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Dive into the research topics where Thanikavelu Manimaran is active.

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Featured researches published by Thanikavelu Manimaran.


Tetrahedron-asymmetry | 1993

Optical purification of profen drugs

Thanikavelu Manimaran; G. Patrick Stahly

Abstract Ibuprofen ( 1 ) and naproxen ( 2 ) are optically purified by crystallization of their sodium salts ( 3 and 4 ) from optically enriched mixtures. Treatment of an acetone solution of 76% ee 1 with NaOH afforded 100% ee 3 . Calculated melting point phase diagrams of compounds 1–4 are presented.


Organometallics | 1993

In situ generation of ruthenium-chiral phosphine complexes and their use in asymmetric hydrogenation

Thanikavelu Manimaran; Tse Chong Wu; W. Dirk Klobucar; Charles H. Kolich; G. Patrick Stahly; Frank R. Fronczek; Steven E. Watkins


Archive | 1992

Preparation of optically active aliphatic carboxylic acids

Thanikavelu Manimaran; Fred John Impastato


Archive | 1991

Asymmetric hydrogenation of aromatic-substituted olefins using organorhenium catalyst

W. Dirk Klobucar; Charles H. Kolich; Thanikavelu Manimaran


Archive | 1990

Resolution of racemic mixtures

Thanikavelu Manimaran; Fred John Impastato


Archive | 1992

RESOLUTION OF KETOPROFEN.

Thanikavelu Manimaran; Alicia Potter


Archive | 1991

Asymmetric hydrogenation of aromatic-substituted olefins using metal or metal alloy catalysts

Charles H. Kolich; Thanikavelu Manimaran; W. Dirk Klobucar


Archive | 1991

Asymmetric hydrogenation of aromatic-substituted olefins using cationic ruthenium(III) complexes

Thanikavelu Manimaran; W. Dirk Klobucar; Charles H. Kolich


Archive | 1992

Enantiomeric resolution of aryl-substituted aliphatic carboxylic acids

Thanikavelu Manimaran; G. Patrick Stahly; R. Carl Herndon


Archive | 1992

Asymmetric hydrogenation of aromatic-substituted olefins using organoruthenium catalyst

W. Dirk Klobucar; Charles H. Kolich; Thanikavelu Manimaran; Tse-Chong Wu

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