Tina Dietrich-Ntoukas

Combined retinal artery and vein occlusions associated with interferon beta therapy

Interferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.ZusammenfassungInterferon (IFN)-β wird zur Behandlung einer multiplen Sklerose eingesetzt. Unter dieser Therapie können thromboembolische Komplikationen auftreten. Wir berichten von einer Patientin, bei der sich nach 10-jähriger IFN-β-Behandlung eine venöse Staseretinopathie in Kombination mit Arterienastverschlüssen entwickelte. Thromboembolische und kardiovaskuläre Risikofaktoren, die für das Ereignis verantwortlich sein könnten, wurden ausgeschlossen. Das Auftreten eines kombinierten Gefäßverschlusses lässt somit einen Zusammenhang zur langjährigen Therapie mit IFN-β vermuten.AbstractInterferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.

Kombinierter retinaler arteriovenöser Verschluss unter Interferon-β-Therapie

Interferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.ZusammenfassungInterferon (IFN)-β wird zur Behandlung einer multiplen Sklerose eingesetzt. Unter dieser Therapie können thromboembolische Komplikationen auftreten. Wir berichten von einer Patientin, bei der sich nach 10-jähriger IFN-β-Behandlung eine venöse Staseretinopathie in Kombination mit Arterienastverschlüssen entwickelte. Thromboembolische und kardiovaskuläre Risikofaktoren, die für das Ereignis verantwortlich sein könnten, wurden ausgeschlossen. Das Auftreten eines kombinierten Gefäßverschlusses lässt somit einen Zusammenhang zur langjährigen Therapie mit IFN-β vermuten.AbstractInterferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.

Okuläre Hypotonie – Ursachen und therapeutische Möglichkeiten aus Sicht des Netzhautchirurgen

Ocular hypotension is a result of a lack of production or a loss of intraocular fluid. Intraocular inflammation, drugs, or proliferative vitreoretinopathy (PVR) with overgrowth of the ciliary body can result in reduced secretion of intraocular fluid. Loss of intraocular fluid can result from external loss, such as in fistulating surgery or trauma, or internally, e.g. from cyclodialysis clefts or retinal detachment. In this review, we discuss the causal therapy of ocular hypotension: fixation of the ciliary body, removal of ciliary body membranes, surgery for PVR, choice of tamponade, possibilities and limitations of an iris diaphragm, and pharmacological options.

Kombinierter retinaler arteriovenöser Verschluss unter Interferon-β-Therapie@@@Combined retinal artery and vein occlusions associated with interferon beta therapy

Interferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.ZusammenfassungInterferon (IFN)-β wird zur Behandlung einer multiplen Sklerose eingesetzt. Unter dieser Therapie können thromboembolische Komplikationen auftreten. Wir berichten von einer Patientin, bei der sich nach 10-jähriger IFN-β-Behandlung eine venöse Staseretinopathie in Kombination mit Arterienastverschlüssen entwickelte. Thromboembolische und kardiovaskuläre Risikofaktoren, die für das Ereignis verantwortlich sein könnten, wurden ausgeschlossen. Das Auftreten eines kombinierten Gefäßverschlusses lässt somit einen Zusammenhang zur langjährigen Therapie mit IFN-β vermuten.AbstractInterferon (IFN) beta is commonly used in the treatment of multiple sclerosis. Thromboembolic complications may be associated with this therapy. We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta.