Thomas Horder

A Search for an Ideal Antigen for Therapeutic Immunization.

IT is inow more thaln twenty years since Wright introduced thio principle of therapeutic immunization against various microbic inifections by the injection of bacterial vaccines. Wrights discovery gave anl enormous impetus to the study of active immunity in miclobic diseases. Although at first the range of therapeutic tr ial of the method of specific inoculatioin was of necessity muclh wider than it is to-day, experience has demonstrated that the principle has a much greater value in SOi1iO iinfectionis thani in others, and in certain types of disease thalni in others. It is probable that weo do niot eveni yet know thio limits of the method, though it is already certain that it lhas limits, aild these of a very definiite kinid. Especially is its value limited when infections are gelneralized and wheni the tissue resistance of the patient is at a low level. In the treatmenit of such

Lumleian Lectures on Endocarditis

A mian of my temperament must needs be appalled by suclh knowledge, and though mind is thrilled by thought that the subject which I have choseni for these lectures is niot distinctly related to matters whicl the greatest of our Fellows illumined by the light of his genius, tremble at another thought-my incapacity to prove myself worthy of your choice. I shiall be satisfied if a few of my audience, generously disposed, mtay feel helped by reconsideration of old facts by a fi anik effort to discriminate between what -we do and whiat we do niot know, aild by the exercise of some care in suggesting o ow

The Mackenzie Davidson Lecture ON THE INFLUENCE OF RADIOLOGY UPON OUR CONCEPTIONS OF DISEASE

As a physician it has been my privilege to be very closely associated with the students and exponents of radiology ever since the science had its birth. I have therefore had full opportunities of watching its progress, from the small beginnings of the nineties to the great developments of tlle pr esent time. I am probably more indebted to my colleagues in this branch of our profession for help and guidance in diagnosis, and for treatment of mypatients, than to any other single br anch, not excluding the pathologists and the surgeons. I only say this to emphasize my interest in radiology. But this close association and its practical-results are not the subject of my lecture. Neither is it a consideration of all those individual diagnostic and therapeutic achievements of which the radiologist may well be proud, and upon which physicians become so dependent in the ordinary pursuit of their daily practice. I wish to deal with a larger aspect of -the subject, and to mark down some of the ways in which, as the result of these almost breathless strides that your science lhas taken, our ideas about certain diseases have