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Featured researches published by Thomas N. Wheeler.


Synthetic Communications | 1988

A Convenient and Efficient Synthesis of 1-Aminocyclopropanecarboxylic Acid (ACC)

Thomas N. Wheeler; John A. Ray

Abstract A straightforward synthesis of 1-aminocyclopropanecarboxylic acid (ACC) has been developed. The key step in the synthesis is the thermal conversion of 1-t-butoxycarbonylcyclopropanecarboxylic acid to ACC.


Journal of Medicinal Chemistry | 1994

6-Azasteroids: structure-activity relationships for inhibition of type 1 and 2 human 5 alpha-reductase and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase.

Stephen V. Frye; Curt D. Haffner; Patrick Maloney; Robert A. Mook; George F. Dorsey; Roger N. Hiner; Cindy M. Cribbs; Thomas N. Wheeler; John A. Ray


Archive | 1993

Use of malonic acid derivative compounds for retarding plant growth

David Treadway Manning; James Joseph Cappy; Raymond Michael See; Anson Richard Cooke; Charles David Fritz; Thomas N. Wheeler


Journal of Organic Chemistry | 1987

Synthesis of 1-aminocyclopropenecarboxylic acid: the unsaturated analogue of ACC

Thomas N. Wheeler; John A. Ray


Archive | 1987

N-(5-substituted methylene) phenyl herbicides

Thomas N. Wheeler; Robert Benton Morland; Todd Alexander Craig


Archive | 1990

Pyridazinones having cardiotonic and beta blocking activity

Thomas N. Wheeler; Joel E. Shaffer; Terrence P. Kenakin


Archive | 1990

Dihydropyridine vasodilator agents

Thomas N. Wheeler; Terrence P. Kenakin


Archive | 1991

Substituted methoxyphenyl-4,5 dihydro-3(2H)-pridazinones having cardiotonic and beta blocking activities

Thomas N. Wheeler; Terrence P. Kenakin; Joel E. Shaffer


Archive | 1991

Pyridone nitriles useful in treating cardiovascular disease

Thomas N. Wheeler; Terrence P. Kenakin; Joel E. Shaffer


Archive | 1991

Dihydropyridine vasodilators agents

Thomas N. Wheeler; Terrence P. Kenakin

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John A. Ray

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