Thawatchai Santisuk
University of Illinois at Chicago
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Featured researches published by Thawatchai Santisuk.
Phytochemistry | 1993
Opinya A. Ekabo; Norman R. Farnsworth; Thawatchai Santisuk; Vichai Reutrakul
Abstract Salireposide, salirepin and two related novel phenolic glycosides named homaloside B [1-(2-methoxybenzoyloxy)methyl-5-hydroxyphenyl-β- d - glucopyranoside] and homaloside C (1-furoyloxymethyl-5-hydroxyphenyl-β- d -glucopyranoside) were isolated from the n-butanol-soluble fraction of Homalium ceylanicum. Two other new glucosides, 6- O -(3″,4″-dimethoxycinnamoyl)catapol and 3-hydroxy-β-inoyl-β- d -glucopyranoside were also isolated from this fraction. The structures were solved by chemical and NMR spectroscopic (COLOC, FLOCK, selective INEPT) methods.
Tetrahedron | 1997
Gloria L. Silva; Roberto R. Gil; Baoliang Cui; Heebyung Chai; Thawatchai Santisuk; Ekarath Srisook; Vichai Reutrakul; Patoomratana Tuchinda; Smaisukh Sophasan; Suparp Sujarit; Suchart Upatham; Sean M. Lynn; John E. Farthing; Shi-Lin Yang; Jane Lewis; Melanie J. O'neill; Norman R. Farnsworth; Geoffrey A. Cordell; John M. Pezzuto; A. Douglas Kinghorn
Abstract Coronalolide methyl ester (1), coronalolide (2), and coronalolic acid (3) were isolated from the leaves and/or stems of Gardenia coronaria. A further compound, methyl coronalolate acetate (4), was purified from the stems after methylation. The novel compounds 1–4 have the rare ring-A seco-cycloartane carbon skeleton and their structures were assigned on the basis of spectral data and molecular modeling, as well as X-ray crystallography performed on 1. Compounds 1 and 2 were also isolated from the leaves of Gardenia sootepensis and showed broad cytotoxic activity when evaluated against a panel of human cancer cell lines.
Phytochemistry | 1991
Patoomratana Tuchinda; Jinda Udchachon; Vichai Reutrakul; Thawatchai Santisuk; Walter C. Taylor; Norman R. Farnsworth; John M. Pezzuto; A. Douglas Kinghorn
Abstract From leaves and branches of Melodorum fruticosum , five butenolides have been isolated: (4 Z )-6-acetoxy-7-benzoyloxy-2,4-heptadien-4-olide, (4 E )-6-acetoxy-7-benzoyloxy-2,4-heptadien-4-olide, (4 Z )-7-benzoyloxy-6-hydroxy-2,4-heptadien-4-olide, (4 E )-7-benzoyloxy-6-hydroxy-2,4-heptadien-4-olide and (4 Z )-6-benzoyloxy-7-hydroxy-2,4-heptadien-4-olide. In addition, two known flavonoids (chrysin, pinocembrin) and benzoic acid were isolated. All butenolides showed cytotoxic activities in several tumour cell lines. The structures of the isolated compounds were elucidated by spectroscopic methods.
Phytochemistry | 1994
Patoomratana Tuchinda; Jinda Udchachon; Vichai Reutrakul; Thawatchai Santisuk; Brian W. Skelton; Allan H. White; Walter C. Taylor
Abstract Two novel pimarane diterpenes, 2α-acetoxysandaracopimaradien-1α-ol and sandaracopimaradien-1α,2α-diol, have been isolated from the hexane extract of the rhizomes of Kaempferia pulchra. Ethyl 4-methoxy-trans-cinnamate is also reported from the same source. The structures were assigned by spectroscopic methods. A single-crystal X-ray diffraction analysis confirmed the structure of 2α-acetoxysandaracopimaradien-1α-ol.
Journal of Natural Products | 1991
Norito Kaneda; John M. Pezzuto; D. Doel Soejarto; Ad Kinghorn; Norman R. Farnsworth; Thawatchai Santisuk; Patoomratana Tuchinda; Jinda Udchachon; Reutrakul
Planta Medica | 1993
P. Claeson; Ampai Panthong; Patoomratana Tuchinda; Vichai Reutrakul; D. Kanjanapothi; Walter C. Taylor; Thawatchai Santisuk
Journal of Natural Products | 1996
Sturm S; Roberto R. Gil; Heebyung Chai; Ngassapa Od; Thawatchai Santisuk; Reutrakul; Howe A; Moss M; Besterman Jm; Shi-Lin Yang; John E. Farthing; Tait Rm; Jane Lewis; Melanie J. O'neill; Norman R. Farnsworth; Geoffrey A. Cordell; John M. Pezzuto; Kinghorn Ad
Journal of Natural Products | 1993
Opinya A. Ekabo; Norman R. Farnsworth; Thawatchai Santisuk; Reutrakul
Planta Medica | 1990
Norito Kaneda; John M. Pezzuto; D. Doel Soejarto; A. D. Kinghorn; Norman R. Farnsworth; Patoomratana Tuchinda; J. Udchachon; Thawatchai Santisuk; Vichai Reutrakul
Planta Medica | 1992
Norito Kaneda; Heebyung Chai; John M. Pezzuto; Ad Kinghorn; Norman R. Farnsworth; Patoomratana Tuchinda; J. Udchachon; Thawatchai Santisuk; Vichai Reutrakul