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international conference natural language processing | 2014

NLP-Oriented Contrastive Study of Linguistic Productions of Alzheimer’s and Control People

Maïté Boyé; Thi Mai Tran; Natalia Grabar

The increase in Alzheimers disease is due to the aging of the population and is the first cause of neurodegenerative disorders. Progressive development of cognitive, emotional and behavior troubles leads to the loss of autonomy and to dependency of people, which corresponds to the dementia phase. Language disorders are among the first clinical cognitive signs of the disease. Our objective is to study verbal communication of people affected by the Alzheimer’s disease at early to moderate stages. One particularity of our approach is that we work in ecological conversation situation: people are faced to persons they know. We study verbal productions of five people affected by the Alzheimer’s disease and of five control people. The conversations are transcribed and processed with the NLP methods and tools. Over thirty features grouped in four categories are studied. Our results indicate that the Alzheimer’s patients present lexical and semantic deficit and that, in several ways, their conversation is notably poorer than the conversation of the control people.


Quarterly Journal of Experimental Psychology | 2017

Co-occurrence frequency evaluated with large language corpora boosts semantic priming effects.

Angèle Brunellière; Laetitia Perre; Thi Mai Tran; Isabelle Bonnotte

In recent decades, many computational techniques have been developed to analyse the contextual usage of words in large language corpora. The present study examined whether the co-occurrence frequency obtained from large language corpora might boost purely semantic priming effects. Two experiments were conducted: one with conscious semantic priming, the other with subliminal semantic priming. Both experiments contrasted three semantic priming contexts: an unrelated priming context and two related priming contexts with word pairs that are semantically related and that co-occur either frequently or infrequently. In the conscious priming presentation (166-ms stimulus-onset asynchrony, SOA), a semantic priming effect was recorded in both related priming contexts, which was greater with higher co-occurrence frequency. In the subliminal priming presentation (66-ms SOA), no significant priming effect was shown, regardless of the related priming context. These results show that co-occurrence frequency boosts pure semantic priming effects and are discussed with reference to models of semantic network.


Clinical Linguistics & Phonetics | 2017

Inter-individual variability in discourse informativeness in elderly populations

Aurélie Pistono; Jérémie Pariente; C. Bezy; Josette Pastor; Thi Mai Tran; Antoine Renard; Marion Fossard; Jean-Luc Nespoulous; Mélanie Jucla

ABSTRACT An increasing number of studies focus on discourse production in patients with neurodegenerative diseases and underline its clinical usefulness. However, if this is to be used as a clinical tool, one needs to consider how normal discourse varies within cognitively unimpaired elderly populations. In the current study, the aim has been to investigate discourse macrolinguistic variability. For this, 123 participants aged between 55 and 84 were recruited. A cluster analysis of their discourse macrolinguistic features was conducted. Then, cluster characterisation based on socio-demographic and linguistic performance was tested (fluency, naming, syntax and spelling). This method aims to identify various profiles of speaker and informativeness and then see if inter-individual variability may be related to socio-demographic and/or linguistic aspects. Four clusters of informativeness were found but no socio-demographic features appeared significant. The fourth cluster, defined as ‘off topic’, had lower performance during linguistic tasks than others and thus the boundary between normality and pathology should be questioned.


American Journal of Alzheimers Disease and Other Dementias | 2017

Detection Test for Language Impairments in Adults and the Aged—A New Screening Test for Language Impairment Associated With Neurodegenerative Diseases: Validation and Normative Data:

Joël Macoir; Marion Fossard; Laurent Lefebvre; Laura Monetta; Antoine Renard; Thi Mai Tran; Maximiliano A. Wilson

To date, there is no quick screening test that could be used during routine office visits to accurately assess language disorders in neurodegenerative diseases. To fill this important gap, we developed the Detection Test for Language impairments in Adults and the Aged (DTLA), a quick, sensitive, standardized screening test designed to assess language disorders in adults and the elderly individuals. In Study 1, we describe the development of the DTLA. In Study 2, we report data on the DTLA’s validity and reliability. Finally, in Study 3, we establish normative data for the test. The DTLA has good convergent and discriminant validity as well as good internal consistency and test–retest reliability. Norms for the DTLA obtained from a sample of 545 healthy, community-dwelling, French-speaking adults from 4 French-speaking countries (Belgium, Canada (Quebec), France, and Switzerland) are provided. The development, validation, and standardization of the DTLA constitute a significant effort to meet the need for a language screening test adapted to neurodegenerative diseases.


Journal of Psycholinguistic Research | 2013

For a New Look at ‘Lexical Errors’: Evidence from Semantic Approximations with Verbs in Aphasia

Karine Duvignau; Thi Mai Tran; Mélanie Manchon

The ability to understand the similarity between two phenomena is fundamental for humans. Designated by the term analogy in psychology, this ability plays a role in the categorization of phenomena in the world and in the organisation of the linguistic system. The use of analogy in language often results in non-standard utterances, particularly in speakers with aphasia. These non-standard utterances are almost always studied in a nominal context and considered as errors. We propose a study of the verbal lexicon and present findings that measure, by an action-video naming task, the importance of verb-based non-standard utterances made by 17 speakers with aphasia (“la dame déshabille l’orange”/the lady undresses the orange, “elle casse la tomate”/she breaks the tomato). The first results we have obtained allow us to consider these type of utterances from a new perspective: we propose to eliminate the label of “error”, suggesting that they may be viewed as semantic approximations based upon a relationship of inter-domain synonymy and are ingrained in the heart of the lexical system.


SHS Web of Conferences | 2012

Les troubles du langage inauguraux et démence : étude des troubles lexicaux auprès de 28 patients au stade débutant de la maladie d'Alzheimer

Thi Mai Tran; Pauline Dasse; Léa Letellier; Claire Lubjinkowic; Juliette Thery; Marie-Anne Mackowiak


2ème Congrès Mondial de Linguistique Française | 2010

Expression du mouvement et pathologie du langage : Perspective typologique en aphasie

Efstathia Soroli; Maya Hickmann; Thi Mai Tran; Jean-Luc Nespoulous; Hélène Boudre


Congrès Mondial de Linguistique Française 2008 | 2008

Littéracie, SMS et troubles spécifiques du langage écrit

Thi Mai Tran; Marine Trancart; Domitille Servent; Faculté de Médecine; Lille Cedex


medical informatics europe | 2014

Contrastive conversational analysis of language production by Alzheimer's and control people.

Maïté Boyé; Natalia Grabar; Thi Mai Tran


Revue Neurologique | 2014

Effet du vieillissement normal sur la production lexicale de substantifs et de verbes

Antoine Renard; C. Bezy; S. Basaglias; Marion Fossard; Laurent Lefebvre; Thi Mai Tran; Jérémie Pariente

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C. Bezy

University of Toulouse

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