Theodore J. Catino
Bayer
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Publication
Featured researches published by Theodore J. Catino.
Bioinformatics | 1999
Steven Bushnell; J. Budde; Theodore J. Catino; Jack Cole; A. Derti; R. Kelso; M. L. Collins; G. Molino; P. Sheridan; John E. Monahan; M. Urdea
MOTIVATION The sensitivity and specificity of branched DNA (bDNA) assays are derived in part through the judicious design of the capture and label extender probes. To minimize non-specific hybridization (NSH) events, which elevate assay background, candidate probes must be computer screened for complementarity with generic sequences present in the assay. RESULTS We present a software application which allows for rapid and flexible design of bDNA probesets for novel targets. It includes an algorithm for estimating the magnitude of NSH contribution to background, a mechanism for removing probes with elevated contributions, a methodology for the simultaneous design of probesets for multiple targets, and a graphical user interface which guides the user through the design steps. AVAILABILITY The program is available as a commercial package through the Pharmaceutical Drug Discovery program at Chiron Diagnostics.
Archive | 2004
Jon H. Astle; Lisa Allyn Boardman; Lawrence J. Burgart; Christopher C. Burgess; Theodore J. Catino; Poornima Dwivedi; Marcia E. Lewis; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam; Stephen N. Thibodeau
Archive | 2003
Jon H. Astle; Lisa Allyn Boardman; Sheryl Lynn Andrea Brown-Shimer; Lawrence J. Bugart; Christopher C. Burgess; Theodore J. Catino; Poornima Dwivedi; Maryanne Huntress; Karen Anne Johnson; Marcia E. Lewis; Peter J. Maimonis; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam; Stephen N. Thibodeau
Archive | 2001
Christopher C. Burgess; John H. Astle; Eddie Carroll; Theodore J. Catino; Poornima Dwivedi; Gary A. Molino; Arunthathi Thiagalingam; Marcia E. Lewis
Archive | 1999
Wilson O. Endege; Kathleen E. Steinmann; Jon H. Astle; Christopher C. Burgess; Steven E. Bushnell; Eddie Carroll; Theodore J. Catino; Adnan Derti; Donna Ford; Marcia E. Lewis; John E. Monahan; Robert Schlegel
Archive | 1999
Wilson O. Endege; Kathleen E. Steinmann; Jon H. Astle; Christopher C. Burgess; Eddie Carroll; Theodore J. Catino; Poornima Dwivedi; Donna Ford; Marcia E. Lewis; Gary A. Molino; John E. Monahan; Robert Schlegel
Archive | 2002
Jon H. Astle; Christopher C. Burgess; Theodore J. Catino; Poornima Dwivedi; Marcia E. Lewis; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam
Archive | 2001
Jon H. Astle; Christopher C. Burgess; Theodore J. Catino; Poornima Dwivedi; Marcia E. Lewis; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam; Stephen N. Thibodeau; Lawrence J. Burgart; Lisa Allyn Boardman
Archive | 2005
Christopher C. Burgess; Theodore J. Catino; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam; Stephen N. Thibodeau; Lisa Allyn Boardman; Lawrence J. Burgart; Marcia E. Lewis
Archive | 2003
Jon H. Astle; Lisa A. Boardman; Sheryl Brown-Shimer; Lawrence J. Bugart; Christopher C. Burgess; Theodore J. Catino; Poornima Dwivedi; Maryanne Huntress; Karen A. Johnson; Marcia E. Lewis; Peter Maimonis; Gary A. Molino; Susan H. Myerow; Arunthathi Thiagalingam; Stephen N. Thibodeau; シアガリンガム アランザッシ; アン ジョンソン カレン; シー． バージェス クリストファー; エイ． モリノ ゲイリイ; リン アンドレア ブラウン−シメール シェリル; ジェー． カティーノ シオドア; エイチ． アスツル ジョン; エイチ． マイアロウ スーザン; エヌ． シボドゥ スティーブン; ジェー． メイモニス ピーター; ドウィヴェディ プルニマ; イー． ルイス マーシャ; ハントレス メリーアン; アライン ボードマン リサ; ジェー． バガート ローレンス
