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Dive into the research topics where Timothy E. Barder is active.

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Featured researches published by Timothy E. Barder.


Journal of Organic Chemistry | 2008

Palladium-Catalyzed Carbonylation Reactions of Aryl Bromides at Atmospheric Pressure : A General System Based on Xantphos

Joseph R. Martinelli; Donald A. Watson; Dominique M. M. Freckmann; Timothy E. Barder; Stephen L. Buchwald

A method for the Pd-catalyzed carbonylation of aryl bromides has been developed using Xantphos as the ligand. This method is effective for the direct synthesis of Weinreb amides, primary and secondary benzamides, and methyl esters from the corresponding aryl bromides at atmospheric pressure. In addition, a putative catalytic intermediate, (Xanphos)Pd(Br)benzoyl, was prepared and an X-ray crystal structure was obtained revealing an unusual cis-coordination mode of Xantphos in this palladium-acyl complex.


Journal of the American Chemical Society | 2005

Catalysts for suzuki-miyaura coupling processes : Scope and studies of the effect of ligand structure

Timothy E. Barder; Shawn D. Walker; and Joseph R. Martinelli; Stephen L. Buchwald


Angewandte Chemie | 2004

A Rationally Designed Universal Catalyst for Suzuki–Miyaura Coupling Processes

Shawn D. Walker; Timothy E. Barder; Joseph R. Martinelli; Stephen L. Buchwald


Journal of Organic Chemistry | 2004

Copper−Diamine-Catalyzed N-Arylation of Pyrroles, Pyrazoles, Indazoles, Imidazoles, and Triazoles

Jon C. Antilla; Jeremy M. Baskin; Timothy E. Barder; Stephen L. Buchwald


Angewandte Chemie | 2007

Palladium‐Catalyzed Borylation of Aryl Chlorides: Scope, Applications, and Computational Studies

Kelvin L. Billingsley; Timothy E. Barder; Stephen L. Buchwald


Angewandte Chemie | 2006

Significantly Improved Method for the Pd‐Catalyzed Coupling of Phenols with Aryl Halides: Understanding Ligand Effects

Carlos H. Burgos; Timothy E. Barder; Xiaohua Huang; Stephen L. Buchwald


Journal of the American Chemical Society | 2007

Pd-Catalyzed Amidations of Aryl Chlorides Using Monodentate Biaryl Phosphine Ligands: A Kinetic, Computational, and Synthetic Investigation

Takashi Ikawa; Timothy E. Barder; Mark R. Biscoe; Stephen L. Buchwald


Journal of the American Chemical Society | 2007

Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen.

Timothy E. Barder; Stephen L. Buchwald


Organometallics | 2007

Structural Insights into Active Catalyst Structures and Oxidative Addition to (Biaryl)phosphine−Palladium Complexes via Density Functional Theory and Experimental Studies

Timothy E. Barder; and Mark R. Biscoe; Stephen L. Buchwald


Journal of the American Chemical Society | 2006

Synthesis, structural, and electron topographical analyses of a dialkylbiaryl phosphine/arene-ligated palladium(I) dimer: enhanced reactivity in Suzuki-Miyaura coupling reactions.

Timothy E. Barder

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Stephen L. Buchwald

Massachusetts Institute of Technology

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Mark R. Biscoe

Massachusetts Institute of Technology

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Shawn D. Walker

Massachusetts Institute of Technology

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Carlos H. Burgos

Massachusetts Institute of Technology

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Dominique M. M. Freckmann

Massachusetts Institute of Technology

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Eric McNeill

Massachusetts Institute of Technology

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Jon C. Antilla

University of South Florida

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