Thomas L. Fields

Bridgehead bicyclic iminium salts and enamines

Abstract The preparation of the novel bridgehead bicyclic iminium salts 3 and 4 and the transformation of 3 to the bridgehead bicyclic enamine 7 is described. Their structures are discussed in terms of Bredts Rule.

Functionalization of Penicillins via iodine atom transfer chemistry

Abstract Carbon  carbon bond formation via iodine atom transfer methodology represents a novel way to functionalize the 6-position of the penicillin nucleus. This work explores the synthetic scope and limitations to reactions of benzhydryl 6α-bromo-6β-iodopenicillanate 4a and its sulfone 4b with olefins.