Thomas E. Rogers | Researchain

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Transfusion Science | 1994

Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof

Phillipe R. Bovy; Joseph G. Rico; Thomas E. Rogers; Foe S. Tjoeng; Jeffery Alan Zablocki

Novel substituted β amino acid derivatives are provided which inhibit platelet aggregation and intermediates thereof. This invention also pertains to pharmaceutical compositions and methods of using such derivatives.

Synthetic Communications | 1995

Syntheses of Novel 3-Substituted-2′-deoxy-3-deazauridine Nucleosides

Balekudru Devadas; Thomas E. Rogers; Steven H. Gray

Abstract Syntheses of novel 3-ethynyl (8), 3-vinyl (10) and 3-acetoxy (13)-2′-deoxy-3-deazauridine analogs starting from the protected 2′-deoxy-3-deazauridine derivative 4 are described.

Archive | 1992

Substituted β-amino acid derivatives useful as platelet aggregation inhibitors

Philippe R. Bovy; Joseph G. Rico; Thomas E. Rogers; Foe S. Tjoeng; Jeffery Alan Zablocki

Archive | 1996

Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists

Peter G. Ruminski; Michael Clare; Paul W. Collins; Bipinchandra Nanubhai Desai; Richard John Lindmark; Joseph G. Rico; Thomas E. Rogers; Mark A. Russell

Archive | 1997

Para-substituted phenylpropanoic acid derivatives as integrin antagonists

Barbara B. Chen; Helen Y. Chen; Glen J. Gesicki; Richard A. Haack; James W. Malecha; Thomas D. Penning; Joseph G. Rico; Thomas E. Rogers; Peter G. Ruminski; Mark A. Russell; Stella S. Yu

Organic Process Research & Development | 2004

Pilot plant preparation of an αvβ3 integrin antagonist. Part 1. Process research and development of a (S)-β-amino acid ester intermediate: Synthesis via a scalable, diastereoselective imino-reformatsky reaction

Jerry D. Clark; Gerald A. Weisenburger; D. Keith Anderson; Pierre-Jean Colson; Albert D. Edney; Donald J. Gallagher; H. Peter Kleine; Carl M. Knable; Melissa K. Lantz; Christine M. V. Moore; James Murphy; Thomas E. Rogers; Peter G. Ruminski; Ajit S. Shah; Neil Storer; Bruce E. Wise

Archive | 1992

Substituted heterocyclic derivatives useful as platelet aggregation inhibitors

Philippe R. Bovy; Joseph G. Rico; Thomas E. Rogers; Foe S. Tjoeng; Jeffery Alan Zablocki

Archive | 1999

Heterocyclic glycyl beta-alanine derivatives as vitronectin antagonists

Nizal S. Chandrakumar; Bipinchandra Nanubhai Desai; Balekudru Devadas; Renee M. Huff; Ish K. Khanna; Shashidhar N. Rao; Joseph G. Rico; Thomas E. Rogers; Peter G. Ruminski; Mark A. Russell; Yi Yu; Alan F. Gasiecki; James W. Malecha; Julie M. Miyashiro

Archive | 1997

Para-substituted phenylene derivatives

Barbara B. Chen; Helen Y. Chen; Glen J. Gesicki; Richard A. Haack; James W. Malecha; Thomas D. Penning; Joseph G. Rico; Thomas E. Rogers; Peter G. Ruminski; Mark A. Russell; Stella S. Yu

Archive | 1996

Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid compounds and derivatives thereof

Peter G. Ruminski; Michael Clare; Paul W. Collins; Bipinchandra Nanubhai Desai; Richard John Lindmark; Joseph G. Rico; Thomas E. Rogers; Mark A. Russell

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