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Dive into the research topics where Thomas Buschmann is active.

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Featured researches published by Thomas Buschmann.


Digestive Diseases | 2003

Proteome Analysis for the Identification of Tumor-Associated Biomarkers in Gastrointestinal Cancer

Lüder M. Fels; Thomas Buschmann; Jörn Meuer; Marc A. Reymond; Stephanie Lamer; Christoph Röcken; Matthias P.A. Ebert

Gastrointestinal cancers are usually diagnosed at advanced stages, making a curative treatment difficult. Biomarkers can help to overcome this problem by allowing earlier diagnosis, and thus better therapy. Proteomics tools are novel technologies to identify such biomarkers. This review summarizes advances in biomarker detection using two-dimensional gel electrophoresis (2D-PAGE), chromatography and mass spectrometry technologies. 2D-PAGE combined with mass spectrometry has led to the identification of several differentially expressed proteins in cancer tissue. However, for serum analysis, 2D-PAGE has severe limitations. For serum-based cancer diagnosis, surface-enhanced laser desorption-ionization time-of-flight (SELDI-TOFTM) mass spectrometry is a promising new technology. The potential of proteins identified with this technology as novel cancer biomarkers still needs to be confirmed in clinical trials.


Pathology Research and Practice | 2004

Surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI TOF-MS) and ProteinChip technology in proteomics research.

Volker Seibert; Andreas Wiesner; Thomas Buschmann; Jörn Meuer


Briefings in Functional Genomics and Proteomics | 2005

Advances in clinical cancer proteomics: SELDI-ToF-mass spectrometry and biomarker discovery

Volker Seibert; Matthias Ebert; Thomas Buschmann


Archive | 2005

Membrane markers for use in cancer diagnosis and therapy

Silvia Tórtola-Pérez; Stephanie Lamer; Steffen Heim; Miriam Fuchs; Thomas Buschmann; Volker Seibert; Nikoleta-Kyriaki Fotiadis; Katrin Stedronsky; Jörn Meuer; Kirsten Rothmann-Cosic; Tatiana Ilynia; Lüder M. Fels


Archive | 2004

Differentially Expressed Tumour-specific Polypeptides for use in the Diagnosis and Treatment of Cancer

Jörn Meuer; Thomas Buschmann; Nikoleta-Kyriaki Fotiadis; Miriam Fuchs; Steffen Heim; Stephanie Lamer; Tatiana Lehnherr-Iliania; Silvia Tòrtola Pèrez; Kirsten Rothmann-Cosic; Volker Seibert; Katrin Stedronsky


Archive | 2002

Agents and methods for diagnosis and therapy of cancer and cancer risk assessment

Thomas Buschmann; Marie-Laure Fogeron; Steffen Heim; Tatiana Ilynia; Stephanie Lamer; Jörn Meuer; Kirsten Dr. Rothmann; Volker Seibert; Pérez Silvia Dr. Tortola; Der Linden Mark Dr. Van


Archive | 2003

Method for parallel preparation of rna and proteins from a tissue sample

Thomas Buschmann; Steffen Heim


Archive | 2003

Tumor marker proteins for diagnosis and therapy of cancer and cancer risk assessment

Volker Seibert; Stephanie Lamer; Kirsten Rothmann-Cosic; Silvia Tòrtola Pèrez; Tatiana Ilyina; Steffen Heim; Jörn Meuer; Thomas Buschmann; Marie-Laure Fogeron; Der Linden Mark Van


Archive | 2005

Advances in clinical cancer proteomics: SELDI-ToF-mass spectrometry and biomarker

Volker Seibert; Matthias Ebert; Thomas Buschmann


Archive | 2004

Polypeptides specifiques de tumeur d'expression differentielle utilisables pour le diagnostic et le traitement du cancer

Thomas Buschmann; Nikoleta-Kyriaki Fotiadis; Miriam Fuchs; Steffen Heim; Tatiana Ilynia; Stephanie Lamer; Jörn Meuer; Kirsten Rothmann-Cosic; Volker Seibert; Silvia Tòrtola Pèrez

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