Tetsuro Ogaki

Cerebral oxygenation during intermittent supramaximal exercise

This study examined cerebral deoxygenation during intermittent supramaximal exercise in six healthy male subjects (age: 27.2 +/- 0.6 years (mean +/- S.E.). The subjects performed seven times exercise at an intensity corresponding to 150% of maximal oxygen uptake (VO2max) on cycle ergometer (30 s exercise/15 s rest). Cerebral oxygenation was measured by near-infrared spectroscopy (NIRS). The peak blood lactate concentration after exercise was 15.3 +/- 0.2 mmol/l. Cerebral oxygenation increased in first repetition compared with at rest (+ 5.7 +/- 0.6 microM; P < 0.05), but then decreased with time. Thus, in the last repetition cerebral oxygenation was - 8.5 +/- 0.4 microM (P < 0.05). There was no significant change in arterial oxygen saturation (99.6 +/- at rest, 98.4 +/- 0.2 at the final set of intermittent exercise), and there was no correlated change in end-tidal CO2 concentration with cerebral oxygenation (P > 0.05). These findings suggest that the fatigue resulting from dynamic severe exercise related to a decrease in the cerebral oxygenation level.

Seroprevalence of Helicobacter pylori infection in Nepal: Low prevalence in an isolated rural village

Objective To determine the seroprevalence of Helicobacter pylori infection in Nepal. Design H. pylori infection was identified using a specific and sensitive enzyme-linked immunosorbent assay for anti-H. pylori immunoglobulin G. Study population Serum samples were collected from 1142 inhabitants (age range 4–93 years) from two villages: Kotyang, a rural isolated village (250 men, 210 women) and Bhadrakali, a suburban village of Kathmandu (334 men, 348 women). Results The overall prevalence of H. pylori infection was 56.8%, while a significantly higher prevalence was found in the suburban village (Bhadrakali; 67.2%) than in the rural village (Kotyang; 41.5%). This difference was generally reflected by the infection rate in the 10–14-year-old age-group (Bhadrakali, 60% compared with Kotyang, 22.2%). The prevalence of infection significantly increased with age, while no significant difference was found in the prevalence of infection by gender. There was no difference in H. pylori positivity between individuals with and without upper abdominal symptoms in both villages. Conclusion There was a significant regional difference in the seroprevalence of H. pylori within Nepal, which showed lower prevalence in an isolated rural village. This difference was mainly caused by the different acquisition rate in teenagers, thus indicating that the teenage lifestyle of this particular environment seemed to be the major determinant in the acquisition of H. pylori infection in the population.

Plasma sulpho-conjugated catecholamine dynamics up to 8 h after 60-min exercise at 50% and 70% maximal oxygen uptakes

AbstractThe prolonged effects of steady-state exercise and meals on plasma sulpho-conjugated catecholamines (CA) after exercise were examined. Seven male subjects exercised on 2 separate days for 60 min at 50% and 70% of maximal oxygen uptake (

Pre-cooling with intermittent ice ingestion lowers the core temperature in a hot environment as compared with the ingestion of a single bolus

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Cardiorespiratory Response to Low-Intensity Walking in Water and on Land in Elderly Women

) on a cycle ergometer and then rested, for 8 h sitting in an armchair. A control trial without any exercise was also performed. At 2 h after the end of exercise the subjects were given a meal. The plasma free and sulphated CA, oxygen uptake (

The prevalence of diabetes mellitus and impaired fasting glucose/glycaemia (IFG) in suburban and rural Nepal—the communities-based cross-sectional study during the democratic movements in 1990

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