug release compared to the hydrophilic ternary system of PCL/PEO/CAM. Cytotoxicity studies confirmed safety of the fiber mats to murine NIH 3T3 cells. Disc diffusion assay demonstrated that both fast and slow release fiber mats reached effective concentrations and had similar antibacterial activity. A biofilm formation assay revealed that both blank matrices are good substrates for the bacterial attachment and formation of biofilm. Importantly, prolonged release of CAM from drug-loaded fibers helps to avoid biofilm formation onto the dressing and hence avoids the treatment failure.
Optik | 2018
Ardi Loot; I. Sildos; Valter Kiisk; Tavo Romann; V. Hizhnyakov
Abstract The realization of efficient and miniature source of entangled photon pairs stills remains a challenge. In this work, we experimentally studied the possibility to enhance the process of spontaneous parametric down-conversion by surface plasmon polaritons. The details of the experimental setup will be discussed along with theoretical calculations of the enhancement factor.
Electrochimica Acta | 2014
Tavo Romann; Ove Oll; Piret Pikma; H. Tamme; Enn Lust
Journal of The Electrochemical Society | 2013
Thomas Thomberg; Tauno Tooming; Tavo Romann; Rasmus Palm; Alar Jänes; Enn Lust
Journal of Power Sources | 2016
M. Härmas; Thomas Thomberg; Heisi Kurig; Tavo Romann; Alar Jänes; Enn Lust
Journal of Electroanalytical Chemistry | 2013
K. Tõnurist; Thomas Thomberg; Alar Jänes; Tavo Romann; Väino Sammelselg; Enn Lust
Electrochemistry Communications | 2012
Tavo Romann; Ove Oll; Piret Pikma; Enn Lust
Electrochemistry Communications | 2010
Alar Jänes; Heisi Kurig; Tavo Romann; Enn Lust
Journal of Power Sources | 2015
Tavo Romann; Ove Oll; Piret Pikma; Kalle Kirsimäe; Enn Lust
Carbon | 2016
Heisi Kurig; M. Russina; Indrek Tallo; Miriam Siebenbürger; Tavo Romann; Enn Lust