Tetsuro Fujita

The effect of two new peptide antibiotics, the hypelcins, on mitochondrial function.

The action on mitochondria of 3 peptide antibiotics, hypelcin-A, hypelcin-B, and alamethicin, was examined. The results showed that they are unique uncouplers of oxidative phosphorylation, with the same mechanism of action.

Four new iridoid glucoside p-coumaroyl esters from Ajuga decumbens

Abstract From the methanolic extract of the dried whole plant ofAjuga decumbens, four new iridoid glucosidecis- andtrans-p-coumaroyl esters, decumbeside A (1), B (2), C (7) and D (8) were isolated together with the known reptoside (6) and 8-acetylharpagide (9). The structures of the new compounds have been elucidated on the basis of spectroscopic and chemical evidence.

Structure of inflexinol, a new cytotoxic diterpene from Rabdosia inflexa

Abstract From the leaves of Rabdosia inflexa a new cytotoxic diterpenoid, inflexinol was isolated, together with the known inflexin, and the structure was established as ent-kaur-16-en-15-one-1α,3α,6β,11β-tetraol 1,3-diacetate.

Rabdoternins D-G, ent-7β,20-epoxykaurenes from Rabdosia ternifolia

Abstract Examination of the diterpenoid constituents of the dried leaves of Rabdosia ternifolia led to the isolation of four new diterpenoids, named rabdoternins D-G. The structures were elucidated on the basis of spectroscopic and chemical evidence.

Ent-kaurenoids from Rabdosia umbrosa

Abstract Five new ent -kaurenoids have been isolated from the aerial parts of Rabdosia umbrosa together with the known compounds, kamebanin and kamebakaurin. The structures of new compounds have been determined on the basis of spectroscopic and chemical evidence.

Structure of rabdolatifolin, a diterpenoid from Rabdosia umbrosa var. Latifolia

Abstract From the aerial part of Rabdosia umbrosa var. latifolia , a new diterpenoid, rabdolatifolin, was isolated together with the known compounds, shi

Monoterpene glucosides having a cross conjugated dienone system from Spiraea cantoniensis

Abstract From the dried leaves of Spiraea cantoniensis , three monoterpene glucosides were isolated and the structures were elucidated on the basis of the spectroscopic evidence. Two of the three isolated compounds have a unique cross conjugated dienone system.

Bitter diterpenoids from Isodon shikokianus var. Intermedius

Abstract Four new diterpenoids were isolated from the aerial parts of Isodon shikokianus var. intermedius . The structures of two of them, shikodokaurin A and B, were established.